68Ga-PSMA PET/CT Imaging in Assessment of Prostate Cancer
Overview
Dual-time point 68Ga-PSMA PET/CT could increase the lesion detection in PCa patients, it remains difficult to perform in clinical practice. The possibility of one-time point 68Ga-PSMA PET/CT imaging could be achieved using a total-body PET/CT.
Full Title of Study: “68Ga-PSMA PET/CT Imaging in Assessment of PCa: Feasibility of Delayed Acquisition on Total-body PET/CT Scanner?”
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: July 31, 2021
Interventions
- Device: total-body PET/CT
- PCa patients who underwent PSMA PET/CT in our clinical center received two-time points scans at 1 h p.i. and 3 h p.i. on a total-body PET/CT scanner.
Arms, Groups and Cohorts
- PCa patients underwent 1 h p.i. PSMA PET/CT imaging and 3 h p.i. PSMA imaging
Clinical Trial Outcome Measures
Primary Measures
- Only one-time point scan is possible for PSMA PET/CT
- Time Frame: 8 months
- By the use of total- body PET/CT scanner, the imaging quality between the 1 h p.i. and 3 h p.i. imaging acquisition are compared. And the different lesion detection rates at 3 h p.i. and 1 h p.i. are also discussed. The uptake value differences of all lesions are compared.
Participating in This Clinical Trial
Inclusion Criteria
- primary staging of pathology-confirmed PCa or evidence of BCR with PSA value > 0.2 ng/ml – positive 68Ga-PSMA findings – both standard and delayed scans were performed on the total-body PET/CT Exclusion Criteria:
- only one scan was performed – negative PSMA results
Gender Eligibility: Male
Minimum Age: N/A
Maximum Age: N/A
Are Healthy Volunteers Accepted: No
Investigator Details
- Lead Sponsor
- RenJi Hospital
- Provider of Information About this Clinical Study
- Principal Investigator: Yumei Chen, deputy head of the department of nuclear medicine – RenJi Hospital
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