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Evolution and Risk Factors Associated With Geographic Atrophy Progression
Condition(s):Geographic AtrophyLast Updated:March 23, 2015Completed
Geographic Atrophy: 139 Clinical Trials, Page 1 of 2
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A Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:September 23, 2019Completed
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Geographic Atrophy and Intravitreal Ranibizumab Injections
Condition(s):Age-related Macular Degeneration; Geographic AtrophyLast Updated:February 25, 2015Unknown status
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Clinical Study to Evaluate Treatment With ORACEA® for Geographic Atrophy (TOGA)
Condition(s):Geographic AtrophyLast Updated:October 9, 2018Active, not recruiting
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CLG561 Proof-of-Concept Study as a Monotherapy and in Combination With LFG316 in Subjects With Geographic Atrophy (GA)
Condition(s):Geographic AtrophyLast Updated:May 17, 2019Completed
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Zimura in Subjects With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration
Condition(s):Geographic Atrophy; Macular DegenerationLast Updated:November 8, 2018Active, not recruiting
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A Study of Disease Progression in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Condition(s):Geographic AtrophyLast Updated:August 16, 2019Terminated
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A Study of Disease Progression in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Condition(s):Geographic AtrophyLast Updated:August 7, 2019Terminated
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A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)
Condition(s):Macular Degeneration; Geographic AtrophyLast Updated:October 29, 2019Recruiting
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Study of of APL-2 Therapy in Patients Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:December 18, 2017Completed
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Intravitreal Injections of Sirolimus in the Treatment of Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:December 8, 2015Terminated
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A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Condition(s):Geographic AtrophyLast Updated:June 17, 2019Terminated
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A Study of Safety, Tolerability, and Evidence of Activity of FCFD4514S Administered Monthly or Every Other Month to Patients With Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:November 1, 2016Completed
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Study of NGM621 in Participants With Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:September 30, 2019Recruiting
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Study to Evaluate the Safety of Intravitreal APL-2 in Patients Diagnosed With Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:December 20, 2018Active, not recruiting
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A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular Degeneration
Condition(s):Geographic Atrophy; Macular DegenerationLast Updated:March 29, 2019Terminated
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A Multicenter, Proof-Of-Concept Study Of Intravitreal AL-78898A In Patients With Geographic Atrophy (GA) Associated With Age-Related Macular Degeneration (AMD)
Condition(s):Geographic AtrophyLast Updated:December 3, 2013Terminated
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Safety and Efficacy of IONIS-FB-Lrx in up to 120 Patients 55 and Older With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Condition(s):Geographic Atrophy; Age Related Macular DegenerationLast Updated:August 9, 2019Withdrawn
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Micropulse Laser for Geographic Atrophy
Condition(s):Geographic Atrophy; Age-related Macular DegenerationLast Updated:September 16, 2019Completed
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Subthreshold Laser Treatment for Reticular Pseudodrusen and Geographic Atrophy Secondary to AMD
Condition(s):Age-Related Macular Degeneration; Geographic Atrophy; Reticular PseudodrusenLast Updated:July 29, 2019Recruiting
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Carbidopa-Levodopa in Dry AMD With Geographic Atrophy
Condition(s):Age Related Macular DegenerationLast Updated:September 17, 2019Active, not recruiting
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Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD
Condition(s):Age-Related Macular Degeneration; Macular Degeneration, Age-Related; Dry Macular Degeneration; Geographic AtrophyLast Updated:January 25, 2019Recruiting
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A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Condition(s):Geographic AtrophyLast Updated:October 14, 2019Terminated
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Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE)
Condition(s):Age Related Macular Degeneration; Geographic AtrophyLast Updated:December 17, 2013Completed
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An Extension Study to Evaluate the Long-Term Safety of Lampalizumab in Participants With Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:September 10, 2019Terminated
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Geographic Atrophy Treatment Evaluation
Condition(s):Geographic Atrophy; Age-Related Macular DegenerationLast Updated:June 4, 2014Terminated
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A Phase I Open Label Dose Escalation Trial of RNA-144101 in the Treatment of Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:January 15, 2018Withdrawn
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Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration
Condition(s):Geographic Atrophy; Dry Age Related Macular DegenerationLast Updated:June 21, 2010Completed
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Safety and Efficacy of Brimonidine Intravitreal Implant in Patients With Geographic Atrophy Due to Age-related Macular Degeneration (AMD)
Condition(s):Macular DegenerationLast Updated:July 24, 2018Completed
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A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD Patients
Condition(s):Age-Related Macular DegenerationLast Updated:February 28, 2019Completed
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A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Intravitreal Injections of FCFD4514S in Patients With Geographic Atrophy
Condition(s):Geographic AtrophyLast Updated:February 2, 2012Completed
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A Study Assessing the Safety, Tolerability, and Efficacy of RO7171009 in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)
Condition(s):Macular Degeneration, Age-Related; Geographic AtrophyLast Updated:October 30, 2019Recruiting
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OT-551 Antioxidant Eye Drops to Treat Geographic Atrophy in Age-Related Macular Degeneration
Condition(s):Geographic Atrophy; Age-Related Macular Degeneration; AMDLast Updated:August 16, 2011Completed
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Fluocinolone Acetonide Intravitreal Inserts in Geographic Atrophy
Condition(s):Age-Related Macular DegenerationLast Updated:May 11, 2015Terminated
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Pharmacokinetic and Pharmacodynamic Study of Emixustat in Subjects With Geographic Atrophy Associated With Dry Age-Related Macular Degeneration
Condition(s):Geographic Atrophy; Age-Related Macular DegenerationLast Updated:January 14, 2016Completed
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Directional Spread in Geographic Atrophy
Condition(s):Nonexudative Age-related Macular DegenerationLast Updated:April 30, 2019Recruiting
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Sparing of the Fovea in Geographic Atrophy Progression
Condition(s):Atrophy; Geographic Atrophy; Age-related Macular Degeneration; Eye DiseasesLast Updated:May 5, 2017Completed
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Long-Term Follow-up Safety Study of Human Central Nervous System Stem Cells in Subjects With Geographic Atrophy of Age-Related Macular Degeneration
Condition(s):Age-Related Macular Degeneration; Geographic AtrophyLast Updated:May 31, 2016Terminated
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Complement Inhibition With Eculizumab for the Treatment of Non-Exudative Macular Degeneration (AMD)
Condition(s):Age-Related Macular DegenerationLast Updated:April 29, 2017Completed
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Efficacy, Safety And Tolerability Study Of RN6G In Subjects With Geographic Atrophy Secondary to Age-related Macular Degeneration
Condition(s):Age-Related MaculopathyLast Updated:February 16, 2016Terminated
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Efficacy and Safety Study of CNTO 2476 in Participants With Visual Acuity Impairment Associated With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD)
Condition(s):Visual Acuity; Geographic Atrophy; Macular DegenerationLast Updated:December 21, 2017Withdrawn
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Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration
Condition(s):Geographic AtrophyLast Updated:September 11, 2019Recruiting
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Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACU-4429 in Subjects With Geographic Atrophy
Condition(s):Dry Age-related Macular Degeneration; Geographic AtrophyLast Updated:February 7, 2014Completed
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Safety and Tolerability Study of RO7171009 in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Condition(s):Geographic AtrophyLast Updated:February 12, 2019Completed
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Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)
Condition(s):Geographic AtrophyLast Updated:February 19, 2019Terminated
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Safety and Efficacy Assessment Treatment Trials of Emixustat Hydrochloride
Condition(s):Geographic AtrophyLast Updated:June 26, 2017Completed
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A Study to Evaluate the Safety and Clinical Response of Subretinal Administration of CNTO 2476 in Participants With Geographic Atrophy
Condition(s):Visual Acuity; Geographic Atrophy; Macular DegenerationLast Updated:August 13, 2019Completed
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Sirolimus for Advanced Age-Related Macular Degeneration
Condition(s):Age-Related Macular Degeneration; Geographic AtrophyLast Updated:May 15, 2014Completed
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Clinical Study to Investigate Safety and Efficacy of GSK933776 in Adult Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration
Condition(s):Atrophy, GeographicLast Updated:March 27, 2017Completed
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Phase 3 Study of ALK-001 in Geographic Atrophy
Condition(s):Geographic Atrophy; Age Related Macular Degeneration; AMD; Atrophy, GeographicLast Updated:June 11, 2019Recruiting
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Measuring Geographic Atrophy in AMD Patients Using the Nidek MP-3 Microperimetry Device
Condition(s):Age-related Macular Degeneration (AMD)Last Updated:February 12, 2019Completed
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The Natural History of Geographic Atrophy Progression (GAP) Study
Condition(s):Age-Related Macular Degeneration; Geographic AtrophyLast Updated:February 26, 2010Terminated
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Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration
Condition(s):Age- Related Macular DegenerationLast Updated:November 7, 2019Recruiting
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Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration
Condition(s):Age-Related Macular DegenerationLast Updated:October 3, 2019Recruiting
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The OMEGA Study: Use of Eye Drops to Treat Geographic Atrophy Associated With Age-Related Macular Degeneration (Dry AMD)
Condition(s):Age-Related Macular DegenerationLast Updated:March 31, 2008Unknown status
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Alpha Lipoic Acid in Geographic Atrophy
Condition(s):Age-Related Macular DegenerationLast Updated:August 12, 2019Completed
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Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD)
Condition(s):Geographic Atrophy; Age-related Macular DegenerationLast Updated:March 29, 2019Completed
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Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral GA Associated With AMD
Condition(s):Age-Related Macular DegenerationLast Updated:April 7, 2014Completed
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Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic Atrophy
Condition(s):Age-Related Maculopathy; Age-Related Maculopathies; Eye Diseases; Retinal Degeneration; Macular DegenerationLast Updated:March 27, 2013Completed
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This is a 30-month, Phase III, Multicenter, Randomized, Double-masked, Sham-injection Controlled Study to Assess the Efficacy and Safety of Multiple IVT Injections of APL-2 in Subjects With GA Secondary to AMD
Condition(s):Geographic AtrophyLast Updated:September 12, 2019Recruiting
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Study to Assess the Safety and Effects of Cells Injected Intravitreal in Dry Macular Degeneration
Condition(s):Dry Macular DegenerationLast Updated:September 15, 2015Withdrawn
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Repeatability and Reproducibility of Cirrus HD-OCT Measurements of Illumination Areas Under the Retinal Pigment Epithelium
Condition(s):Advanced Dry AMD With Geographic AtrophyLast Updated:June 27, 2013Completed
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A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy
Condition(s):Macular DegenerationLast Updated:November 11, 2019Recruiting
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A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degeneration
Condition(s):Age-related Macular DegenerationLast Updated:August 1, 2017Completed
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ReCLAIM-2 Study to Evaluate Safety,Efficacy & Pharmacokinetics of Elamipretide in Subjects With AMD With Non-central GA
Condition(s):Age-related Macular DegenerationLast Updated:November 12, 2019Recruiting
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A Clinical Trial Designed To Evaluate The Safety And Exploratory Efficacy Of 1.0 Mg Luminate® (Alg-1001) As A Treatment For Non-Exudative Macular Degeneration
Condition(s):Dry Age-related Macular DegenerationLast Updated:July 8, 2019Active, not recruiting
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Therapeutic Potential of Omega-3 Fatty Acids Supplementation in Dry Macular Degeneration and Stargardt Disease
Condition(s):Dry AMD; Stargardt Disease 1Last Updated:November 4, 2019Recruiting
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Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration (AMD)
Condition(s):Age Related Macular Degeneration; Macular Degeneration; AMDLast Updated:September 10, 2015Completed
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Study of Subretinal Implantation of Human Embryonic Stem Cell-Derived RPE Cells in Advanced Dry AMD
Condition(s):Dry Macular Degeneration; Geographic AtrophyLast Updated:September 9, 2019Active, not recruiting
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Treatment of Advanced Dry Age Related Macular Degeneration With AAVCAGsCD59
Condition(s):Dry Age-related Macular DegenerationLast Updated:March 4, 2019Active, not recruiting
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Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular Degeneration
Condition(s):Age-related Macular DegenerationLast Updated:November 12, 2019Recruiting
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Alpha MSH in Ocular Disease
Condition(s):Advanced Dry Macular DegenerationLast Updated:February 26, 2019Recruiting
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Global Atrophie Biomarker Evaluation Study (GABiE)
Condition(s):Age-related Macular DegenerationLast Updated:November 4, 2019Recruiting
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To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)
Condition(s):Dry Age-related Macular Degeneration; Macular Degeneration; Retinal Disease; Retinal Degeneration; Geographic Atrophy; Macular AtrophyLast Updated:October 23, 2019Recruiting
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BioCurrent Electrical Stimulation for the Treatment of Dry ARMD
Condition(s):Dry Macular DegenerationLast Updated:June 2, 2018Withdrawn
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Objective Assessment of Macular Function at Retinal and Cortical Levels
Condition(s):Macula; Degeneration, Congenital or Hereditary; Retina DisorderLast Updated:May 3, 2018Not yet recruiting
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Non Exudative AMD Imaged With SS-OCT
Condition(s):Dry Macular DegenerationLast Updated:January 14, 2019Recruiting
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Non-Damaging Photothermal Therapy of Non-exudative Age Related Macular Degeneration
Condition(s):Macular Degeneration; Retinal DrusenLast Updated:November 6, 2018Active, not recruiting
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Non-exudative Age-related Macular Degeneration
Condition(s):Non-exudative Age-related Macular DegenerationLast Updated:April 3, 2018Completed
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Fundus Autofluorescence Imaging in Age-related Macular Degeneration Using Confocal Scanning Laser Ophthalmoscopy
Condition(s):Age-related Macular DegenerationLast Updated:October 10, 2018Completed
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Omega 6:Omega 3 Ratio and Progression of Age-related Macular Degeneration (AMD).
Condition(s):Age-related Macular DegenerationLast Updated:January 4, 2015Terminated
82
Study of HUCNS-SC Subretinal Transplantation in Subjects With GA of AMD
Condition(s):Age-Related Macular DegenerationLast Updated:May 31, 2016Terminated
83
Selective RPE Laser Treatment (SRT) for Various Macular Diseases
Condition(s):Age-Related Macular Degeneration; Diabetic Maculopathy; Central Serous ChorioretinopathyLast Updated:January 11, 2010Unknown status
84
Research With Retinal Cells Derived From Stem Cells for Myopic Macular Degeneration
Condition(s):Myopic Macular DegenerationLast Updated:July 14, 2016Withdrawn
85
Pharmacokinetic (PK) Study of GSK933776 in Healthy Volunteers
Condition(s):Atrophy, GeographicLast Updated:May 12, 2017Completed
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A Population-based Study of Macular Choroidal Neovascularization in a Chinese Population
Condition(s):Geographic Atrophy; Wet Macular Degeneration; Retinal DrusenLast Updated:August 14, 2012Completed
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Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular Degeneration
Condition(s):Age Related Macular DegenerationLast Updated:December 20, 2013Unknown status
88
A Study of ARC1905 (Anti-C5 Aptamer) in Subjects With Dry Age-related Macular Degeneration
Condition(s):Age-Related Macular DegenerationLast Updated:August 23, 2017Completed
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Safety and Tolerability of Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients With Advanced Dry Age Related Macular Degeneration
Condition(s):Dry Age Related Macular DegenerationLast Updated:February 17, 2017Completed
90
An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration
Condition(s):Age-Related Macular DegenerationLast Updated:September 5, 2017Unknown status
91
PreView PHP Preferential Hyperacuity Perimeter for the Detection of Choroidal Neovascularization
Condition(s):Age Related Macular DegenerationLast Updated:January 10, 2008Completed
92
First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD
Condition(s):Dry Age-related Macular Degeneration; Macular Degeneration; Retinal Disease; Eye Diseases; Retinal Degeneration; Geographic Atrophy; Macular AtrophyLast Updated:July 8, 2019Recruiting
93
Morpho-functional Changes After Oral Supplementation of Antioxidants and Anti-inflammatory Treatment in Age-Related Macular Degeneration.
Condition(s):Dry AMDLast Updated:May 7, 2019Completed
94
Reticular Pseudodrusen Progression Study
Condition(s):Age-related Macular DegenerationLast Updated:January 19, 2015Unknown status
95
Visual Rehabilitation Through Acoustic Biofeedback With Retimax Vision Trainer in Patients With Advanced Age-related Macular Degeneration
Condition(s):Macular Degeneration Advanced; Macular Degeneration, Senile; Macular Degeneration, Dry; Macular Scar; Macular Degeneration NonexudativeLast Updated:September 9, 2019Completed
96
Correlation Between Visual Acuity Measurements, Quality of Life and Morphological Parameters in Wet AMD Patients
Condition(s):Macular DegenerationLast Updated:February 12, 2018Completed
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Risk Factors for Drusen Progression
Condition(s):Age-related Macular DegenerationLast Updated:April 7, 2015Withdrawn
98
TTT Versus PDT for Treatment of Choroidal Neovascularization in Age-Related Macular Degeneration
Condition(s):Choroidal NeovascularizationLast Updated:February 2, 2006Unknown status
99
Safety and Effectiveness Investigation for Dry, Non-Exudative Age Related Macular Degeneration (AMD) Using Rheopheresis
Condition(s):Age-Related MaculopathyLast Updated:November 6, 2007Suspended
100
Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Patients With AMD
Condition(s):Age-Related Macular DegenerationLast Updated:October 30, 2019Completed