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Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease
Condition(s):Polycystic Kidney DiseaseLast Updated:November 30, 2016Completed
SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Niacinamide as an Intervention: 523 Clinical Trials, Page 1 of 6
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Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus
Condition(s):Cutaneous Lupus Erythematosus; Systemic Lupus Erythematosus RashLast Updated:September 22, 2017Unknown status
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Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2)
Condition(s):Polycystic Kidney DiseaseLast Updated:February 8, 2019Completed
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Niacin Supplementation in Healthy Controls and Mitochondrial Myopathy Patients
Condition(s):Mitochondrial MyopathiesLast Updated:May 31, 2019Completed
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Study of Nicotinamide in Early Onset Preeclampsia
Condition(s):PreeclampsiaLast Updated:February 15, 2019Recruiting
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Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients
Condition(s):Non Alcoholic Fatty Liver DiseaseLast Updated:February 20, 2019Recruiting
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Short-term Effect of Extended-release Niacin on Endothelial Function.
Condition(s):HypoalphalipoproteinemiaLast Updated:September 10, 2013Completed
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Nicotinamide as an Early Alzheimer’s Disease Treatment
Condition(s):Alzheimer’s Disease; Mild Cognitive ImpairmentLast Updated:September 24, 2019Recruiting
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Phase I Study of Nicotinamide for Early Onset Preeclampsia
Condition(s):Pregnancy Induced Hypertension; Superimposed Preeclampsia; HypertensionLast Updated:March 15, 2018Completed
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Nicotinamide Riboside and Mitochondrial Biogenesis
Condition(s):Mitochondrial Diseases; Mitochondrial Myopathies; Progressive External Ophthalmoplegia; Progressive Ophthalmoplegia; Progressive; Ophthalmoplegia, External; Mitochondria DNA Deletion; MELAS; Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes; Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)Last Updated:July 4, 2019Recruiting
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Skin Cancer Prevention With Nicotinamide in Transplant Recipients – Pilot Trial
Condition(s):Non-melanoma Skin Cancer; Carcinoma, Squamous Cell; Carcinoma, Basal CellLast Updated:June 20, 2019Recruiting
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Niacin on Immune Activation : a Proof-of-concept Study
Condition(s):HIVLast Updated:April 19, 2018Completed
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GPR109A and Parkinson’s Disease: Role of Niacin in Outcome Measures
Condition(s):Parkinson’s DiseaseLast Updated:July 15, 2019Recruiting
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Niacin for Parkinsons Disease
Condition(s):Parkinson’s DiseaseLast Updated:May 10, 2019Not yet recruiting
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Nicotinic Acid in Hemodialysis Patients With Hyperphosphatemia
Condition(s):HyperphosphatemiaLast Updated:August 29, 2016Unknown status
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Effects of Vitamin B3 in Patients With Ataxia Telangiectasia
Condition(s):Ataxia Telangiectasia; ATM Gene MutationLast Updated:May 22, 2019Enrolling by invitation
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A Pilot Clinical Trial of Pyruvate, Creatine, and Niacinamide in Progressive Supranuclear Palsy.
Condition(s):Progressive Supranuclear PalsyLast Updated:April 6, 2017Completed
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Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions
Condition(s):Central Retinal Vein Occlusion; Branch Retinal Vein OcclusionLast Updated:August 27, 2018Completed
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Nicotinamide Riboside in Systolic Heart Failure
Condition(s):Heart Failure, SystolicLast Updated:July 30, 2019Completed
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The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients
Condition(s):HyperphosphatemiaLast Updated:July 26, 2007Completed
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Effects of Nicotinamide Riboside on Metabolism and Vascular Function
Condition(s):Aging; LipemiaLast Updated:April 10, 2018Recruiting
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DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide.
Condition(s):MelasmaLast Updated:January 6, 2018Completed
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Nicotinamide Riboside Supplementation for Treating Arterial Stiffness and Elevated Systolic Blood Pressure in Patients With Moderate to Severe CKD
Condition(s):Vascular Diseases; Kidney Disease; Blood Pressure; Oxidative StressLast Updated:August 22, 2019Not yet recruiting
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“Pharmacokinetic Study of Nicotinamide Riboside”
Condition(s):Metabolic DisturbanceLast Updated:February 6, 2018Completed
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Nicotinamide Riboside in LVAD Recipients
Condition(s):Heart Failureļ¼Congestive; Heart Failure New York Heart Association Class IV; Mitochondrial AlterationLast Updated:July 30, 2019Completed
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Clinical Trial of 4% Niacinamide Versus 0.05% Desonide for the Treatment of Axillar Hyperpigmentation
Condition(s):HyperpigmentationLast Updated:November 27, 2012Completed
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A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease
Condition(s):Sickle Cell DiseaseLast Updated:September 25, 2019Not yet recruiting
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Role of Prostaglandins on Niacin-Induced Flushing
Condition(s):FlushingLast Updated:March 9, 2010Completed
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Effect of Niacin on Transport of HDL and Relationship to Atherogenic Lipoproteins and Lipolysis
Condition(s):DyslipidemiasLast Updated:June 24, 2016Completed
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Effect of Niacin in the Lipoprotein (a) Concentration
Condition(s):HypercholesterolemiaLast Updated:January 8, 2013Completed
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Effect of Nicotinamide in Friedreich’s Ataxia
Condition(s):Neurodegenerative DisordersLast Updated:June 30, 2017Unknown status
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The Effects of Nicotinamide Riboside Supplementation on NAD+/NADH Ratio and Bioenergetics
Condition(s):HealthyLast Updated:December 14, 2018Recruiting
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Anticancer Activity of Nicotinamide on Lung Cancer
Condition(s):Non-Small-Cell Lung CarcinomaLast Updated:November 25, 2018Active, not recruiting
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The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients
Condition(s):HyperphosphatemiaLast Updated:January 14, 2009Completed
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Effects of Niacin on Intramyocellular Fatty Acid Trafficking in Upper Body Obesity and Type 2 Diabetes Mellitus
Condition(s):Type 2 Diabetes Mellitus; ObesityLast Updated:March 7, 2019Recruiting
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Niacin/Laropiprant and Endothelial Function
Condition(s):Coronary Heart DiseaseLast Updated:October 5, 2011Completed
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The Genetics of Evoked Responses to Niacin and Endotoxemia: The GENE Study
Condition(s):Healthy VolunteersLast Updated:February 23, 2016Completed
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Evaluation of Nicotinamide Riboside in Prevention of Small Fiber Axon Degeneration and Promotion of Nerve Regeneration
Condition(s):Small Fiber NeuropathyLast Updated:August 12, 2019Not yet recruiting
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Assessment Of Vascular Health After Niacin Therapy (AVANT)
Condition(s):Coronary Artery Disease; Carotid Artery Disease; Peripheral Artery DiseaseLast Updated:June 24, 2014Completed
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Effects of Niacin Therapy on Lipoprotein Composition and Function
Condition(s):Cardiovascular DiseaseLast Updated:September 7, 2019Completed
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Safety Study of Nicotinamide to Treat Alzheimer’s Disease
Condition(s):Alzheimer’s DiseaseLast Updated:January 23, 2017Completed
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Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Condition(s):Hypertension; AgingLast Updated:April 19, 2019Recruiting
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ER Niacin/Laropiprant Impact on Cardiovascular Markers and Atheroprogression in HIV-infected Individuals on cART
Condition(s):HIV; AtherosclerosisLast Updated:October 7, 2019Terminated
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SLIM: Combined Effects of Slo-Niacin and Atorvastatin on Lipoproteins and Inflammatory Markers in Hyperlipidemia
Condition(s):DyslipidemiaLast Updated:August 20, 2008Completed
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A Randomized Controlled Trial of Nicotinamide Supplementation in Early Parkinson’s Disease
Condition(s):Parkinson DiseaseLast Updated:December 7, 2018Not yet recruiting
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Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging
Condition(s):Healthy Elderly VolunteersLast Updated:August 13, 2019Recruiting
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Characterization of High Density Lipoprotein (HDL) in Type 2 Diabetes (T2D) After Fenofibrate or Niacin Treatment
Condition(s):Type 2 Diabetes Mellitus; DyslipidemiaLast Updated:June 2, 2014Completed
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Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients
Condition(s):Chronic Renal Failure; HemodialysisLast Updated:May 13, 2016Terminated
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Niacin and Endothelial Function in Early CKD
Condition(s):Chronic Kidney DiseaseLast Updated:April 3, 2014Completed
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Extended Niacin/Laropiprant in Patients With Type 2 Diabetes (0524A-069)
Condition(s):Diabetes Mellitus Type 2Last Updated:October 9, 2015Completed
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Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies
Condition(s):Hodgkin’s Disease; Non-Hodgkin’s LymphomaLast Updated:May 13, 2019Completed
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Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia
Condition(s):Friedreich AtaxiaLast Updated:September 25, 2019Not yet recruiting
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To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions
Condition(s):Retinal Vein OcclusionLast Updated:December 18, 2018Completed
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Effects of Niacin On Fatty Acid Trapping
Condition(s):DyslipidemiaLast Updated:June 24, 2019Active, not recruiting
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Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury
Condition(s):Acute Kidney InjuryLast Updated:March 7, 2018Completed
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Safety & Efficacy of Nicotinamide Riboside Supplementation for Improving Physiological Function in Middle-Aged and Older Adults
Condition(s):AgingLast Updated:November 29, 2016Completed
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Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype
Condition(s):AgingLast Updated:June 5, 2017Unknown status
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Nicotinamide Riboside and Metabolic Health
Condition(s):Obesity; Insulin ResistanceLast Updated:March 20, 2019Completed
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Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis
Condition(s):Aortocoronary Saphenous Vein Bypass Graft Atherosclerosis; Intermediate Saphenous Vein Graft LesionsLast Updated:August 14, 2017Completed
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Skin Maturation in Premature Infants
Condition(s):Premature Birth of NewbornLast Updated:May 15, 2018Terminated
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Effect of Niacin/Laropiprant on Postprandial Lipoprotein Metabolism in Patients With Dyslipoproteinemia
Condition(s):Hyperlipoproteinemia; Metabolic SyndromeLast Updated:March 12, 2014Terminated
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Effects of Niacin on Good Cholesterol in People With Peripheral Arterial Disease
Condition(s):Peripheral Arterial DiseaseLast Updated:February 25, 2013Terminated
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Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid
Condition(s):Dialysis; Cardiovascular Disease; Atherosclerosis; InflammationLast Updated:May 26, 2017Terminated
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The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker
Condition(s):HypercholesterolemiaLast Updated:February 25, 2010Unknown status
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Study of Niacin on Endothelial Function in HIV-infected Subjects With Low High Density Lipoprotein Cholesterol Levels
Condition(s):HIV Infections; Dyslipidemia; Endothelial DysfunctionLast Updated:November 19, 2012Completed
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Nicotinamide in the Treatment of Psoriasis
Condition(s):PsoriasisLast Updated:January 5, 2013Completed
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Efficacy and Safety of Extended Release (ER) Niacin/Laropiprant When Added to Ongoing Lipid-Modifying Therapy in Patients With High Cholesterol or Abnormal Lipid Levels (MK-0524A-133)
Condition(s):Primary Hypercholesterolemia; Mixed DyslipidemiaLast Updated:July 19, 2018Terminated
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Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects
Condition(s):ObesityLast Updated:October 22, 2012Completed
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A Study of 99mTc-3PRGD2 Injection in Healthy Volunteers
Condition(s):HealthyLast Updated:August 7, 2019Completed
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Niacin Skin Flush Response in Patients With Schizophrenia
Condition(s):SchizophreniaLast Updated:May 30, 2015Completed
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A Study of Psilocybin for Major Depressive Disorder (MDD)
Condition(s):Depressive Disorder, MajorLast Updated:May 22, 2019Not yet recruiting
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Nicotinamide in Hemodialysis Patients With Hyperphosphatemia
Condition(s):Chronic Kidney Disease; Hemodialysis; HyperphosphatemiaLast Updated:January 16, 2012Completed
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Nutritional Supplements and Performance During Visual Field Testing (B3 Vitamin)
Condition(s):Visual Field Defect, Peripheral; Glaucoma, Open-AngleLast Updated:May 6, 2019Recruiting
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The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE
Condition(s):Chronic Kidney DiseaseLast Updated:April 17, 2019Active, not recruiting
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A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158)
Condition(s):Hypercholesterolemia, Familial; Heterozygous Familial HypercholesterolemiaLast Updated:November 2, 2015Terminated
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Effects of Psyllium on Niacin Tolerability
Condition(s):Flushing; Hyperlipidemias; DyslipidemiasLast Updated:December 7, 2017Completed
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The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)
Condition(s):Metabolic SyndromeLast Updated:May 5, 2008Completed
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A Study by ChromaDex to Assess the Effects of TRU NIAGEN on Cognitive Function, Mood and Sleep in Older Adults
Condition(s):Cognitive Function; Mood; SleepLast Updated:July 23, 2019Completed
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Lipid Efficacy of the Extended Release Niacin/Laropiprant Combination in Patients With Cardiovascular Disease
Condition(s):Coronary Artery Disease; DyslipidemiasLast Updated:August 17, 2015Terminated
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Extended Release (ER) Niacin/Laropiprant Add on Study (0524A-082)
Condition(s):DyslipidemiaLast Updated:April 8, 2015Withdrawn
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Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.
Condition(s):Obsessive-Compulsive DisorderLast Updated:August 16, 2019Recruiting
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Nicotinic Acid – Pharmacokinetics, Pharmacodynamics, Receptor Expression
Condition(s):HealthyLast Updated:March 14, 2006Unknown status
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Plaque Inflammation and Dysfunctional HDL in AIM-HIGH
Condition(s):Cardiovascular Diseases; Heart Diseases; Coronary Disease; Atherosclerosis; Myocardial InfarctionLast Updated:May 8, 2018Completed
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The Efficacy of Niacin on Hyperphosphatemia in Patients Undergoing Haemodialysis
Condition(s):HyperphosphatemiaLast Updated:May 22, 2017Not yet recruiting
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Evaluation of the Effect of NICOtinic Acid (Niacin) on Elevated Lipoprotein(a) Levels (NICOLa Study)
Condition(s):Elevated Lipoprotein(a) LevelsLast Updated:August 3, 2009Unknown status
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Effect of Nicotinamide Riboside and Pterostilbene Supplementation on Muscle Regeneration in Elderly Humans
Condition(s):Muscle InjuryLast Updated:March 25, 2019Recruiting
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Effect of Nicotinic Acid on Cardiovascular Risks Indices in Polycystic Ovary Syndrome
Condition(s):Polycystic Ovary SyndromeLast Updated:July 11, 2019Completed
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Healthy Combine Study
Condition(s):HealthyLast Updated:December 20, 2017Completed
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Niacin (+) Laropiprant (TREDAPTIVE) Re-examination Study (MK-0524A-119)
Condition(s):Hypercholesterolemia; Mixed DyslipidemiaLast Updated:April 1, 2015Terminated
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NR in Chemo-induced Peripheral Neuropathy
Condition(s):Chemotherapy-induced Peripheral Neuropathy; Breast Cancer Metastatic; Platinum-resistant Recurrent Ovarian CancerLast Updated:August 27, 2019Recruiting
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The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.
Condition(s):Post Traumatic Stress DisorderLast Updated:March 22, 2019Recruiting
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Study to Investigate the Pharmacodynamics, Pharmacokinetics and Safety of a Single Oral Repeated Dose of 500 mg Nicotinic Acid as Tablets in Healthy Subjects
Condition(s):Healthy SubjectsLast Updated:December 10, 2010Completed
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Nicotinic Acid Composition of HDL and Arterial Endothelium Function in Premature Coronary Heart Disease and High HDL
Condition(s):DyslipidemiasLast Updated:January 28, 2013Terminated
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Nicotinamide Riboside With and Without Resveratrol to Improve Functioning in Peripheral Artery Disease
Condition(s):Peripheral Artery DiseaseLast Updated:November 13, 2018Recruiting
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Study to Evaluate the Effect of Nicotinamide Riboside on Immunity
Condition(s):Atherosclerosis; Diabetes; Coronary Artery DiseaseLast Updated:August 26, 2019Completed
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A Study To See If GSK256073A Can Block Niacin-Induced Flushing In Healthy Volunteers
Condition(s):Healthy Subjects; DyslipidaemiasLast Updated:April 26, 2012Completed
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Nicotinamide Riboside in Hospitalized Patients
Condition(s):Inflammation; Acute IllnessLast Updated:October 2, 2019Recruiting
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Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054)
Condition(s):Hypercholesterolemia; HyperlipidemiaLast Updated:February 15, 2017Completed
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Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients
Condition(s):HIV Infections; Hypercholesterolemia; Hypertriglyceridemia; Diabetes MellitusLast Updated:February 28, 2011Completed
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Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease
Condition(s):Chronic Kidney Disease; Sarcopenia; FrailtyLast Updated:December 5, 2018Recruiting