1
A Pharmacokinetic Study to Assess the Effect of Food in Healthy Male Participants Receiving TMC435
Condition(s):HealthyLast Updated:April 29, 2013Completed
TMC435: 117 Clinical Trials, Page 1 of 12
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2
A Study to Evaluate the Efficacy, Safety and Tolerability of TMC435 in Combination With PegIFN Alfa-2a (Pegasys) and Ribavirin (Copegus) in Treatment-Naïve or Treatment-Experienced, Chronic Hepatitis C Virus Genotype-4 Infected Patients
Condition(s):Hepatitis CLast Updated:July 7, 2017Completed
3
A Study to Assess the Absolute Bioavailability and Pharmacokinetics of Simeprevir (TMC435) Administered as Single Oral Doses of TMC435 and an Intravenous Microdose of [3H]-TMC435 in Healthy Male Patients
Condition(s):Healthy Male ParticipantsLast Updated:March 28, 2014Completed
4
A Study to Examine the Pharmacokinetics, Safety and Tolerability of Multiple Oral Doses of TMC435 in Healthy Chinese Participants
Condition(s):HealthyLast Updated:September 30, 2014Completed
5
A Study in Healthy Participants Investigating the Effect of TMC435 on the Pharmacokinetics of Immunosuppressants Cyclosporine and Tacrolimus
Condition(s):Hepatitis C VirusLast Updated:November 1, 2012Completed
6
TMC435-TiDP16-C113: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of TMC435
Condition(s):Hepatitis C VirusLast Updated:October 14, 2013Completed
7
TMC435-TiDP16-C126 – Trial to Investigate the Effect of Severe Renal Impairment on the Pharmacokinetics and Safety of TMC435
Condition(s):Hepatitis C VirusLast Updated:October 14, 2013Completed
8
A Pharmacokinetic Interaction Study Between TMC435, Atorvastatin and Simvastatin in Healthy Participants
Condition(s):Healthy ParticipantsLast Updated:March 4, 2013Completed
9
A Study of TMC435 in Combination With Peginterferon Alfa-2A and Ribavirin for Hepatitis C Virus Genotype-1 Infected Patients Who Participated in a Control Group of a TMC435 Study
Condition(s):Hepatitis CLast Updated:April 4, 2016Completed
10
A Study to Assess Bioavailability & Food Effect of Different Liquid and Capsule Formulations of TMC435.
Condition(s):Healthy VolunteersLast Updated:June 25, 2013Completed