Effect of Continuous Positive Air Way Pressure in Phase 1 Cardiac Rehabilitation After CABG

Overview

Different studies reported that CPAP is effective to prevent respiratory complication in post CABG patient and have greater impact on walking time, ventilatory function and breathing pattern.

Full Title of Study: “Effect of Continuous Positive Airway Pressure in Phase 1 Cardiac Rehabilitation After Post CABG”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: None (Open Label)
  • Study Primary Completion Date: February 27, 2020

Detailed Description

The walking time (6 minute walk test), effect on arterial blood gasses and long term effects of CPAP on cardiac activity, the previous studies focus only on the acute effects of CPAP along with specific exercises but did not tell about the long term effects. based on these finding this study is design to assess the effectiveness of CPAP in Post-op CABG patients regarding there early mobilization, walking time, ABGs and Ejection Fraction as there prognostic parameters in both phase-1 cardiac rehabilitation within hospital as well as in long-term prognosis, is of great interest.

Interventions

  • Other: Continuous Positive Air Way Group
    • CPAP between 10 and 12 cmH2O
  • Other: Control Group
    • Day 1: Bed mobility chest physiotherapy, active assistive ROM 5 repetitions of upper and lower limb, ACBT cycle. ABGS was analyses at first minute of exercise and vital was record after exercise. Day 2: Active range of motion exercise progress with 5 repetitions bed to chair mobility. same exercise progress with 5 repetition and 5 minute walk( day 3rd ).walking time will increase with 10 min at 4 day and at 5th day stair climbing the ABGS was record in ICU 3 days.

Arms, Groups and Cohorts

  • Experimental: Continuous Positive Air Way Group
    • Day 1: Use of CPAP between 10 and 12 cmH2O according to tolerance for 20 minutes two time a day at first day of post surgery bed mobility chest physiotherapy ,active assistive ROM 5 repetitions of upper and lower limb, ACBT cycle. ABGS was analyses at first minute of exercise. and vital was record after exercise. Day 2: Active ROM exercise progress of 5 repetitions bed to chair mobility. same exercise progress with 5 repetition and 5 minute walk( day 3rd ).walking time was increase with 10 min at 4 day and at 5th day stair climbing the ABGS was record in ICU 3 days.
  • Active Comparator: Control Group
    • Day 1: Bed mobility chest physiotherapy, active assistive ROM 5 repetitions of upper and lower limb, ACBT cycle. ABGS was analyses at first minute of exercise and vital was record after exercise. Day 2: Active range of motion exercise progress with 5 repetitions bed to chair mobility. same exercise progress with 5 repetition and 5 minute walk( day 3rd ).walking time will increase with 10 min at 4 day and at 5th day stair climbing the ABGS was record in ICU 3 days.

Clinical Trial Outcome Measures

Primary Measures

  • Arterial Blood Gasses
    • Time Frame: 3 days
    • measures oxygen and carbon dioxide levels in your blood. It also measures your body’s acid-base (pH) level, which is normally balanced when you are healthy.

Secondary Measures

  • 6 minute walk test
    • Time Frame: 3 days
    • gold standard test to measure exercise capacity and requires less physical space and allows for easier monitoring of vital parameters
  • Ejection Fraction
    • Time Frame: 4 week
    • expressed as a percentage, of how much blood the left ventricle pumps out with each contraction.
  • Sf12 Questionnaire
    • Time Frame: 4 weeks
    • measuring tool for mental and physical health components. It consists of 12 questions which cover the eight health domain with one or two question per domain

Participating in This Clinical Trial

Inclusion Criteria

  • age between 35 to 60 years. – With a clinical diagnosis of coronary artery disease, underwent elective CABG (Acute) Exclusion Criteria:

  • Low ejection friction (15%) – Patient those who have any arrhythmias – Unstable angina – Patient having pace maker and implantable cardioverter defibrillator – COPD and asthmatic patient – Patient having BMI more then 40

Gender Eligibility: Male

clinical diagnosis of coronary artery disease, underwent elective CABG (Acute)

Minimum Age: 35 Years

Maximum Age: 65 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Riphah International University
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Sumaiyah Obaid, MS, Principal Investigator, Riphah International University

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