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Benefits of Glycopyrrolate on Intubation With Rigid-videostylet (OptiScope®)
Condition(s):Cholecystitis, AcuteLast Updated:May 22, 2018Completed
Glycopyrrolate as an Intervention: 181 Clinical Trials, Page 1 of 2
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2
Excessive Sweating Caused by Antidepressants: Measurement and Treatment With Glycopyrrolate (AIDES-G)
Condition(s):Hyperhydrosis; DepressionLast Updated:August 24, 2016Terminated
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Effect of Glycopyrrolate and Atropine on Catheter-Related Bladder Discomfort
Condition(s):Catheter Site Discomfort; Complications; Anesthesia; Urinary Bladder NeoplasmsLast Updated:October 27, 2014Unknown status
4
Minimizing Nausea and Vomiting During Spinals for CS
Condition(s):Nausea; VomitingLast Updated:July 16, 2018Recruiting
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Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Adult Patients Undergoing Lower Extremity Surgery Under Spinal Anesthesia
Condition(s):Spinal AnesthesiaLast Updated:March 12, 2019Terminated
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Effect of Atropine or Glycopyrrolate on the Prevention of Bradycardia During Sedation Using Dexmedetomidine in Geriatric Patients Undergoing Total Knee Replacement Under Spinal Anesthesia
Condition(s):Spinal AnesthesiaLast Updated:September 20, 2018Completed
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Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
Condition(s):Lower Extremity FractureLast Updated:August 15, 2018Recruiting
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Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation
Condition(s):SialorrheaLast Updated:March 20, 2014Completed
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Pharmacokinetics of Neostigmine and Glycopyrrolate
Condition(s):Pharmacokinetic Behavior of Neostigmine and Glycopyrrolate After Administration Via Different RoutesLast Updated:July 19, 2019Recruiting
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Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson’s Disease
Condition(s):Sialorrhea; Parkinson’s DiseaseLast Updated:April 13, 2018Recruiting
11
The Effect of BEVESPI AEROSPHERE ® Therapy on Exercise Tolerance in COPD
Condition(s):Pulmonary Disease, Chronic ObstructiveLast Updated:January 31, 2019Completed
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Safety and Efficacy Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to Severe) Drooling in Pediatric Patients 3 to 18 Years of Age With Cerebral Palsy or Other Neurologic Conditions
Condition(s):Cerebral Palsy; Neurological Conditions; Mental Retardation; SialorrheaLast Updated:June 5, 2012Completed
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A Dose-Ranging Study of the Effect of Glycopyrrolate in Subjects With Axillary Hyperhidrosis
Condition(s):HyperhidrosisLast Updated:September 11, 2018Completed
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Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPD
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:February 21, 2017Completed
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Comparator Study of the Effect of Glycopyrrolate and Glycopyrronium in Subjects With Axillary Hyperhidrosis
Condition(s):HyperhidrosisLast Updated:August 28, 2018Completed
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Study to Determine the Amount of Glycopyrrolate Absorbed in the Lungs After Taking the Medicine With a eFlow Nebulizer and Seebri® Breezhaler® With and Without Activated Charcoal in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).
Condition(s):COPDLast Updated:September 27, 2018Completed
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Efficacy and Safety of Glycopyrrolate Bromide of COPD Patients
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:March 5, 2019Completed
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Echocardiographic Study of the Haemodynamic Effects of Remifentanil With and Without Glycopyrrolate in Healthy Children
Condition(s):Urological SurgeryLast Updated:January 3, 2012Completed
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RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials Cooperative
Condition(s):COPD (Chronic Obstructive Pulmonary Disease)Last Updated:July 24, 2019Recruiting
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Biopharmaceutical Study of Glyco pMDI With or Without Charcoal Block vs IV Bolus in Healthy Volunteers
Condition(s):HealthyLast Updated:October 26, 2010Completed
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Pharmacokinetic Interaction Study of Glycopyrrolate and Formoterol in Healthy Volunteers
Condition(s):COPDLast Updated:April 2, 2012Completed
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Randomized Cross Over Study to Assess Efficacy and Safety of BDP/FF and Glycopyrrolate
Condition(s):Pulmonary Disease, Chronic ObstructiveLast Updated:March 5, 2019Completed
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Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine
Condition(s):FeverLast Updated:April 29, 2015Completed
24
A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:February 13, 2018Completed
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Sugammadex vs. Neostigmine for Neuromuscular Blockade Reversal in Thoracic Surgical Patients
Condition(s):Neuromuscular BlockadeLast Updated:October 17, 2019Completed
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Prevention of Postoperative Events Following Reversal With Sugammadex or Neostigmine
Condition(s):Pulmonary ComplicationsLast Updated:August 21, 2018Not yet recruiting
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Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant
Condition(s):SurgeryLast Updated:July 19, 2019Recruiting
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“Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy”
Condition(s):Anesthesia RecoveryLast Updated:June 26, 2018Completed
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Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:March 28, 2018Completed
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Efficacy and Safety of QVA149 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:June 28, 2018Completed
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Safety and Tolerability of QVA149 (Indacaterol/Glycopyrrolate) Compared to Placebo and to Indacaterol in Patients With Moderate to Severe Stable Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:November 28, 2012Completed
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Effect of Sugammadex vs. Neostigmine/Glycopyrrolate on Pediatric Emergence Delirium in Sevoflurane-rocuronium Anesthesia
Condition(s):Emergence DeliriumLast Updated:September 4, 2018Recruiting
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Study of Sugammadex Versus Usual Care on Incidence of Residual Blockade at Post Anesthesia Care Unit Admission (P07981)
Condition(s):Surgical Procedures, ElectiveLast Updated:May 8, 2017Completed
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Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular
Condition(s):Neuromuscular Blockade; AnesthesiaLast Updated:January 31, 2019Recruiting
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Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [i.e., Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered Using an eFlow Nebulizer in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:March 7, 2018Completed
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Study to Determine if Administration of Sugammadex Impacts Hospital Efficiency
Condition(s):Neuromuscular BlockadeLast Updated:April 10, 2019Completed
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A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment.
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:July 30, 2015Completed
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A Study to Assess the PK and Safety of PT010 in Subjects With COPD Following Single and Repeat Dose
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:May 9, 2018Completed
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Use of Prokinetics During Inpatient Bowel Care for SCI Patients
Condition(s):Spinal Cord Injury; Neurogenic BowelLast Updated:August 28, 2017Unknown status
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Clozapine-induced Hypersalivation – Feasibility Trial
Condition(s):SialorrheaLast Updated:February 26, 2018Completed
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Street Fitness in Surgical Patients Undergoing General Anesthesia After Reversal of Neuromuscular Blockade
Condition(s):Anesthesia Recovery PeriodLast Updated:October 17, 2011Unknown status
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Efficacy of LAMA Added to ICS in Treatment of Asthma
Condition(s):AsthmaLast Updated:March 28, 2017Completed
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Rates and Severity of PONV for Neuromuscular Block Reversal in Patients Receiving Gastric Bypass Bariatric Surgery
Condition(s):Bariatric Surgery CandidateLast Updated:September 30, 2019Withdrawn
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Transdermal Administration of a Prokinetic Agent for Bowel Evacuation in Persons With SCI
Condition(s):Spinal Cord Injury; Neurogenic BowelLast Updated:March 6, 2017Completed
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Safety and Efficacy Study of Glyco pMDI After Single and Repeated Administration
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:March 28, 2017Completed
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Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery
Condition(s):BurnsLast Updated:August 7, 2019Recruiting
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Efficacy of Peripheral Nerve Stimulator in Assessing Sensory Nerve Block Level of Spinal Anesthesia
Condition(s):Orthopedic Surgery-lower Leg SurgeryLast Updated:March 27, 2019Recruiting
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Intraoperative Video Laryngoscopy as Adjunct for Nerve Monitoring
Condition(s):Vocal Cord Function in Neck ProceduresLast Updated:November 12, 2018Recruiting
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Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Condition(s):Microlaryngoscopy; Rigid BronchoscopyLast Updated:April 26, 2019Recruiting
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Sugammadex and Brain Waves
Condition(s):AnaesthesiaLast Updated:June 10, 2010Completed
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Triple in Asthma Dose Finding
Condition(s):AsthmaLast Updated:March 28, 2017Completed
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The Use of Sugammadex in the Critically Ill
Condition(s):Critical IllnessLast Updated:August 19, 2019Recruiting
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Investigation of Sugammadex in Outpatient Urological Procedures
Condition(s):Malignant Neoplasms of Urinary Tract; Bladder CancerLast Updated:July 25, 2019Active, not recruiting
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Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate in Chronic Obstructive Pulmonary Disease
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:March 5, 2019Completed
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Pharmacokinetics of CHF 5993 pMDI With and Without Spacer in COPD Patients
Condition(s):COPDLast Updated:March 20, 2015Completed
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Intranasal Administration of a Prokinetic for Bowel Evacuation in Persons With SCI
Condition(s):SCILast Updated:July 23, 2013Completed
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Chronotropic Incompetence in Patients With HFpEF
Condition(s):Heart FailureLast Updated:April 4, 2019Completed
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Role of Sugammadex as Reversal Agent in Patients Extubated Immediately After Isolated Coronary Artery Bypass Grafting Surgery
Condition(s):Surgery; Coronary Artery DiseaseLast Updated:May 3, 2019Active, not recruiting
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CURES: The Effect of Deep Curarisation and Reversal With Sugammadex on Surgical Conditions and Perioperative Morbidity
Condition(s):Obesity; Laparoscopic Gastric Bypass Surgery; Surgical Conditions; Respiratory Function; Cerebral Tissue OxygenationLast Updated:April 24, 2017Completed
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Acute Effect of Aclidinium on Hyperinflation and Ventilation Inhomogeneity in Severe COPD Patients
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:October 28, 2014Completed
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Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)
Condition(s):Reversal of Neuromuscular BlockadeLast Updated:September 17, 2019Completed
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A Study to Assess the Long-term Safety of QVA149
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:January 28, 2013Completed
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Effect of a LAMA and a uLABA on the Methacholine Dose-response Curve
Condition(s):AsthmaLast Updated:June 12, 2017Completed
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Effects of Bevespi on Ventilation and Gas Exchange Abnormalities in COPD Assessed by 129Xe MRI
Condition(s):CopdLast Updated:May 17, 2019Recruiting
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Use of High Resolution Colonic Manometry in Studying Motility
Condition(s):Gastrointestinal DysfunctionLast Updated:November 14, 2016Unknown status
66
Pharmacokinetics and Safety Study of PT010 in Healthy Subjects
Condition(s):COPDLast Updated:June 11, 2018Completed
67
Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:February 7, 2017Completed
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Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)
Condition(s):Neuromuscular BlockadeLast Updated:October 17, 2019Recruiting
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Efficacy, Safety, and Pharmacokinetics of Sugammadex for Reversal of Neuromuscular Blockade (NMB) in Pediatric Participants (MK-8616-089)
Condition(s):Neuromuscular BlockadeLast Updated:September 20, 2019Recruiting
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Long Term Safety and Tolerability of QVA149 Versus Tiotropium in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:December 3, 2013Completed
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The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications
Condition(s):Postoperative Complications; Neuromuscular BlockadeLast Updated:April 9, 2019Active, not recruiting
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Residual Neuromuscular Blockade in Cardiac Surgery Patients
Condition(s):Residual Neuromuscular BlockadeLast Updated:June 19, 2018Not yet recruiting
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Comparison of Sugammadex (MK-8616/Org 25969) With Neostigmine Administered at 1-2 Post-tetanic Counts (PTCs) After Administration of Rocuronium or Vecuronium (19.4.302/P05945/MK-8616-025)
Condition(s):Anesthesia, GeneralLast Updated:March 6, 2019Completed
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Efficacy and Safety of Sugammadex Dosed According to Actual Body Weight (ABW) or Ideal Body Weight (IBW) in Reversal of Neuromuscular Blockade (NMB) in Morbidly Obese Participants (MK-8616-146)
Condition(s):Neuromuscular BlockadeLast Updated:April 18, 2019Completed
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Comparison of Sugammadex (Org 25969) With Neostigmine as Reversal Agents for Rocuronium or Vecuronium at Reappearance of T2 (P05960)
Condition(s):Anesthesia, GeneralLast Updated:February 15, 2019Completed
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Comparison of Rocuronium and Org 25969 With Cisatracurium and Neostigmine (19.4.310)(P05931)
Condition(s):Anesthesia, GeneralLast Updated:August 18, 2017Completed
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Randomized, Crossover Safety and Pharmacokinetics Study of PT010
Condition(s):COPDLast Updated:October 27, 2014Completed
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Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Condition(s):Airway Reflexes, Protective; Recovery After Neuromuscular Block; Anesthetic RecoveryLast Updated:May 7, 2014Completed
79
Reversal of Neuromuscular Blockade With Sugammadex or Usual Care in Hip Fracture Surgery or Joint (Hip/Knee) Replacement (P07038)
Condition(s):Neuromuscular Blockade; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Blood Coagulation; Antithrombotic AgentsLast Updated:April 12, 2017Completed
80
Anesthetics in Rhytidoplasty – A Comparison Study
Condition(s):RhytidoplastyLast Updated:April 6, 2015Completed
81
Glycopyrrolate/Formoterol Fumarate MDI Compared With Spiriva® as An Active Control in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:May 23, 2016Completed
82
Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.
Condition(s):Nerve Block; General Anesthesia; Spinal Anesthesia; Pain; Postoperative Nausea and VomitingLast Updated:February 14, 2018Completed
83
Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage
Condition(s):Spinal Cord InjuryLast Updated:July 2, 2014Completed
84
Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy
Condition(s):Sedation, BronchoscopyLast Updated:May 11, 2018Completed
85
QVA Mechanistic Efficacy Study (Receptor Effects, Etc)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:February 22, 2019Completed
86
A Multicenter, 4-week Crossover (Total Duration 12 Weeks) to Determine the Impact of QVA149 on Nocturnal Oxygen Levels in Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:November 10, 2017Completed
87
Randomized, Double-blind, Placebo-controlled, Multicenter, Cross-over Study to Assess the Effects of a 3 Week Therapy Each With QVA149 Versus Placebo on Pulmonary Function and Average Physical Activity Levels in Patients With COPD.
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:March 7, 2016Completed
88
A Dose-Range Finding Study of SUN-101 in Subjects With Moderate to Severe COPD
Condition(s):COPDLast Updated:March 12, 2018Completed
89
NVA237 BID Versus Placebo Twelve-week Efficacy Study
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:March 9, 2015Completed
90
NVA237 Versus Placebo 12-week Efficacy Study
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:February 12, 2015Completed
91
Long Term Safety Study of NVA237 vs QAB149 in COPD Patients
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:February 17, 2016Completed
92
A Multi-centre Randomized Double Blind 52-week Study to Assess the Safety of QVA149 Compared to QAB149 in Patients With COPD Who Have Moderate to Severe Airflow Limitation
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:February 29, 2016Completed
93
Comparing the Pharmacokinetics, Safety and Tolerability of NVA237 in Renal Impairment
Condition(s):Renal ImpairmentLast Updated:June 5, 2012Completed
94
Efficacy, Safety and Tolerability of NVA237 in Patients With Chronic Obstructive Pulmonary Disease
Condition(s):Chronic Obstructive Pulmonary Disease (COPD)Last Updated:July 16, 2014Completed
95
Comparison of Safety and Efficacy of the Combination Product QVA149A Against the Concurrent Administration of the Individual Components, QAB149 and NVA237, in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:January 16, 2014Completed
96
Sugammadex on Remifentanil Ce for Preventing Emergence Cough
Condition(s):Gallbladder DiseasesLast Updated:July 10, 2018Recruiting
97
Effect of NVA237 on Exercise Endurance in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:April 10, 2012Completed
98
Efficacy and Safety of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:March 3, 2015Completed
99
A Study to Investigate the Bronchodilatory Effect of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition(s):Chronic Obstructive Pulmonary DiseaseLast Updated:August 2, 2016Completed
100
Functional Respiratory Imaging After Neostigmine or Sugammadex
Condition(s):Respiratory-Gated Imaging TechniquesLast Updated:April 20, 2015Completed