1
Treatment of REM Sleep Behavior Disorder (RBD) With Sodium Oxybate
Condition(s):REM Sleep Behavior DisorderLast Updated:September 17, 2019Recruiting
SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Sodium Oxybate as an Intervention: 45 Clinical Trials
Hide Studies Not Open or Pending
2
Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor
Condition(s):Spasmodic Dysphonia; Voice Tremor; Vocal Fold NodulesLast Updated:January 4, 2019Recruiting
3
Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine Changes
Condition(s):Narcolepsy With CataplexyLast Updated:June 18, 2015Completed
4
Study of the Symptomatic Effects of Nocturnal Sodium Oxybate in Parkinson’s Disease
Condition(s):Sleep-wake Disturbances in Motor-phase Parkinson`s DiseaseLast Updated:April 8, 2014Unknown status
5
Sodium Oxybate in Schizophrenia With Insomnia
Condition(s):Schizophrenia; Insomnia Related to Schizophrenia (307.42)Last Updated:January 5, 2016Completed
6
Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response
Condition(s):Spasmodic Dysphonia; Voice TremorLast Updated:October 26, 2017Completed
7
Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traumatic Hypersomnia
Condition(s):Hypersomnia; Narcolepsy; Traumatic Brain InjuryLast Updated:August 16, 2019Recruiting
8
Sodium Oxybate in Patients With Alternating Hemiplegia of Childhood (AHC-SO)
Condition(s):Alternating Hemiplegia of ChildhoodLast Updated:March 3, 2014Completed
9
Enhancing Slow Wave Sleep With Sodium Oxybate
Condition(s):SleepLast Updated:September 25, 2008Completed
10
Trial of Xyrem for Excessive Daytime Sleepiness and Sleep Disturbance in Parkinson’s Disease (PD)
Condition(s):Parkinson DiseaseLast Updated:April 30, 2009Completed
11
Sodium Oxybate in Patients With Episodic and Chronic Cluster Headache
Condition(s):Cluster HeadacheLast Updated:December 18, 2015Unknown status
12
Xyrem and Brain Dopamine in Narcolepsy
Condition(s):Narcolepsy With CataplexyLast Updated:July 30, 2019Recruiting
13
Sodium Oxybate in Idiopathic Hypersomnia
Condition(s):Idiopathic HypersomniaLast Updated:May 16, 2019Recruiting
14
Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy
Condition(s):Excessive Daytime Sleepiness; Cataplexy; NarcolepsyLast Updated:September 25, 2019Recruiting
15
The Effect of Sodium Oxybate on Sleep Architecture
Condition(s):Mechanically Ventilated ICU PatientsLast Updated:February 21, 2018Withdrawn
16
Sodium Oxybate in Patients With Chronic Fatigue Syndrome.
Condition(s):Chronic Fatigue SyndromeLast Updated:December 4, 2014Unknown status
17
Use of Xyrem to Improve Sleep in Chronic Fatigue Syndrome
Condition(s):Chronic Fatigue SyndromeLast Updated:May 18, 2016Terminated
18
SWS And Daytime Functioning in Chronic FatiguE Syndrome (SAFFE)
Condition(s):Chronic Fatigue SyndromeLast Updated:August 26, 2015Completed
19
Safety and Feasibility of Sodium Oxybate in Mild Alzheimer’s Disease Patients
Condition(s):Mild Alzheimer’s DiseaseLast Updated:July 6, 2010Terminated
20
A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics
Condition(s):Narcolepsy, Excessive Daytime SleepinessLast Updated:May 28, 2015Completed
21
Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.
Condition(s):Sleep Initiation and Maintenance DisordersLast Updated:April 26, 2017Completed
22
Trial of Xyrem® (Sodium Oxybate) for the Treatment of Narcolepsy
Condition(s):NarcolepsyLast Updated:September 18, 2013Completed
23
Safety and Efficacy of Xyrem Oral Solution (Sodium Oxybate) Compared With Placebo in Narcoleptic Patients
Condition(s):NarcolepsyLast Updated:June 23, 2005Completed
24
Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction
Condition(s):Amyloid-betaLast Updated:March 26, 2018Completed
25
Trial Comparing the Effects of Xyrem (Sodium Oxybate) With Placebo for the Treatment of Fibromyalgia
Condition(s):FibromyalgiaLast Updated:January 20, 2012Completed
26
Physiological, Behavioral and Subjective Effects of Drugs (GHB)
Condition(s):Sedative AbuseLast Updated:September 9, 2008Completed
27
A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy
Condition(s):Narcolepsy With CataplexyLast Updated:April 26, 2019Completed
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Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia.
Condition(s):FibromyalgiaLast Updated:March 28, 2012Completed
29
Sodium Oxybate in the Treatment of Binge Eating Disorder
Condition(s):Binge Eating DisorderLast Updated:June 21, 2011Completed
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Multiple-dose,Double-blind,Placebo-controlled Study of Sodium Oxybate in Patients With Essential Tremor
Condition(s):Essential TremorLast Updated:December 15, 2011Completed
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Xyrem for Treatment Refractory Insomnia Due to PTSD
Condition(s):PTSD; Anxiety, Post TraumaticLast Updated:September 6, 2012Withdrawn
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Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy
Condition(s):NarcolepsyLast Updated:December 21, 2011Completed
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Safety and Tolerability Study Comparing Sodium Oxybate Given as an Oral Solution to a Single-blinded Combination of Oral Tablets Plus Oral Solution in Subjects With Fibromyalgia
Condition(s):FibromyalgiaLast Updated:August 17, 2011Completed
34
A Safety and Efficacy Study of Xyrem® (Sodium Oxybate) to Treat Fibromyalgia.
Condition(s):FibromyalgiaLast Updated:January 20, 2012Completed
35
Characterization of the Prosocial and Prosexual Effects of GHB
Condition(s):Depressive Disorder, Major; Bipolar Disorder; Autistic DisorderLast Updated:July 25, 2019Completed
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Comparative Study of Gamma-hydroxy Butyrate Versus Oxazepam in the Treatment of Alcohol Withdrawal Syndrome
Condition(s):Alcohol Withdrawal Syndrome; Alcohol DependenceLast Updated:March 17, 2014Completed
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A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia
Condition(s):FibromyalgiaLast Updated:December 21, 2011Completed
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Trial of Effects of Oral Xyrem and Zolpidem on Sleep-Disordered Breathing in Obstructive Sleep Apnea Patients
Condition(s):Obstructive Sleep Apnea SyndromeLast Updated:January 20, 2012Completed
39
Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV)
Condition(s):NarcolepsyLast Updated:November 17, 2015Completed
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Observational Study to Evaluate Risks of Side Effects, Drug Abuse and Dependence in Patients Who Received Xyrem ® on Prescription
Condition(s):NarcolepsyLast Updated:September 5, 2016Completed
41
Memory Enhancement by Gamma-hydroxybutyrate vs. Trazodone in Major Depressive Disorder.
Condition(s):Major Depressive DisorderLast Updated:October 3, 2019Not yet recruiting
42
Memory Consolidation in Pharmacologically Enhanced Naps
Condition(s):SleepLast Updated:December 8, 2015Completed
43
The Efficacy and Security of the Small Stitch Technique in Emergency Surgery
Condition(s):Abdominal Wall Defect; Abdominal Wall Hernia; Eventration; Evisceration; Operation WoundLast Updated:December 4, 2018Recruiting
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Study of Phasix™ Mesh for VHWG Grade 3 Midline Hernia Repair
Condition(s):Hernia; Hernia, Abdominal; Hernia, IncisionalLast Updated:July 26, 2019Completed
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Utility of a Supraaponeurotic Mesh as Prophylaxis of the Midline Eventration After an Oncological Colorrectal Resection
Condition(s):EventrationLast Updated:August 12, 2019Recruiting