The Effectiveness of Single Antibiotic Paste Nitrofurantoin Versus Double Antibiotic Paste
Overview
In our study, we used nitrofurantoin as a root canal medication in patients suffering from symptomatic irreversible pulpitis in alleviating pain compared with double antibiotic paste.
Full Title of Study: “The Effectiveness of Single Antibiotic Paste Nitrofurantoin V/S Double Antibiotic Paste in Alleviation of Post-Operative Pain in Adult Patients Symptomatic Irreversible Pulpitis”
Study Type
- Study Type: Interventional
- Study Design
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Primary Purpose: Treatment
- Masking: Single (Participant)
- Study Primary Completion Date: October 24, 2022
Detailed Description
This study aims to compare the efficacy in alleviating pain between intracanal medicaments Nitrofurantoin versus double antibiotic paste.
Interventions
- Drug: Nitrofurantoin
- Nitrofurantoin has been found to successfully eradicate gram-negative bacteria such as Enterococcus faecalis that one of the most important bacteria in endodontic lesions
- Drug: Double Antibiotic
- DAP is a combination of two antibiotics which are ciprofloxacin and metronidazole
Arms, Groups and Cohorts
- Experimental: Nitrofurantoin
- Experimental: Double antibiotic paste
- No Intervention: Control
Clinical Trial Outcome Measures
Primary Measures
- To alleviate dental pain
- Time Frame: 12 hours upto 72 hours following placement of intracanal medicament
- Dental pain will be measured by using Visual Analogue Scale(VAS) which is an 10-point scale from 0-10 where 0 represents no pain and 10 represents the worst pain measured
Participating in This Clinical Trial
Inclusion Criteria
- No medical history – no history of allergy to medications used in root canal treatment – patients suffering from Symptomatic Irreversible Pulpitis Exclusion Criteria:
- Patients who were not suitable for conventional root canal treatment – multirooted teeth
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 50 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- Altamash Institute of Dental Medicine
- Provider of Information About this Clinical Study
- Principal Investigator: Hira Abbasi, Principal Investigator – Altamash Institute of Dental Medicine
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