First in Human: 7227 Clinical Trials, Page 30 of 723

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A First-in-human Study of the Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of SAR439459 Monotherapy and Combination of SAR439459 and Cemiplimab in Patients With Advanced Solid Tumors

Condition(s):Malignant Solid TumorLast Updated:May 12, 2022Terminated

First in Human Study of ALS-002200; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1

Condition(s):Hepatitis C, ChronicLast Updated:October 31, 2017Completed

First in Human Study of ALS-002158; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1

Condition(s):Hepatitis C, ChronicLast Updated:October 31, 2017Terminated

A Phase 1/2, First-in-Human, Open-Label, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/Metastatic MAGE-A1+ Solid Tumors

Condition(s):Advanced Solid TumorsLast Updated:August 19, 2022Recruiting

A First-In-Human Study of Orally Administered JNJ-64417184 to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses, and the Antiviral Activity of Multiple Doses in a Respiratory Syncytial Virus (RSV) Challenge Study in Healthy Participants

Condition(s):HealthyLast Updated:January 29, 2020Completed

First In Human Study To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of PF-04427429 Administered Intravenously To Healthy Adult Volunteers

Condition(s):Healthy VolunteersLast Updated:December 4, 2018Completed

A Phase I, Double Blind, Placebo Controlled, First in Human, Single and Multiple Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study in Healthy Male and Female Subjects

Condition(s):Parkinson’s DiseaseLast Updated:September 28, 2016Completed

A Phase 1, First-in-human, Double-blinded, Randomized, Placebo-controlled Trial of a Zika Virus Purified Inactivated Vaccine (ZPIV) With Alum Adjuvant in Healthy Flavivirus-naive and Flavivirus-Primed Subjects.

Condition(s):Zika Virus InfectionLast Updated:September 7, 2020Completed

First in Human Study to Evaluate AZD8205 in Patients With Advanced or Metastatic Solid Malignancies

Condition(s):Breast Cancer; Cholangiocarcinoma; Ovarian Cancer; Endometrial CancerLast Updated:November 1, 2022Recruiting

Phase I/II, First in Human, Dose Escalation Trial of TL-895 in Subjects With R/R CLL/SLL and Expansion in Treatment Naïve CLL/SLL Subjects and Subjects With R/R CLL/SLL

Condition(s):Relapsed/Refractory B Cell Malignancies; Mantle Cell Lymphoma and Diffuse Large B Cell Lymphoma; Chronic Lymphocytic Leukemia; Small Lymphocytic LymphomaLast Updated:October 12, 2022Active, not recruiting

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