Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia

Overview

Administration of intravascular fluids is one of the methods to prevent SA-induced hypotension, but empirical intraoperative volume repletion carries the risk of fluid overload during elective surgery. Over fluid resuscitation is associated with organ dysfunction and higher mortality rate , thus, to avoid ineffective or even harmful intravascular volume expansion, it is important to have tools to predict hypotension and fluid responsiveness.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: February 1, 2022

Interventions

  • Diagnostic Test: ultrasound
    • Ultrasonographic measurement of Inferior Vena Cava Collapsibility Index

Clinical Trial Outcome Measures

Primary Measures

  • mean arterial blood pressure
    • Time Frame: 15 minutes after tourniquet release

Participating in This Clinical Trial

Inclusion Criteria

  • ASA grade I, II, III – Age 18 -65 yrs – Spinal Anesthesia Exclusion Criteria:

  • Patient refusal – Patient having contraindication of Spinal Anesthesia (infection at the site of injection, spine deformity, coagulation disorders ) . – Known cardiac, renal, neurological, metabolic, endocrine, psychiatric, respiratory disease.

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 65 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Ain Shams University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Mona Ammar, Assistant Professor – Ain Shams University

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.