68Ga-PSMA PET/CT Imaging in Assessment of Prostate Cancer


Dual-time point 68Ga-PSMA PET/CT could increase the lesion detection in PCa patients, it remains difficult to perform in clinical practice. The possibility of one-time point 68Ga-PSMA PET/CT imaging could be achieved using a total-body PET/CT.

Full Title of Study: “68Ga-PSMA PET/CT Imaging in Assessment of PCa: Feasibility of Delayed Acquisition on Total-body PET/CT Scanner?”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: July 31, 2021


  • Device: total-body PET/CT
    • PCa patients who underwent PSMA PET/CT in our clinical center received two-time points scans at 1 h p.i. and 3 h p.i. on a total-body PET/CT scanner.

Arms, Groups and Cohorts

  • PCa patients underwent 1 h p.i. PSMA PET/CT imaging and 3 h p.i. PSMA imaging

Clinical Trial Outcome Measures

Primary Measures

  • Only one-time point scan is possible for PSMA PET/CT
    • Time Frame: 8 months
    • By the use of total- body PET/CT scanner, the imaging quality between the 1 h p.i. and 3 h p.i. imaging acquisition are compared. And the different lesion detection rates at 3 h p.i. and 1 h p.i. are also discussed. The uptake value differences of all lesions are compared.

Participating in This Clinical Trial

Inclusion Criteria

  • primary staging of pathology-confirmed PCa or evidence of BCR with PSA value > 0.2 ng/ml – positive 68Ga-PSMA findings – both standard and delayed scans were performed on the total-body PET/CT Exclusion Criteria:

  • only one scan was performed – negative PSMA results

Gender Eligibility: Male

Minimum Age: N/A

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • RenJi Hospital
  • Provider of Information About this Clinical Study
    • Principal Investigator: Yumei Chen, deputy head of the department of nuclear medicine – RenJi Hospital

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