1
The Effect of Oxytocin on Placebo Analgesia: an Experimental Study in Healthy Volunteers
Condition(s):Mechanisms and Modulators of Placebo Analgesia in Healthy VolunteersLast Updated:June 25, 2013Completed
Placebos: 59955 Clinical Trials, Page 1 of 600
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2
A Crossover Study on the Blinding Effect of a New Pragmatic Placebo Needle
Condition(s):Device IneffectiveLast Updated:December 23, 2017Completed
3
Efficacy of Open Label Placebo in Children With FGIDs
Condition(s):Functional Abdominal Pain; Functional Dyspepsia; Irritable Bowel Syndrome; Functional Gastrointestinal DisordersLast Updated:October 23, 2018Recruiting
4
Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size
Condition(s):Placebo Effect; Placebo Drug InteractionLast Updated:March 1, 2017Completed
5
Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease
Condition(s):Dry Eye DiseaseLast Updated:August 3, 2018Terminated
6
Experimental Pain Reporting Accuracy and Placebo Response
Condition(s):Healthy; Placebo Effect; PainLast Updated:May 13, 2019Recruiting
7
Brain Imaging and Pain: Analysis of Placebo Analgesia
Condition(s):Brain Imaging of Placebo AnalgesiaLast Updated:March 19, 2015Completed
8
Statin Therapy Versus Placebo Prior to Prostatectomy
Condition(s):Cancer; Prostate CancerLast Updated:June 13, 2017Completed
9
Metformin for the Prevention of Episodic Migraine (MPEM)
Condition(s):MigraineLast Updated:February 4, 2019Active, not recruiting
10
Zonegran for the Treatment of Weight Gain Associated With Psychotropic Medication Use: A Placebo-Controlled Trial
Condition(s):ObesityLast Updated:August 30, 2012Completed
11
Efficacy and Safety of Ofatumumab Compared to Placebo in Patients With Relapsing Multiple Sclerosis Followed by Extended Treatment With Open-label Ofatumumab
Condition(s):Relapsing Multiple SclerosisLast Updated:October 14, 2019Active, not recruiting
12
Randomized Trial Comparing Sitagliptin to Placebo in Closed Loop
Condition(s):Diabetes Mellitus, Type 1Last Updated:July 30, 2018Completed
13
Effect of Brodalumab Compared to Placebo on Vascular Inflammation in Moderate-to-severe Psoriasis
Condition(s):PsoriasisLast Updated:July 9, 2019Recruiting
14
Does the Understanding of Placebo Mechanisms Compensate for the Loss of Efficacy Associated With Open Label Placebo
Condition(s):Acute PainLast Updated:May 14, 2019Recruiting
15
Dose Finding Study to Assess Octenidine Mouthwash Concentrations in Comparison to Placebo
Condition(s):GingivitisLast Updated:May 12, 2014Completed
16
A Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic Features
Condition(s):Psychotic Depression; Severe Major Depression With Psychotic Features; PsychosisLast Updated:May 4, 2017Terminated
17
Measuring Placebo Effect by Elimination and Investigating Mechanism of Action
Condition(s):Placebo Effect; Placebo Mechanisms of ActionLast Updated:December 11, 2011Completed
18
Characterization of Placebo Responses in Stable Asthma
Condition(s):Asthma Placebo EffectsLast Updated:March 29, 2017Completed
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The Placebo Effect May Involve Modulating Drug Bioavailability
Condition(s):Placebo Effect; Drug Half Life; PharmacokineticsLast Updated:April 8, 2013Completed
20
Amitiza® Plus GoLYTELY® Versus Placebo Plus GoLYTELY® for Outpatient Colonoscopy Preparation
Condition(s):ColonoscopyLast Updated:September 4, 2012Completed
21
Placebo-controlled Trial of F-627 in Women With Breast Cancer Receiving Myelotoxic Chemotherapy
Condition(s):Breast Cancer; NeutropeniaLast Updated:March 25, 2019Completed
22
Phase 3 Study to Evaluate the Efficacy and Safety of Elafibranor Versus Placebo in Patients With Nonalcoholic Steatohepatitis (NASH)
Condition(s):Nonalcoholic Steatohepatitis (NASH) With FibrosisLast Updated:March 29, 2019Recruiting
23
A Randomized Double-Blind, Multi-Dose, Placebo Controlled Study of Acetaminophen Injection Post Surgical Dental Pain
Condition(s):Pain, Postoperative; Dental PainLast Updated:July 11, 2019Recruiting
24
A Study to Investigate the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome
Condition(s):Lennox Gastaut SyndromeLast Updated:September 5, 2019Recruiting
25
Tetracaine Compared to Placebo for Reducing Pain With Palivizumab – A Pilot Study
Condition(s):PainLast Updated:May 22, 2015Completed
26
The Efficacy of Gliatiline® on Post-stroke Patients With Vascular Cognitive Impairment no Dementia
Condition(s):Cognitive Impairment; StrokeLast Updated:October 11, 2013Completed
27
To Assess Effects of Arbaclofen ER Tablets Compared With Placebo on Sperm Parameters in Male Subjects With MS
Condition(s):Multiple Sclerosis; SpermLast Updated:August 28, 2019Withdrawn
28
A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH
Condition(s):Fatty LiverLast Updated:June 25, 2018Completed
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The Effect of 12-Week Dietary Intake of Lutein on Minimal Erythema Dose and Other Skin Parameters
Condition(s):Minimal Erythema Dose; Skin Viscoelasticity; Dermis DensityLast Updated:August 30, 2019Completed
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Aramchol for HIV-associated Nonalcoholic Fatty Liver Disease and Lipodystrophy
Condition(s):Nonalcoholic Fatty Liver Disease; HIVLast Updated:July 29, 2019Completed
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A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.
Condition(s):Down SyndromeLast Updated:August 21, 2017Completed
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Back to Basics – Effects, Narratives and Routes of Administration of Open-label Placebo
Condition(s):Placebo Effect; Pain; ExpectancyLast Updated:July 25, 2017Completed
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Psychobiological Mechanisms of Placebo and Nocebo Effects in the Treatment of Chronic Back Pain
Condition(s):Chronic Lower Back Pain; Healthy Control SubjectsLast Updated:January 15, 2015Completed
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Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma
Condition(s):Malignant Pleural MesotheliomaLast Updated:January 26, 2017Terminated
35
Using Honest Placebos to Improve Pain Management in Hand Surgery Patients
Condition(s):Hand or Wrist SurgeryLast Updated:August 13, 2018Not yet recruiting
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The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo
Condition(s):Pulpitis – IrreversibleLast Updated:April 14, 2017Completed
37
Pembrolizumab in Combination With Epacadostat or Placebo in Cisplatin-ineligible Urothelial Carcinoma (KEYNOTE-672/ECHO-307)
Condition(s):UC (Urothelial Cancer)Last Updated:August 27, 2019Active, not recruiting
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Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever
Condition(s):Liver Failure; Liver Failure, Acute; Drug Induced Liver Injury; Prevention & Control; FeverLast Updated:March 3, 2015Withdrawn
39
Treatment of Graves’ Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study
Condition(s):Thyroid Eye Disease; Graves’ OrbitopathyLast Updated:March 1, 2019Active, not recruiting
40
Abaloparatide vs. Placebo in Postmenopausal Women Receiving Initial Spinal Fusion Surgery
Condition(s):Spinal FusionLast Updated:August 15, 2019Not yet recruiting
41
NEM® Versus Placebo in Exercised-induced Joint Pain, Stiffness, & Cartilage Turnover in Healthy Men & Women
Condition(s):Exercise-induced Joint Pain; Exercise-induced Joint Stiffness; Exercise-induced Joint Cartilage TurnoverLast Updated:December 7, 2018Completed
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Pembrolizumab + Epacadostat vs Pembrolizumab + Placebo in Recurrent or Progressive Metastatic Urothelial Carcinoma
Condition(s):UC (Urothelial Cancer)Last Updated:August 14, 2019Active, not recruiting
43
Zinc for the Treatment of Herpes Simplex Labialis (HSL)
Condition(s):Herpes Simplex LabialisLast Updated:November 19, 2013Completed
44
Trust Game and Placebo Response
Condition(s):Placebo Effect; Pain; TrustLast Updated:April 7, 2016Completed
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Placebo Controlled Trial of SOM230 for the Reduction of Post-Pancreatectomy Fistula, Leak, and Abscess
Condition(s):Pancreatic CancerLast Updated:December 22, 2015Completed
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The Effects of Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops Compared to Placebo
Condition(s):Allergic Rhinitis; Allergic ConjunctivitisLast Updated:November 18, 2011Completed
47
Safety of Intravenous Acetaminophen Vs Placebo for the Treatment of Endotoxin-Induced Fever in Healthy Adult Males
Condition(s):FeverLast Updated:October 18, 2016Completed
48
Imaging Study to Compare Effects of Darolutamide and Enzalutamide With Respect to Placebo on the Blood Flow in the Brain in Healthy Male Volunteers.
Condition(s):Cerebrovascular CirculationLast Updated:October 7, 2019Active, not recruiting
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A Phase 3/4 Clinical Study to Evaluate the Efficacy and Safety of Aramchol Versus Placebo in Subjects With NASH (ARMOR)
Condition(s):Nonalcoholic Steatohepatitis (NASH)Last Updated:September 24, 2019Recruiting
50
A Clinical Trial to Compare the Efficacy and Safety of 1-week Treatment of Intravenous N-acetylcysteine (NAC) 600 mg Twice Daily, Ambroxol Hydrochloride 30 mg Twice Daily and Placebo as Expectorant Therapies in Adult Chinese Patients With Respiratory Tract Diseases and Abnormal Mucus Secretions
Condition(s):Respiratory Tract Diseases; Abnormal Mucus SecretionsLast Updated:September 16, 2019Recruiting
51
A Trial of Maintenance Treatment With Fluzoparib Versus Placebo in Relapsed Ovarian Cancer Patients
Condition(s):Ovarian CancerLast Updated:March 3, 2019Not yet recruiting
52
NEM® + BIOCURC® Versus Placebo in Exercised-induced Joint Pain, Stiffness, & Cartilage Turnover in Healthy Men & Women
Condition(s):Exercise-induced Joint Pain; Exercise-induced Joint Stiffness; Exercise-induced Joint Cartilage TurnoverLast Updated:July 16, 2019Completed
53
A Placebo Controlled Trial Of L-Tryptophan In Post-Operative Delirium
Condition(s):Post-operative DeliriumLast Updated:May 26, 2017Completed
54
CS02 vs Placebo With Metformin in Type 2 Diabetes Mellitus (T2DM)
Condition(s):T2DM With Inadequate Glycemic ControlLast Updated:April 18, 2019Recruiting
55
Neurobiological Underpinnings of Placebo Response in Depression
Condition(s):DepressionLast Updated:March 20, 2018Recruiting
56
The Effects of Oxytocin in Obese Adults
Condition(s):ObesityLast Updated:July 16, 2019Recruiting
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Effect of Acetazolamide on Lung Water Content by Ultrasound in Patients With Respiratory Disease at Altitude
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:October 29, 2018Recruiting
58
Trial of Maintenance SUO11248 Versus Placebo Post Chemotherapy for Patients With Advanced Urothelial Carcinoma
Condition(s):Bladder CancerLast Updated:November 7, 2014Terminated
59
NEM® Versus Placebo on Exercise-induced Joint Pain, Stiffness, & Cartilage Turnover In Healthy, Post-Menopausal Women
Condition(s):Exercise-induced Joint Pain Stiffness and Cartilage TurnoverLast Updated:August 15, 2018Completed
60
Oral Prednisone Taper Versus Placebo for the Treatment of Acute Relapses in Multiple Sclerosis
Condition(s):Multiple SclerosisLast Updated:December 17, 2015Terminated
61
Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer
Condition(s):Rectal CancerLast Updated:February 25, 2019Active, not recruiting
62
Arbaclofen in Children and Adolescents With ASD
Condition(s):Autism Spectrum DisorderLast Updated:October 16, 2019Recruiting
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Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu
Condition(s):ColdLast Updated:July 3, 2019Suspended
64
Pain Response to Open Label Placebo in Induced Acute Pain in Healthy Male Adults
Condition(s):Acute PainLast Updated:May 15, 2018Completed
65
Treatment of Bacterial Conjunctivitis With SHP640 Compared to PVP-Iodine and Placebo
Condition(s):Bacterial ConjunctivitisLast Updated:November 12, 2018Completed
66
Antidepressant Plus Asenapine Versus Antidepressant Plus Placebo for Depression
Condition(s):Major Depressive Disorder Without Psychotic FeaturesLast Updated:August 31, 2015Completed
67
Compare the Properties and Characteristics of an Investigational Formulation of Lamotrigine With Placebo
Condition(s):Mental DisordersLast Updated:August 1, 2017Completed
68
Therapeutic Potential for Intranasal Levodopa in Parkinson’s Disease -Off Reversal
Condition(s):Parkinson’s DiseaseLast Updated:June 17, 2019Completed
69
A Placebo-Controlled Study of Physiologic Effects of L-methylfolate in Schizophrenia Patients
Condition(s):SchizophreniaLast Updated:August 2, 2016Completed
70
Efficacy of Quetiapine XR Versus Placebo as Concomitant Treatment to Mood Stabilizers in the Control of Subsyndromal Symptoms of Bipolar Disorder
Condition(s):Bipolar DisorderLast Updated:September 18, 2012Completed
71
A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in Adolescents
Condition(s):Meningococcal MeningitisLast Updated:January 21, 2014Completed
72
A Study of the Safety and Efficacy of Fabrazyme (Agalsidase Beta) as Compared to Placebo in Patients With Advanced Fabry Disease
Condition(s):Fabry DiseaseLast Updated:December 2, 2013Completed
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A Study to Assess the Effects of PT003 and Placebo MDI on Specific Image Based Airway Volumes and Resistance in Subjects With Moderate to Severe COPD
Condition(s):COPDLast Updated:February 22, 2019Completed
74
A Phase 2, Multicentre, Randomized, Double-blind, Placebo-controlled Study in Patients With New-onset Type 1 Diabetes
Condition(s):Diabetes Mellitus, Insulin-DependentLast Updated:June 7, 2019Active, not recruiting
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Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Patients With Familial Dysbetalipoproteinemia
Condition(s):Familial Dysbetalipoproteinemia; Hyperlipoproteinemia Type IIILast Updated:January 17, 2019Not yet recruiting
76
A Randomised, Double-blind, Placebo Controlled Study With Oralgen Grass Pollen Rhinoconjunctivitis
Condition(s):Allergic RhinoconjunctivitisLast Updated:April 29, 2010Unknown status
77
A Study of Sintilimab or Placebo in Combination With Chemotherapy as Second-line Treatment for Patients With Stage IV Nonsquamous Non-small Cell Lung Cancer With Wild-type EGFR After Failure With Platinum-Containing Chemotherapy.
Condition(s):Nonsquamous Non-Small Cell Lung CancerLast Updated:June 19, 2019Recruiting
78
Efficacy of Eductyl® Versus Placebo for Treatment of Dyschesia
Condition(s):DyschesiaLast Updated:March 18, 2014Completed
79
Low Exhaled NO and ICS in Suspected Asthma
Condition(s):AsthmaLast Updated:May 12, 2016Unknown status
80
Double-Blind Comparison of the Efficacy and Safety of C213 to Placebo for the Acute Treatment of Cluster Headaches
Condition(s):Cluster HeadacheLast Updated:October 14, 2019Recruiting
81
Effect of Curodont Repair or Placebo on the Remineralisation in Patients With Class 5 Carious Lesions
Condition(s):Dental CariesLast Updated:August 28, 2019Completed
82
Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis
Condition(s):Lupus NephritisLast Updated:October 7, 2019Active, not recruiting
83
Assessment of Effects on Ovarian Activity of a Combined Oral Contraceptive Pill When Preceded by the Intake of ellaOne® or Placebo.
Condition(s):Emergency ContraceptionLast Updated:June 12, 2013Completed
84
A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis
Condition(s):Osteoarthritis of the KneeLast Updated:February 5, 2018Completed
85
CARAT: Canagliflozin vs. Placebo for Post Bariatric Patients With Persistent Type 2 Diabetes
Condition(s):Diabetes Mellitus, Type 2; ObesityLast Updated:March 1, 2019Terminated
86
A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)
Condition(s):Prurigo NodularisLast Updated:February 27, 2018Completed
87
Evaluation of Major Cardiovascular Events in Patients With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo
Condition(s):Cardiovascular Diseases; Statin Adverse ReactionLast Updated:June 28, 2019Recruiting
88
A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-935 (OV935) as an Adjunctive Therapy in Pediatric Patients With Developmental and/or Epileptic Encephalopathies
Condition(s):Epilepsy; Dravet Syndrome; Lennox-Gastaut SyndromeLast Updated:October 5, 2019Recruiting
89
Comparing 4.0 mg.Kg-1 Sugammadex With Placebo in the Reversal of Profound Neuromuscular Blockade (P05767)
Condition(s):Anesthesia; Neuromuscular BlockadeLast Updated:August 4, 2015Completed
90
Sugammadex Efficacy and Safety for Reversal of Pipecuronium-induced Neuromuscular Blockade
Condition(s):Adult Subjects Undergoing Abdominal Surgery Under General AnesthesiaLast Updated:August 26, 2011Unknown status
91
Effects of Testosterone Undecanoate vs Placebo on Intrahepatic Fat Content in Obese Men With T2DM and Hypogonadism
Condition(s):Fatty Liver; Obesity; Type2 Diabetes Mellitus; Hypogonadism, MaleLast Updated:February 21, 2019Not yet recruiting
92
A Phase 3, Randomized, Three-Cycle, Double-Blind, Placebo-Controlled Study to Evaluate Induction of Secretory Conversion of Endometrium and Withdrawal Bleeding for Secondary Amenorrhea
Condition(s):Secondary AmenorrheaLast Updated:May 3, 2018Terminated
93
A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV
Condition(s):HIV DementiaLast Updated:May 14, 2012Unknown status
94
Can Oxytocin Enhance the Placebo Effect?
Condition(s):Oxytocin Effect on Memory Performance During Phase 1; Oxytocin Effect on Memory Performance During Phase 2; Oxytocin Effect on Memory Performance During Phase 3; Oxytocin Effect on Memory Performance During Phase 4Last Updated:October 10, 2018Completed
95
Study to Compare Triple Therapy (Oral Treprostinil, Ambrisentan, and Tadalafil) With Dual Therapy (Ambrisentan, Tadalafil, and Placebo) in Subjects With Pulmonary Arterial Hypertension
Condition(s):Pulmonary Arterial HypertensionLast Updated:October 31, 2017Withdrawn
96
Safety and Efficacy of tocilizuMAb Versus Placebo in Polymyalgia rHeumatica With glucocORticoid dEpendence SEMAPHORE
Condition(s):Polymyalgia RheumaticaLast Updated:June 12, 2019Recruiting
97
Citalopram to Enhance Cognition in HD
Condition(s):Huntington Disease; Chorea; Executive DysfunctionLast Updated:February 8, 2013Completed
98
SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis
Condition(s):Relapsing Remitting Multiple Sclerosis; Primary Progressive Multiple Sclerosis; Secondary Progressive Multiple SclerosisLast Updated:January 9, 2019Not yet recruiting
99
Comparison of Indacaterol With That of Placebo in ‘Maintenance naïve’ Patients With COPD Using Blinded Tiotropium as Active Control
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:April 19, 2017Withdrawn
100
SER-262 Versus Placebo in Adults With Primary Clostridium Difficile Infection to Prevent Recurrence
Condition(s):Clostridium Difficile InfectionLast Updated:April 18, 2018Active, not recruiting