German Cardiac Arrest Registry

Overview

In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes. Despite the medical progress over the last decades, rates of survival with good neurological outcome remain low. For many below-mentioned issues, no adequate evidence from randomized trials is available. Therefore, a systematic and standardized recording of the pre-clinical, clinical and post-clinical treatment course and of the clinical outcomes of OHCA patients is essential to improve patient care. Aim of the German Cardiac Arrest Registry (G-CAR) is to achieve a better understanding of the disease entity, leading to an optimized treatment of OHCA patients. The recorded data include information on demographic and psychosocial aspects, course of the disease, clinical, laboratory and other examinations as well as treatment modalities in patients with OHCA due to a cardiac cause.

Study Type

  • Study Type: Observational [Patient Registry]
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: June 30, 2023

Clinical Trial Outcome Measures

Primary Measures

  • In hospital mortality
    • Time Frame: until discharge, an average of 2 weeks

Secondary Measures

  • Length of ICU stay
    • Time Frame: until discharge, an average of 2 weeks
  • Length of hospital stay
    • Time Frame: until discharge, an average of 2 weeks
  • Mortality
    • Time Frame: Day 30
  • Mortality
    • Time Frame: Month 6
  • European Quality of Life 5 Dimensions 5 Level Version (EQ-5D)
    • Time Frame: Month 6
    • five levels in each dimension are worded as (1) ‘not /no problems’, (2) ‘slight problems’, (3) ‘moderate problems’, (4) ‘severe problems’, and (5) ‘unable to’
  • Post Traumatic Stress Syndrome
    • Time Frame: Month 6
    • PTSS-14
  • Reintegration
    • Time Frame: Month 6
    • Reintegration to Normal Living Index
  • Hospital Anxiety and Depression Scale (HADS)
    • Time Frame: Month 6
    • score 0-21; higher value show more severe depression
  • Mortality
    • Time Frame: Month 12
  • European Quality of Life 5 Dimensions 5 Level Version (EQ-5D)
    • Time Frame: Month 12
    • five levels in each dimension are worded as (1) ‘not /no problems’, (2) ‘slight problems’, (3) ‘moderate problems’, (4) ‘severe problems’, and (5) ‘unable to’
  • Post Traumatic Stress Syndrome (PTSS-14)
    • Time Frame: Month 12
    • scor 14-98; higher value indicate more post traumatic stress
  • Reintegration
    • Time Frame: Month 12
    • Reintegration to Normal Living Index
  • Hospital Anxiety and Depression Scale (HADS)
    • Time Frame: Month 12
    • score 0-21; higher value indicate more severe depression

Participating in This Clinical Trial

Inclusion Criteria

  • patients with out-of-hospital cardiac arrest with assumed cardiovascular cause Exclusion Criteria:

  • rejection of register participation by patient or legal representative

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Leipzig Heart Science gGmbH
  • Collaborator
    • Leipzig Heart Institute GmbH
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Janine Pöss, Dr., Study Chair, Heart Center Leipzig at University of Leipzig, Department of Internal Medicine/Cardiology
  • Overall Contact(s)
    • Janine Pöss, Dr., +49 341 865, janine.poess@medizin.uni-leipzig.de

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