Urinary Antigen Test for Stretococcus Pneumoniae Serotype Prevalence in Community Acquired Pneumonia

Overview

This is an epidemiology study for the prevalence and serotypes of pneumococcus pneumoniae in hospitalized patients with community acquired pneumonia (CAP). The serotypes of the pneumococcus pneumoniae will be determined by a urinary antigen assay

Full Title of Study: “Prospective Study to Evaluate Stretococcus Pneumoniae Serotype Prevalence in Community Acquired Pneumonia in Hong Kong Using a Urinary Kit”

Study Type

• Study Type: Observational
• Study Design
  • Time Perspective: Prospective
• Study Primary Completion Date: December 31, 2023

Interventions

• Diagnostic Test: urinary kit for pneumococcus antigen assay
  • urine test for detection of pneumococcus antigen

Clinical Trial Outcome Measures

Primary Measures

• prevalence of strep pneumonia
  • Time Frame: 2 years
  • to determine prevalence

Participating in This Clinical Trial

Inclusion Criteria

Admitted with signs and symptoms suggestive of pneumonia which include one or more of the followings: 1. fever 2. CXR changes with consolidation, increased alveolar shadowing or hazziness 3. respiratory symptoms like increase shortness of breath, cough with sputum Raised inflammatory markers suggesting of bacterial infection with either increased white cell count or C-reactive protein, or both Exclusion Criteria:

• Nosocomial pneumonia which is acquired >= 48 hours after hospital admission. Pneumonia which are already known to be caused by pathogens other than pneumococcus pneumoniae.

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Investigator Details

• Lead Sponsor
  • Chinese University of Hong Kong
• Provider of Information About this Clinical Study
  • Principal Investigator: To Kin Wang, Prof. – Chinese University of Hong Kong
• Overall Contact(s)
  • KW To, MBChB, 35052211, tokw617@yahoo.com.hk