1
Empiric Quinidine for Asymptomatic Brugada Syndrome
Condition(s):ArrhythmiaLast Updated:January 7, 2019Active, not recruiting
Quinidine Gluconate as an Intervention: 57 Clinical Trials
Hide Studies Not Open or Pending
2
Safety and Pharmacokinetics of Quinidine Alone and in Combination With Dabigatran Etexilate
Condition(s):HealthyLast Updated:June 20, 2014Completed
3
Evaluating the Efficacy of Dextromethorphan/Quinidine in Treating Irritability in Huntington’s Disease
Condition(s):Huntington Disease; IrritabilityLast Updated:April 17, 2019Recruiting
4
A Study to Evaluate the Effect of Genotype on LY2216684
Condition(s):Depressive Disorder, MajorLast Updated:March 26, 2018Completed
5
Drug-drug Interaction Study Between EDP-305, Fluconazole and Quinidine in Healthy Volunteers
Condition(s):NASH – Nonalcoholic SteatohepatitisLast Updated:December 4, 2018Completed
6
Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118
Condition(s):Drug Induced ConstipationLast Updated:October 13, 2014Completed
7
Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Alzheimer’s Patients
Condition(s):Agitation; Alzheimer’s DiseaseLast Updated:January 8, 2018Completed
8
Relative Bioavailability of Dabigatran Etexilate Capsules With and Without Quinidine Sulfate Tablets and to Measure the Effect of Quinidine on the Absorption of Fexofenadine in Healthy Male and Female Volunteers
Condition(s):HealthyLast Updated:June 20, 2014Terminated
9
Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS
Condition(s):Pseudobulbar Affect (PBA)Last Updated:March 15, 2017Completed
10
Effectiveness, Safety, and Health-Related Outcomes of NUEDEXTA® in Nursing Home Patients With Pseudobulbar Affect (PBA)
Condition(s):Pseudobulbar Affect (Involuntary Laughing and/or Crying)Last Updated:June 6, 2017Terminated
11
Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants
Condition(s):Healthy Adult Male and Female VolunteersLast Updated:February 21, 2018Completed
12
Nuedexta in Treatment-Resistant Major Depression
Condition(s):Major Depressive Disorder; Treatment ResistantLast Updated:May 10, 2018Completed
13
Drug-Drug Interaction Study Between EDP-938, Itraconazole, Rifampin, and Quinidine in Healthy Subjects
Condition(s):RSV InfectionLast Updated:June 12, 2019Completed
14
Impact of Nuedexta on Bulbar Physiology and Function in ALS
Condition(s):Amyotrophic Lateral SclerosisLast Updated:October 19, 2019Recruiting
15
Study of the Electrocardiographic Effects of Ranolazine, Dofetilide, Verapamil, and Quinidine in Healthy Subjects
Condition(s):Drug-induced Surface ECG ChangesLast Updated:February 6, 2018Completed
16
Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer’s Type
Condition(s):Agitation in Patients With Dementia of the Alzheimer’s TypeLast Updated:November 26, 2019Recruiting
17
Nuedexta in the Treatment of Pseudobulbar Affect in Patients With Alzheimer’s Disease
Condition(s):Alzheimer’s Disease; Pseudobulbar Affect (PBA)Last Updated:October 25, 2019Terminated
18
Safety and Efficacy of AVP-923 in the Treatment of Levodopa-induced Dyskinesia in Parkinson’s Disease Patients
Condition(s):Dyskinesia; Parkinson’s DiseaseLast Updated:January 8, 2018Completed
19
Nuedexta for the Treatment of Adults With Autism
Condition(s):AutismLast Updated:November 4, 2017Completed
20
Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
Condition(s):Depressive Disorder, Treatment-ResistantLast Updated:May 11, 2017Completed
21
Nuedexta for the Prevention and Modification of Disease Progression in Episodic Migraine
Condition(s):Episodic MigraineLast Updated:March 5, 2018Completed
22
Safety and Efficacy of Dextromethorphan and Quinidine in the Treatment of the Pain of Diabetic Neuropathy
Condition(s):Pain; Diabetic NeuropathyLast Updated:July 13, 2016Completed
23
A Phase 1 Study Comparing AVP-786 With AVP-923
Condition(s):Healthy VolunteerLast Updated:July 10, 2015Completed
24
Effect of P-glycoprotein Inhibition on Lenalidomide Pharmacokinetics in Healthy Males
Condition(s):HealthyLast Updated:November 6, 2019Completed
25
A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers
Condition(s):HealthyLast Updated:June 24, 2014Completed
26
Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS
Condition(s):Amyotrophic Lateral SclerosisLast Updated:July 13, 2016Completed
27
Clinical Trial Nuedexta in Subjects With ALS
Condition(s):Amyotrophic Lateral Sclerosis (ALS)Last Updated:February 3, 2017Completed
28
Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA)
Condition(s):Pseudobulbar Affect (PBA); Stroke; Dementia; Traumatic Brain Injury (TBI)Last Updated:January 26, 2017Completed
29
Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis
Condition(s):Central Neuropathic Pain; Multiple SclerosisLast Updated:June 28, 2018Completed
30
A Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy Subjects
Condition(s):Drug-drug InteractionLast Updated:June 24, 2014Completed
31
Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition
Condition(s):Disinhibition SyndromeLast Updated:October 2, 2018Terminated
32
Safety and Efficacy Study of IV Artesunate to Treat Malaria
Condition(s):MalariaLast Updated:September 20, 2019Completed
33
A Pilot Study on Edoxaban for the Resolution of Left Atrial Thrombosis in Patients With Non-valvular Atrial Fibrillation
Condition(s):Atrial FibrillationLast Updated:April 17, 2019Recruiting
34
A Comparison of Antiarrhythmic Drug Therapy and Radio Frequency Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
Condition(s):Paroxysmal Atrial FibrillationLast Updated:February 21, 2012Completed
35
Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Negative Symptoms of Schizophrenia
Condition(s):SchizophreniaLast Updated:November 26, 2019Recruiting
36
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Intermittent Explosive Disorder
Condition(s):Intermittent Explosive DisorderLast Updated:January 29, 2019Terminated
37
Edoxaban for the Treatment of Coagulopathy in Patients With Active Cancer and Acute Ischemic Stroke: a Pilot Study. (ENCHASE Study)
Condition(s):Correction of Cancer-related Coagulopathy With Novel Oral Anticoagulant (Edoxaban)Last Updated:June 16, 2018Recruiting
38
Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer’s Type
Condition(s):Agitation in Patients With Dementia of the Alzheimer’s TypeLast Updated:November 26, 2019Recruiting
39
Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Residual Schizophrenia
Condition(s):SchizophreniaLast Updated:July 30, 2018Completed
40
Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer’s Type
Condition(s):Agitation in Patients With Dementia of the Alzheimer’s TypeLast Updated:March 4, 2019Completed
41
Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer’s Type
Condition(s):Agitation in Patients With Dementia of the Alzheimer’s TypeLast Updated:October 13, 2019Completed
42
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Patients With Traumatic Brain Injury
Condition(s):Neurobehavioral DisinhibitionLast Updated:November 26, 2019Recruiting
43
Hydroquinidine Versus Placebo in Patients With Brugada Syndrome
Condition(s):Brugada SyndromeLast Updated:November 21, 2014Terminated
44
Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)
Condition(s):Alzheimer’s Disease; Stroke; Parkinson’s Disease; Traumatic Brain InjuryLast Updated:July 13, 2016Completed
45
Drug Interaction Study Between AVP-923 and Itraconazole and Between AVP-786 and Itraconazole in Healthy Adult Subejcts
Condition(s):HealthyLast Updated:March 16, 2017Completed
46
Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)
Condition(s):Arrhythmia; Cardiovascular Diseases; Death, Sudden, Cardiac; Heart Diseases; Tachycardia, Ventricular; Ventricular Arrhythmia; Ventricular FibrillationLast Updated:January 19, 2016Completed
47
Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)
Condition(s):Arrhythmia; Atrial Fibrillation; Cardiovascular Diseases; Heart DiseasesLast Updated:March 24, 2016Completed
48
Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)
Condition(s):Arrhythmia; Cardiovascular Diseases; Heart Arrest; Heart Diseases; Myocardial Infarction; Ventricular FibrillationLast Updated:July 26, 2013Completed
49
Catheter Ablation vs Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial
Condition(s):Atrial Fibrillation; ArrhythmiaLast Updated:August 22, 2019Completed
50
COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE
Condition(s):Mild Cognitive Impairment; Dementia; Hypoxia; Hyperhomocysteinemia; Vitamin B 12 Deficiency; Iron Deficiency; Anemia; TBI; Neurodegenerative Disorders; Alzheimer’s Disease; Vascular Dementia; Brain Injuries; Tauopathies; Parkinson’s Disease; Lewy Body Dementia; Frontotemporal Dementia; TDP-43 ProteinopathiesLast Updated:August 4, 2016Completed
51
AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation – Pilot Study
Condition(s):Atrial Fibrillation; Heart FailureLast Updated:February 25, 2013Terminated
52
Pharmacokinetics (PK) and Tolerability of AVP-786 in Healthy Volunteers
Condition(s):HealthyLast Updated:June 24, 2014Completed
53
Ablation in Brugada Syndrome for the Prevention of VF
Condition(s):Brugada SyndromeLast Updated:November 1, 2018Recruiting
54
Safety and Pharmacokinetics Study of DU-176b Administered to Non-valvular Atrial Fibrillation With Severe Renal Impairment
Condition(s):Non-valvular Atrial FibrillationLast Updated:February 8, 2019Completed
55
Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot
Condition(s):Healthy VolunteersLast Updated:September 15, 2014Completed
56
Induction of Drug Metabolism: In Vivo Comparison of Carbamazepine and Oxcarbazepine.
Condition(s):Metabolic Clearance RateLast Updated:April 21, 2015Completed
57
Ablation vs Drug Therapy for Atrial Fibrillation – Pilot Trial
Condition(s):Atrial Fibrillation; ArrhythmiaLast Updated:December 3, 2012Completed