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Treatment of Rheumatoid Arthritis With Methotrexate: Predictors of Response
Condition(s):Rheumatoid ArthritisLast Updated:April 25, 2019Recruiting
SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Methotrexate as an Intervention: 1771 Clinical Trials, Page 1 of 18
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BE Study in Patients – Methotrexate Tablets
Condition(s):Psoriasis; Rheumatoid ArthritisLast Updated:October 19, 2016Unknown status
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Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers
Condition(s):MalariaLast Updated:April 23, 2012Completed
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Methotrexate in the Treatment of Distal Interphalangeal Joint Extensor Tendon Enthesopathy in Nail Psoriasis
Condition(s):Nail PsoriasisLast Updated:November 25, 2018Completed
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The Efficiency Of The Methotrexate At Patients Affected By Grave Pelade
Condition(s):ALOPECIA AREATALast Updated:May 25, 2018Completed
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Individualized High Dose Methotrexate to Treat Cancer in Children Who Have a Significant Risk for Side Effects to Methotrexate
Condition(s):CancerLast Updated:November 15, 2017Active, not recruiting
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Salvage Therapy With High/Low Methotrexate for Loss of Response to Infliximab Dose Escalation
Condition(s):Crohn’s DiseaseLast Updated:October 16, 2018Completed
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High-dose Intravenous Methotrexate Versus Intrathecal Methotrexate for Central Nervous System Prophylaxis in DLBCL
Condition(s):DLBCLLast Updated:April 21, 2017Not yet recruiting
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Pharmacogenomics Study on Treatment of Psoriasis Vulgaris by Methotrexate
Condition(s):Psoriasis VulgarisLast Updated:March 21, 2016Unknown status
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Comparison of Oral Versus Subcutaneous Route of Methotrexate Administration in Moderate to Severe Psoriasis
Condition(s):Psoriasis VulgarisLast Updated:March 12, 2018Not yet recruiting
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Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies
Condition(s):Diabetic Macular EdemaLast Updated:December 26, 2017Terminated
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Methotrexate for Central Serous Chorioretinopathy Treatment Trial
Condition(s):Central Serous ChorioretinopathyLast Updated:July 18, 2012Unknown status
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Comparison of Compliance and Evolution of Functional Capacity of Patients With Rheumatoid Arthritis Treated by Methotrexate Either by Auto-injector or by Conventional Sub-cutaneous Syringe
Condition(s):Arthritis, RheumatoidLast Updated:October 5, 2017Completed
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Methotrexate (Rheumatrex) High Dose Special Investigation (Regulatory Post Marketing Commitment Plan)
Condition(s):Arthritis; Rheumatoid; High DoseLast Updated:November 8, 2017Completed
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Low Dose Oral Methotrexate in Pediatric Crohn’s Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy
Condition(s):Pediatric Crohn’s DiseaseLast Updated:September 12, 2019Recruiting
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Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study
Condition(s):To Evaluate the Effect of Therapy With IT MTX on the Disease Course of Patients With Progressive MSLast Updated:December 28, 2015Unknown status
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Safety and Efficacy of Tofacitinib vs Methotrexate in the Treatment of Psoriatic Arthritis
Condition(s):Psoriatic ArthritisLast Updated:November 7, 2018Recruiting
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The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial)
Condition(s):Myocardial InfarctionLast Updated:April 5, 2013Unknown status
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RCT of Methotrexate Added to Treatment As Usual in Schizophrenia
Condition(s):Schizophrenia; Schizoaffective Disorder; Schizophreniform DisorderLast Updated:September 19, 2015Completed
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Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis
Condition(s):Knee Osteoarthritis; Effusion Synovial; Knee PainLast Updated:March 11, 2019Not yet recruiting
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Two-Dose Methotrexate for Ectopic Pregnancy
Condition(s):Ectopic PregnancyLast Updated:August 8, 2011Completed
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Methotrexate Treatment for Ectopic Pregnancy
Condition(s):Ectopic PregnancyLast Updated:January 21, 2016Completed
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Studying the Effect of Methotrexate Alone Versus Methotrexate and Vitamin D on the Cardiovascular Risk of Psoriatic Patients
Condition(s):PsoriasisLast Updated:April 4, 2019Not yet recruiting
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Study of Two Different Starting Doses of Methotrexate When Starting Treatment in Rheumatoid Arthritis
Condition(s):Rheumatoid ArthritisLast Updated:September 5, 2014Completed
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Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia
Condition(s):Acute Lymphoblastic LeukemiaLast Updated:February 23, 2015Completed
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Effect of Methotrexate on Inflammatory Response in Adult Atopic Dermatitis Patients
Condition(s):Atopic DermatitisLast Updated:February 6, 2018Active, not recruiting
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Discovery Stage IND EXEMPT Clinical Study – Etoposide Plus Methotrexate and Single Nucleotide Polymorphisms
Condition(s):Small Cell Lung CancerLast Updated:March 28, 2019Active, not recruiting
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The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy
Condition(s):Ectopic Pregnancy; InfertilityLast Updated:March 16, 2016Completed
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A Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy
Condition(s):Arthritis, JuvenileLast Updated:July 8, 2019Active, not recruiting
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Low Dose Cyclosporin and Methotrexate Therapy in Diabetes
Condition(s):Type 1 Diabetes MellitusLast Updated:April 12, 2011Completed
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Methotrexate in Symptomatic Knee Osteoarthritis
Condition(s):OsteoarthritisLast Updated:July 28, 2012Completed
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Concomitant Longitudinal Evaluation of Adalimumab With Methotrexate in the Real World: the CLEAR Study
Condition(s):PsoriasisLast Updated:February 16, 2018Completed
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Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors
Condition(s):Recurrent Childhood Medulloblastoma; Recurrent Childhood Ependymoma; Childhood Atypical Teratoid/Rhabdoid Tumor; Embryonal Tumor With Abundant Neuropil and True Rosettes; Metastatic Malignant Neoplasm to the LeptomeningesLast Updated:March 15, 2019Recruiting
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Trial in Patients With Psoriasis Treated With Methotrexate Using an Optimized Treatment Schedule (METOP)
Condition(s):Psoriasis VulgarisLast Updated:September 15, 2016Completed
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Ultrasound as Imaging Biomarker of Early Response to Tocilizumab and Methotrexate in Very Early Rheumatoid Arthritis
Condition(s):Rheumatoid ArthritisLast Updated:July 28, 2016Recruiting
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Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal Methotrexate
Condition(s):Non-infectious Intermediate and Posterior UveitisLast Updated:March 12, 2019Terminated
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Discovery Stage IND EXEMPT Clinical Study – Etoposide OS Plus Methotrexate OS and Single Nucleotide Polymorphisms
Condition(s):Small Cell Lung CancerLast Updated:March 28, 2019Active, not recruiting
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Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma
Condition(s):Cancer; Leukemia; LymphomaLast Updated:July 12, 2019Completed
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A Study of the Use of Methotrexate in the Treatment of Chronic Idiopathic Urticaria
Condition(s):UrticariaLast Updated:February 18, 2016Terminated
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METhotrexate Therapy Effects in the Physical Capacity of Patients With ISchemic Heart Failure (METIS Trial)
Condition(s):Heart Failure; Myocardial IschemiaLast Updated:March 29, 2013Completed
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Dose Ranging Study to Compare the Efficacy and Safety of Methotrexate in Plaque Type Psoriasis
Condition(s):PsoriasisLast Updated:August 24, 2010Completed
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Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children With Recurrent Posterior Fossa Brain Tumors
Condition(s):Brain Tumor RecurrentLast Updated:June 21, 2019Recruiting
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Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer
Condition(s):Recurrent or Metastatic Head and Neck CarcinomaLast Updated:February 13, 2019Completed
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Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone
Condition(s):Rheumatoid ArthritisLast Updated:January 12, 2018Completed
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Clinical Trial Evaluating Methotrexate + Biologic Versus Methotrexate, Salazopyrine and Hydroxychloroquine in Patients With Rheumatoid Arthritis and Insufficient Response to Methotrexate
Condition(s):Rheumatoid Arthritis; Insufficient Response to Methotrexate.Last Updated:March 15, 2016Not yet recruiting
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Treatment With High Dose Methotrexate in Patients With Eosinophilic Fasciitis
Condition(s):FasciitisLast Updated:August 10, 2011Completed
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Exposure Study Comparing 3 Routes of Methotrexate (MTX) Administration
Condition(s):Rheumatoid ArthritisLast Updated:January 8, 2014Completed
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A Safety and Efficacy Study of Ustekinumab in Patients With Plaque Psoriasis Who Have Had an Inadequate Response to Methotrexate
Condition(s):PsoriasisLast Updated:November 13, 2014Completed
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Add-on Methotrexate for the Treatment of Schizophrenia
Condition(s):SchizophreniaLast Updated:December 10, 2017Not yet recruiting
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Comparison of Methotrexate Versus Interferon-alfa 2b in Patients With Primary Cutaneous T-cell Lymphomas
Condition(s):Lymphoma, T-Cell, Cutaneous; Mycosis FungoidesLast Updated:July 12, 2017Unknown status
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Low-dose Methotrexate for Change in Global Initiative for Asthma Step 5 Medications in Chronic Severe Asthma
Condition(s):Low Dose Methotrexate in Severe Chronic AsthmaLast Updated:April 22, 2019Not yet recruiting
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Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422)
Condition(s):Arthritis, PsoriaticLast Updated:March 13, 2017Completed
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Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI
Condition(s):Myocardial Infarction, Anterior Wall; Myocardial Remodeling, VentricularLast Updated:April 23, 2018Recruiting
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Methotrexate in the Treatment of Chronic Idiopathic Urticaria
Condition(s):Chronic UrticariaLast Updated:September 19, 2017Completed
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GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA (GOLMEPsA)
Condition(s):Psoriatic ArthritisLast Updated:September 27, 2019Recruiting
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Comparison Study of Psoriasis Severity Assessment Tools
Condition(s):PsoriasisLast Updated:April 14, 2016Completed
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Rheumatoid Arthritis Response to Methotrexate
Condition(s):Rheumatoid ArthritisLast Updated:August 5, 2019Recruiting
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Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (Methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia
Condition(s):Large Granular Lymphocytes LeukemiaLast Updated:August 28, 2018Recruiting
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Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis
Condition(s):Langerhans Cell HistiocytosisLast Updated:September 10, 2018Completed
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Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo
Condition(s):PolyarthritisLast Updated:December 8, 2011Unknown status
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A Bioavailability Study of Methotrexate 25 mg Administered by Needle Injection and a Pre Filled Needle-free Device in Healthy Volunteers.
Condition(s):HealthyLast Updated:March 31, 2017Completed
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A Study to Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA)
Condition(s):Rheumatoid ArthritisLast Updated:January 31, 2014Completed
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Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
Condition(s):Osteosarcoma; Leukemia; LymphomaLast Updated:June 4, 2014Completed
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Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis
Condition(s):Sarcoid-associated Uveitis; Ocular Sarcoidosis; Macular EdemaLast Updated:May 30, 2014Terminated
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CNS Prophylaxis in Diffuse Large B-cell Lymphoma
Condition(s):Diffuse Large B-cell LymphomaLast Updated:June 3, 2016Recruiting
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Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis
Condition(s):Rheumatoid ArthritisLast Updated:March 20, 2019Completed
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Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe Psoriasis
Condition(s):PsoriasisLast Updated:July 7, 2016Recruiting
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A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate
Condition(s):Pharmacokinetics of Isavuconazole; Pharmacokinetics of Methotrexate; Pharmacokinetics of 7-hydroxymethotrexate; Healthy SubjectsLast Updated:June 20, 2013Completed
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Human Factors Study of Methotrexate Prefilled Pen (50 mg/mL) in Patients With Juvenile Idiopathic Arthritis
Condition(s):Juvenile Idiopathic ArthritisLast Updated:March 26, 2018Completed
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COMMIT (Combination Of Maintenance Methotrexate-Infliximab Trial)
Condition(s):Crohn’s DiseaseLast Updated:December 10, 2013Completed
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A Study Comparing the Safety and Efficacy of Risankizumab to Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis
Condition(s):PsoriasisLast Updated:August 15, 2019Active, not recruiting
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To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids
Condition(s):Allogeneic Disease; GVH – Graft Versus Host Reaction; GVHD, Acute; Stem Cell Transplant ComplicationsLast Updated:July 15, 2019Recruiting
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The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis
Condition(s):PsoriasisLast Updated:July 10, 2013Completed
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Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients
Condition(s):Rheumatoid ArthritisLast Updated:February 22, 2019Recruiting
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Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer
Condition(s):KRAS Gene Mutation; Metastatic Malignant Neoplasm in the Brain; Recurrent Non-Small Cell Lung Carcinoma; Stage IV Non-Small Cell Lung Cancer AJCC v7Last Updated:April 17, 2019Suspended
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Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study
Condition(s):Brain Tumor; Malignant Neoplasm of Fourth Ventricle of BrainLast Updated:January 17, 2018Completed
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Efficacy of Starting Methotrexate Early in Chikungunya Arthritis
Condition(s):Early Chikungunya ArthritisLast Updated:October 29, 2018Completed
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The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2)(COMPLETED)
Condition(s):PsoriasisLast Updated:April 4, 2017Completed
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VACcination In Methotrexate Treated Rheumatoid Arthritis Patients
Condition(s):Rheumatoid ArthritisLast Updated:January 31, 2019Active, not recruiting
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Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study.
Condition(s):Severe Plaque Type PsoriasisLast Updated:September 22, 2014Unknown status
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Mechanism of Action Study for Psoriasis
Condition(s):PsoriasisLast Updated:August 1, 2017Completed
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A Study to Evaluate the Pharmacokinetics of ASP1707 and Methotrexate in Patients With Rheumatoid Arthritis
Condition(s):Rheumatoid ArthritisLast Updated:March 13, 2019Completed
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Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS)
Condition(s):Ankylosing SpondylitisLast Updated:September 28, 2015Completed
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Intravitreal Methotrexate and R2(Rituximab & Lenalidomide) Regimen in Newly-diagnosed Primary Vitreoretinal Lymphoma
Condition(s):Primary Intraocular LymphomaLast Updated:November 15, 2018Not yet recruiting
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Methotrexate as a Steroid-sparing Agent in Idiopathic Retroperitoneal Fibrosis: a Randomised, Multicenter Trial
Condition(s):Idiopathic Retroperitoneal Fibrosis; Perianeurysmal Retroperitoneal Fibrosis; Chronic PeriaortitisLast Updated:November 12, 2010Unknown status
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A Study of the Combination of Cetuximab and Methotrexate in Recurrent or Metastatic Cancer of the Head and Neck
Condition(s):Squamous Cell Carcinoma of the Head and NeckLast Updated:May 3, 2019Active, not recruiting
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CAMEO: Canadian Methotrexate and Etanercept Outcome Study
Condition(s):Rheumatoid ArthritisLast Updated:July 14, 2014Completed
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Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies
Condition(s):Acute Lymphoblastic Leukemia; Acute Myelocytic Leukemia; Chronic Myelocytic Leukemia; Hodgkin’s Disease; Myelodysplastic SyndromeLast Updated:March 14, 2013Completed
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Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM
Condition(s):Polymyositis; DermatomyositisLast Updated:April 6, 2016Completed
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Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R
Condition(s):Breast Cancer; Brain Cancer; Gastrointestinal Cancers; Genitourinary Cancers; Gynecologic Cancers; Head and Neck Cancers; Melanoma; Thoracic CancersLast Updated:August 20, 2019Completed
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Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study
Condition(s):Rheumatoid ArthritisLast Updated:November 26, 2014Terminated
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ACP-196 Versus Placebo in Subjects With Rheumatoid Arthritis on Background Methotrexate
Condition(s):Rheumatoid ArthritisLast Updated:March 25, 2019Completed
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A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid Arthritis
Condition(s):Rheumatoid ArthritisLast Updated:September 13, 2016Completed
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Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma
Condition(s):OsteosarcomaLast Updated:April 26, 2017Completed
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Optimizing Psoriasis Treatment of Etanercept Combined Methotrexate
Condition(s):PsoriasisLast Updated:August 16, 2018Completed
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Kunxian for the Treatment of Rheumatoid Arthritis
Condition(s):Rheumatoid ArthritisLast Updated:March 8, 2017Unknown status
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Co-Administration Of Methotrexate And CP-690,550
Condition(s):Rheumatoid ArthritisLast Updated:January 29, 2013Completed
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Methotrexate in Metastatic Colorectal Cancer With MSH2 Deficiency
Condition(s):Advanced Colorectal CancerLast Updated:October 13, 2016Terminated
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Initial Treatment With Golimumab in Early PsA
Condition(s):Psoriatic ArthritisLast Updated:November 22, 2018Completed
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Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid Arthritis
Condition(s):Juvenile Rheumatoid ArthritisLast Updated:June 12, 2019Terminated