Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw

Overview

The aim of the study is to assess the correlation between orthodontic treatment and temporomandibular joint (TMJ). For that, an evaluation with a virtual articulator (Modjaw) is carried out before and after the treatment. The condylar course are compared. Furthermore, the eventual TMJ symptoms are also compared before and after.

Full Title of Study: “Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw in Adults”

Study Type

• Study Type: Interventional
• Study Design
  • Allocation: N/A
  • Intervention Model: Single Group Assignment
  • Primary Purpose: Diagnostic
  • Masking: None (Open Label)
• Study Primary Completion Date: April 7, 2026

Interventions

• Device: Review by Modjaw
  • A review by Modjaw’s will be done before the braces treatment and after.

Arms, Groups and Cohorts

• Other: Braces
  • Patients will receive an orthodontic treatment with fixed braces for 12 to 24 months

Clinical Trial Outcome Measures

Primary Measures

• Gap reduction between the interincisive point in mouth opening and the ordinate axis
  • Time Frame: Up to 24 months
  • Define if there is an improvement in the straightness of the condylar path by measuring the gap between the interincisive point in mouth opening and the ordinate axis in mm assessed by Modjaw

Secondary Measures

• Condylar courses homogeneity
  • Time Frame: Up to 24 months
  • Qualitative comparison of the homogeneity of the condylar courses before and after treatment
• Condylar courses symmetry
  • Time Frame: Up to 24 months
  • Qualitative comparison of the symmetry of the condylar symmetry before and after treatment
• Condylar courses straightness
  • Time Frame: Up to 24 months
  • Qualitative comparison of the straightness of the condylar symmetry before and after treatment
• Amplitude of the condylar path
  • Time Frame: Up to 24 months
  • Virtual path length in mm assessed by Modjaw
• Straightness of the condylar path
  • Time Frame: Up to 24 months
  • Y-axis deviation in mm assessed by Modjaw
• Adverses events
  • Time Frame: Up to 24 months
  • Adverse events will be assessed before and after treatment
• Pain assessment
  • Time Frame: Up to 24 months
  • Pain is assessed by an analogic visual scale from 0 (no pain) to 10 (maximum pain)

Participating in This Clinical Trial

Inclusion Criteria

• Major patient (≥18 years) – First dentofacial orthopedic consultation at the dental clinic of Montpellier – Patient requiring multi-attachment orthodontic treatment (vestibular or lingual) for a duration ≤2 years – Signed informed consent Exclusion Criteria:

• Syndromic patient – Orthodontic treatment with aligners – General joint or bone pathology – Patients with oral hygiene incompatible with orthodontic treatment

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

• Lead Sponsor
  • University Hospital, Montpellier
• Provider of Information About this Clinical Study
  • Sponsor
• Overall Contact(s)
  • Clémence HERTEAU, +334 67 33 67 10, c-herteau@chu-montpellier.fr