1
Quality of Life Measures in Patients With Retinal Degeneration
Condition(s):Retinal DegenerationLast Updated:November 8, 2018Completed
Retinal Degeneration: 1828 Clinical Trials, Page 1 of 19
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2
Natural History Study of CEP290-Related Retinal Degeneration
Condition(s):Blindness; Leber Congenital Amaurosis 10; Vision Disorders; Eye Diseases; Eye Diseases, Hereditary; Eye Disorders Congenital; Retinal Disease; Retinal DegenerationLast Updated:August 28, 2019Recruiting
3
Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration
Condition(s):Retinal DegenerationsLast Updated:December 12, 2014Unknown status
4
Molecular Genetics of Retinal Degenerations
Condition(s):Retinal Degeneration; Retinitis PigmentosaLast Updated:April 4, 2018Completed
5
Retinal Imaging in Patients With Inherited Retinal Degenerations
Condition(s):Retinitis PigmentosaLast Updated:November 9, 2019Recruiting
6
Rate of Progression in USH2A Related Retinal Degeneration
Condition(s):Usher Syndrome, Type 2A; Retinitis Pigmentosa 39Last Updated:October 10, 2019Active, not recruiting
7
Stem Cell Therapy for Outer Retinal Degenerations
Condition(s):Age Related Macular Degeneration; Stargardt’s Disease; Exudative Age-related Macular DegenerationLast Updated:August 8, 2017Unknown status
8
Color Vision as a Measure for Inherited Retinal Diseases
Condition(s):Healthy Volunteer; Retinal Disease; Inherited Retinal DegenerationLast Updated:October 5, 2017Completed
9
Safety Study of RPE65 Gene Therapy to Treat Leber Congenital Amaurosis
Condition(s):Retinal DegenerationLast Updated:December 4, 2015Completed
10
Rate of Progression in EYS Related Retinal Degeneration
Condition(s):Retinitis Pigmentosa; Eye DiseasesLast Updated:October 17, 2019Not yet recruiting
11
Pain Perception at Laser Treatment
Condition(s):Laser Therapy, Low-LevelLast Updated:May 19, 2010Completed
12
Saffron Supplementation in Stargardt’s Disease
Condition(s):Retinal Degeneration; Genetic Disease; Single-Gene Defects; Macular DystrophyLast Updated:July 18, 2017Unknown status
13
Natural History of Eye Diseases Related to ABCA4 Mutations
Condition(s):Retinal Degeneration; ABCA4-Related RetinopathiesLast Updated:October 23, 2019Recruiting
14
Safety and Efficacy of Subretinal Implants for Partial Restoration of Vision in Blind Patients
Condition(s):Retinitis Pigmentosa; Retinal DegenerationLast Updated:September 3, 2018Completed
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Safety & Efficacy of Subretinal Implants for Partial Restoration of Vision in Blind Patients
Condition(s):Retinal Degeneration; Retinitis PigmentosaLast Updated:March 28, 2017Completed
16
Argus® II Retinal Prosthesis System Post-Market Surveillance Study
Condition(s):Outer Retinal Degeneration; Retinitis PigmentosaLast Updated:June 21, 2019Active, not recruiting
17
Cell Collection to Study Eye Diseases
Condition(s):Retinal Disease; AMD; Retinal DegenerationLast Updated:November 7, 2019Recruiting
18
The Association of the Peripheral Retinal Changes and Genotypic Changes in Patients With Age Related Macular Degeneration
Condition(s):Peripheral Retinal Degenerations, Age Related Macular Degeneration PolymorphismsLast Updated:April 2, 2018Completed
19
High Resolution Retinal Imaging
Condition(s):Stargardts; Retinitis Pigmentosa; Age-related Macular Degeneration; Choroideremia; Geographic AtrophyLast Updated:August 8, 2019Recruiting
20
Impact on Daily Life of Patients Using the Subretinal Implant RETINA IMPLANT Alpha AMS
Condition(s):Retinal Degeneration; Inherited Retinal Dystrophy Primarily Involving Sensory RetinaLast Updated:April 17, 2019Terminated
21
Assessment of Visual Function With a Portable Brain-computer Interface
Condition(s):Glaucoma; Age Related Macular Degeneration; Optic Neuropathy; Retinal DegenerationLast Updated:February 11, 2019Enrolling by invitation
22
Ophthalmologic Safety of Long Term Treatment With Pramipexole Compared to Bromocriptine or Other Dopamine Agonists in Patients With Parkinson’s Disease
Condition(s):Parkinson DiseaseLast Updated:September 4, 2014Completed
23
A Multi-Center Study of Reading Rehabilitation in Macular Disease
Condition(s):Age Related Maculopathy; Retinal DegenerationLast Updated:February 24, 2015Completed
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Measuring Reading Rehabilitation Outcomes
Condition(s):Age Related Maculopathy; Retinal DegenerationLast Updated:February 3, 2009Completed
25
Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)
Condition(s):Inherited Ophthalmic Diseases; Inherited Retinal DegenerationLast Updated:August 5, 2019Terminated
26
Single Ascending Dose Study in Participants With LCA10
Condition(s):Blindness; Leber Congenital Amaurosis 10; Vision Disorders; Eye Diseases; Eye Diseases, Hereditary; Eye Disorders Congenital; Retinal Disease; Retinal DegenerationLast Updated:October 25, 2019Recruiting
27
Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous Neurodegeneration
Condition(s):Retinal Degeneration; Primary Open-Angle GlaucomaLast Updated:July 19, 2017Unknown status
28
Clinical and Pathophysiological Description of Ocular Ischemic Syndrome
Condition(s):Retinal Degeneration; Diabetic RetinopathyLast Updated:September 7, 2012Completed
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Intravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma.
Condition(s):Retinal Degeneration; Primary Open-angle GlaucomaLast Updated:April 16, 2019Completed
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Evaluation of Visual and Task Performance
Condition(s):Glaucoma; Macular Degeneration; Glaucoma Suspect; Optic Neuropathy; Retinal Degeneration; Visual Pathway DisorderLast Updated:October 25, 2019Enrolling by invitation
31
Clinical Trial of Lutein for Patients With Retinitis Pigmentosa Receiving Vitamin A
Condition(s):Retinitis PigmentosaLast Updated:December 12, 2013Completed
32
Rod and Cone Mediated Function in Retinal Disease
Condition(s):Retinal Degeneration; Retinitis Pigmentosa; Stargardt’s DiseaseLast Updated:November 14, 2019Recruiting
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The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients
Condition(s):Retinitis Pigmentosa; Retinal Degeneration; CannabisLast Updated:July 31, 2018Recruiting
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Gene Therapy for Blindness Caused by Choroideremia
Condition(s):ChoroideremiaLast Updated:November 16, 2017Completed
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Performance of Long-wavelength Autofluorescence Imaging
Condition(s):Retinal Disease; Retinal Degeneration; Retinal DystrophiesLast Updated:August 20, 2018Not yet recruiting
36
Evaluation of Discomfort Associated With Scleral Depression During Retina Examinations
Condition(s):Retina–Diseases; Retinal Detachment; Retinal DegenerationLast Updated:October 2, 2019Completed
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Phase I/II Follow-up Study of SAR422459 in Patients With Stargardt’s Macular Degeneration
Condition(s):Stargardt’s DiseaseLast Updated:October 2, 2019Active, not recruiting
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Phase I/II Study of SAR422459 in Patients With Stargardt’s Macular Degeneration
Condition(s):Stargardt’s DiseaseLast Updated:September 26, 2019Terminated
39
Stem Cells Therapy in Degenerative Diseases of the Retina
Condition(s):Retinal Degeneration; Retinitis Pigmentosa; Age Related Macular Degeneration; Stargardt Disease 1Last Updated:December 14, 2018Enrolling by invitation
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Clinical Gene Therapy Protocol for the Treatment of Retinal Dystrophy Caused by Defects in RPE65
Condition(s):Leber Congenital AmaurosisLast Updated:October 6, 2015Completed
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Safety and Efficacy of the Alpha AMS Subretinal Implant
Condition(s):Retinitis PigmentosaLast Updated:November 16, 2017Completed
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A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa
Condition(s):Retinitis PigmentosaLast Updated:November 15, 2016Completed
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The Effect of Laser Treatment on Macular Pigment of Eye in Cases With Diabetes
Condition(s):Diabetic Retinopathy; Retinal Degeneration; Macula Abnormality; Laser Burn of RetinaLast Updated:May 10, 2017Completed
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A Study of Encapsulated Cell Technology (ECT) Implant for Patients With Late Stage Retinitis Pigmentosa
Condition(s):Retinitis PigmentosaLast Updated:November 15, 2016Completed
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Repository for Inherited Eye Diseases
Condition(s):Retinitis Pigmentosa; Inherited Ophthalmic DiseasesLast Updated:November 14, 2019Enrolling by invitation
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Dual Wavelength OCT
Condition(s):AMD; Diabetic Retinopathy; Retinal Degeneration; Retinal DystrophiesLast Updated:February 15, 2019Recruiting
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Observational Study of the Argus® II Retinal Prosthesis System
Condition(s):Retinitis PigmentosaLast Updated:April 23, 2015Unknown status
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Safety and Effectiveness Investigation for Dry, Non-Exudative Age Related Macular Degeneration (AMD) Using Rheopheresis
Condition(s):Age-Related MaculopathyLast Updated:November 6, 2007Suspended
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The Effect of Eggs and Egg Products on Macular Pigment
Condition(s):Age-related Macular DegenerationLast Updated:April 25, 2018Completed
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Randomized Trial for Retinitis Pigmentosa
Condition(s):Retinitis PigmentosaLast Updated:September 16, 2009Completed
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Electro-acupuncture and Transcorneal Electrical Stimulation (TES) for Retinitis Pigmentosa
Condition(s):Retinitis PigmentosaLast Updated:July 27, 2018Active, not recruiting
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Long-Term Efficacy in AMD of Rheopheresis in North America
Condition(s):Macular DegenerationLast Updated:September 21, 2006Unknown status
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Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases
Condition(s):Retinitis PigmentosaLast Updated:December 3, 2014Unknown status
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Oral Hydroxychloroquine (HCQ) for Retinitis Pigmentosa Caused by P23H- Rhodopsin (RHO)
Condition(s):Retinitis PigmentosaLast Updated:October 24, 2019Not yet recruiting
55
Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers
Condition(s):Healthy; Muscular Dystrophy; Retinal Degeneration; Skin Diseases; Virus DiseasesLast Updated:March 4, 2008Completed
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The Effect of Oral Administration of 9-cis β Carotene Rich Powder of the Alga Dunaliella Bardawil
Condition(s):Retinitis PigmentosaLast Updated:February 17, 2019Recruiting
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The Effect of Oral Administration of 9-cis Rich Powder of the Alga Dunaliella Bardawil on Visual Functions im Patients With Retinitis Pigmentosa
Condition(s):Retinitis PigmentosaLast Updated:December 19, 2013Completed
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Study of SAR421869 in Patients With Retinitis Pigmentosa Associated With Usher Syndrome Type 1B
Condition(s):Usher Syndrome; Retinitis PigmentosaLast Updated:September 26, 2019Terminated
59
Clinical Implication of Retinitis Pigmentosa Molecular Diagnostic Using High Throughput Sequencing.
Condition(s):Retinitis PigmentosaLast Updated:August 11, 2016Unknown status
60
Rasagiline (Azilect) – Neuroprotection for Macula-off Retinal Detachment
Condition(s):Retinal DetachmentLast Updated:February 18, 2019Terminated
61
Genetics and Markers of Degenerative and Inflammatory Eye Diseases
Condition(s):Diabetic Retinopathy; Age-Related Macular Degeneration (AMD); UveitisLast Updated:December 7, 2018Completed
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Trial of Ocular Subretinal Injection of a Recombinant Adeno-Associated Virus (rAAV2-VMD2-hMERTK) Gene Vector to Patients With Retinal Disease Due to MERTK Mutations
Condition(s):Retinal DiseaseLast Updated:November 29, 2011Recruiting
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BioCurrent Electrical Stimulation for the Treatment of Dry ARMD
Condition(s):Dry Macular DegenerationLast Updated:June 2, 2018Withdrawn
64
Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular Degeneration
Condition(s):Age-Related Maculopathy; Age-Related Maculopathies; Eye Diseases; Retinal Degeneration; Macular DegenerationLast Updated:March 20, 2015Completed
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The Relationship Between Structure and Visual Function in Myopia Foveoschisis
Condition(s):High MyopiaLast Updated:September 17, 2019Suspended
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Macular Buckle With Three-armed Silicone
Condition(s):High Myopia; Posterior StaphylomaLast Updated:June 18, 2014Completed
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Clinical and Molecular Investigations Into Ciliopathies
Condition(s):CiliopathyLast Updated:October 18, 2019Completed
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Phase I Trial of Gene Vector to Patients With Retinal Disease Due to RPE65 Mutations
Condition(s):Amaurosis of Leber; Retinal DiseasesLast Updated:October 31, 2019Active, not recruiting
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Atropine 0.01% Eye Drops in Myopia Study
Condition(s):Myopia, ProgressiveLast Updated:April 4, 2019Recruiting
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A Study to Determine the Long-Term Safety, Tolerability and Biological Activity of UshStat® in Patients With Usher Syndrome Type 1B
Condition(s):Usher SyndromeLast Updated:October 2, 2019Active, not recruiting
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Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases
Condition(s):Eye DiseasesLast Updated:June 30, 2017Completed
72
Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration
Condition(s):Macular Degeneration; Age-related Maculopathies; Age-related Maculopathy; Maculopathies,Age-related; Maculopathy,Age-related; Retinal Degeneration; Retinal Neovascularization; Eye DiseasesLast Updated:August 30, 2017Completed
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Aflibercept After Ranibizumab in Exudative Age-related Macular Degeneration
Condition(s):Macular Degeneration; Wet Macular Degeneration; Retinal Degeneration; Retinal Diseases; Eye DiseasesLast Updated:June 20, 2016Completed
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“Natural History” Study of Choroideremia
Condition(s):ChoroideremiaLast Updated:April 23, 2019Active, not recruiting
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Argus II Retinal Prosthesis System – Better Vision RP Study
Condition(s):Retinitis PigmentosaLast Updated:June 21, 2019Withdrawn
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Post-Market Study of the Argus® II Retinal Prosthesis System – France
Condition(s):Retinitis PigmentosaLast Updated:March 29, 2019Completed
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THOR – Tübingen Choroideremia Gene Therapy Trial
Condition(s):ChoroideremiaLast Updated:September 25, 2018Active, not recruiting
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Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic Atrophy
Condition(s):Age-Related Maculopathy; Age-Related Maculopathies; Eye Diseases; Retinal Degeneration; Macular DegenerationLast Updated:March 27, 2013Completed
79
Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of OPT-302 With or Without Lucentis™ in Patients With Wet AMD
Condition(s):Eye Diseases; Macular Degeneration; Retinal Diseases; Retinal Degeneration; Neovascularization, PathologicLast Updated:November 2, 2017Completed
80
A Natural History of the Progression of Stargardt Disease: Retrospective and Prospective Studies
Condition(s):Stargardt DiseaseLast Updated:October 30, 2019Completed
81
Clinical Evaluation of Patients With X-linked Retinitis Pigmentosa (XLRP)
Condition(s):X-Linked Retinitis PigmentosaLast Updated:March 18, 2019Recruiting
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To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)
Condition(s):Dry Age-related Macular Degeneration; Macular Degeneration; Retinal Disease; Retinal Degeneration; Geographic Atrophy; Macular AtrophyLast Updated:October 23, 2019Recruiting
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Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa
Condition(s):Retinitis Pigmentosa; Retinal Diseases; Eye Diseases; Eye Disease, Hereditary; Retinal DegenerationLast Updated:April 12, 2016Completed
84
Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)
Condition(s):Age-related Macular Degeneration; Macular Degeneration; Wet Macular Degeneration; Retinal Degeneration; Retinal Diseases; Eye DiseasesLast Updated:July 8, 2019Not yet recruiting
85
Visual Rehabilitation Through Acoustic Biofeedback With Retimax Vision Trainer in Patients With Advanced Age-related Macular Degeneration
Condition(s):Macular Degeneration Advanced; Macular Degeneration, Senile; Macular Degeneration, Dry; Macular Scar; Macular Degeneration NonexudativeLast Updated:September 9, 2019Completed
86
Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMD
Condition(s):Age-Related Macular Degeneration; Macular Degeneration; Wet Macular Degeneration; Retinal Degeneration; Retinal Diseases; Eye DiseasesLast Updated:September 24, 2019Completed
87
Changes of Macular Pigment and Parameters of Eyes After YAG Laser Treatment in Cases With Capsule Opacification
Condition(s):Posterior Capsule Opacification; Retinal Degeneration; Retinal Detachment; Anterior Chamber Angle Congestion; Macula Edema; Macular Pigmentation; Choroid DiseaseLast Updated:July 28, 2019Completed
88
X-82 to Treat Age-related Macular Degeneration
Condition(s):Age-Related Macular Degeneration (AMD); Macular Degeneration; Exudative Age-related Macular Degeneration; AMD; Macular Degeneration, Age-related, 10; Eye Diseases; Retinal Degeneration; Retinal DiseasesLast Updated:June 27, 2018Terminated
89
Triple Therapy – PDT Plus IVD and Intravitreal Ranibizumab Versus Lucentis Monotherapy to Treat Age-Related Macular Degeneration
Condition(s):Age Related Macular DegenerationLast Updated:May 25, 2010Completed
90
Safety and Tolerability Study of AAV2-sFLT01 in Patients With Neovascular Age-Related Macular Degeneration (AMD)
Condition(s):Macular Degeneration; Age-Related Maculopathies; Age-Related Maculopathy; Maculopathies, Age-Related; Maculopathy, Age-Related; Retinal Degeneration; Retinal Neovascularization; Gene Therapy; Therapy, Gene; Eye DiseasesLast Updated:August 21, 2018Completed
91
A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration.
Condition(s):Wet Macular DegenerationLast Updated:October 1, 2019Recruiting
92
EAGLE: Evaluating Genotypes Using Intravitreal Aflibercept Injection
Condition(s):Macular Degeneration; Wet Macular DegenerationLast Updated:February 23, 2016Unknown status
93
A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial)
Condition(s):Age Related Macular Degeneration; Choroidal Neovascular Membrane; Subfoveal Neovascular Age-Related Macular Degeneration; Macular Degeneration; Wet Age-Related Macular DegenerationLast Updated:November 3, 2016Terminated
94
ADVM-022 Intravitreal Gene Therapy for Wet AMD
Condition(s):Wet Age-related Macular Degeneration; Neovascular Age-related Macular DegenerationLast Updated:October 11, 2019Recruiting
95
Treatment of Dry Age Related Macular Degeneration Disease With Retinal Pigment Epithelium Derived From Human Embryonic Stem Cells
Condition(s):Dry Age-related Macular DegenerationLast Updated:January 30, 2018Recruiting
96
Subretinal Transplantation of Retinal Pigment Epitheliums in Treatment of Age-related Macular Degeneration Diseases
Condition(s):Dry Age-related Macular DegenerationLast Updated:January 31, 2018Recruiting
97
Safety Study for Treatment of Wet Macular Degeneration Using the TheraSight(TM) Ocular Brachytherapy System
Condition(s):Macular Degeneration; Choroidal NeovascularizationLast Updated:June 23, 2005Unknown status
98
RETINA IMPLANT Alpha AMS in Blind Patients With Retinitis Pigmentosa
Condition(s):Retinitis PigmentosaLast Updated:May 8, 2019Withdrawn
99
Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS)
Condition(s):X-linked RetinoschisisLast Updated:July 10, 2019Active, not recruiting
100
Evaluation of Retinal and Vascular Features in Macular Degeneration After Intravitreal Injections of Bevacizumab
Condition(s):Exudative Age-related Macular DegenerationLast Updated:October 22, 2019Completed