Low Level Laser Therapy Applied in Orthodontic Tooth Movement
Overview
Currently, orthodontic treatment takes 2-3 years.. If we accelerate tooth movement by low energy laser therapy, we could reduce treatment time. Low Level Laser Therapy(LLLT) applied in Orthodontic Tooth Movement, which stimulates formation of osteoclast-like cells expression in vitro. Osteoclast can be served as an index for tooth movement. Increasing the number of osteoclast will increase bone formation and tooth movement. We plan to find a useful clinical protocol to improve the efficiency of orthodontic tooth movement. Test low energy laser in vitro. Find an effective wavelength and irradiation time to stimulate formation of osteoclast. Develop an useful protocol that clinical orthodontist could follow and reduce orthodontic treatment time.
Study Type
- Study Type: Interventional
- Study Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Primary Purpose: Device Feasibility
- Masking: Triple (Participant, Care Provider, Outcomes Assessor)
- Study Primary Completion Date: August 26, 2022
Interventions
- Device: Low Level Laser Therapy
- Low level laser therapy could provide energy to trigger cell differentiation.
- Other: Placebo
- Placebo
Arms, Groups and Cohorts
- Experimental: with LLLT
- Placebo Comparator: without LLLT
Clinical Trial Outcome Measures
Primary Measures
- Orthodontic tooth movement
- Time Frame: 1-6month
- the distance between canine and premolar
Secondary Measures
- bone density after Orthodontic tooth movement
- Time Frame: 1-6month
- bone density change around canine
Participating in This Clinical Trial
Inclusion Criteria
- Patients with good oral hygiene – 18 years old – Patients who required bilateral canine retraction into the extracted premolar Exclusion Criteria:
- Serious medical history – Poor oral hygiene – Previous orthodontic treatment – Orthognathic surgery or syndromic patients
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: N/A
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- China Medical University Hospital
- Provider of Information About this Clinical Study
- Sponsor
- Overall Official(s)
- SHENG-FEN HUANG, Study Chair, China Medical University Hospital
- Overall Contact(s)
- Jian-hong Yu, doctor, +886 422053366, kenkoyu@mail.cmu.edu.tw
Citations Reporting on Results
Farivar S, Malekshahabi T, Shiari R. Biological effects of low level laser therapy. J Lasers Med Sci. 2014 Spring;5(2):58-62.
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