Photobiomodulation Therapy Combined With Static Magnetic Field on the Subsequent Performance

Overview

There is evidence about the effects of photobiomodulation therapy (PBMT) alone and combined with static magnetic field (PBMT-sMF) on skeletal muscle fatigue, physical performance and post-exercise recovery in different types of exercise protocols and sports activity. However, it is unknown the effects of PBMT-sMF to improve the subsequent performance after a first set of exercise. Therefore, the aim of this study was to investigate the effects of PBMT-sMF, applied between two sets of exercises, on the subsequent physical performance.

Full Title of Study: “Immediate Effects of Photobiomodulation Therapy Combined With Static Magnetic Field on the Subsequent Performance: a Randomized Crossover Triple-blinded Placebo-controlled Trial”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Crossover Assignment
    • Primary Purpose: Prevention
    • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Study Primary Completion Date: September 2015

Detailed Description

A randomized, crossover, triple-blinded (assessors, therapist and volunteers), placebo-controlled trial was carried out. Healthy non-athletes' male volunteers were randomized and treated with a single application of PBMT-sMF and placebo between two sets of an exercise protocol performed on isokinetic dynamometer. The order of interventions was randomized. The primary outcome was fatigue index, measured by isokinetic dynamometer during the exercise protocol. The secondary outcomes were total work and peak torque measured by isokinetic dynamometer during the exercise protocol; and blood lactate, measured by blood samples collected before, 3 minutes after the first set of the exercise protocol, 3 minutes after the application of the intervention and 3 minutes after the second set of the exercise protocol. Statistical analysis: The findings were tested for normality using the Kolmogorov-Smirnov test and were determined to have a normal distribution. Data were expressed as the mean and standard deviation, and a two-way repeated measures ANOVA was performed to test between-group differences at each timepoint (treatment effects), mean difference (MD) and 95% confidence intervals (CI), followed by the Bonferroni post hoc test. The significance level was set at p < 0.05.

Interventions

  • Device: Active PBMT-sMF
    • PBMT-sMF was applied employing the Multi Radiance Medical Super Pulsed Laser MR4 console (Solon, Ohio, USA) with a LaserShower cluster probe as emitter. Six different sites of the knee extensor muscles (two medial, two lateral and two central points) were irradiated at the same time.
  • Device: Placebo PBMT-sMF
    • Placebo PBMT-sMF was applied employing the Multi Radiance Medical Super Pulsed Laser MR4 console (Solon, Ohio, USA) with a LaserShower cluster probe as emitter, but without any emission of therapeutic dose. Placebo PBMT-sMF was applied at six different sites of the knee extensor muscles (two medial, two lateral and two central points).

Arms, Groups and Cohorts

  • Experimental: PBMT-sMF
    • Volunteers underwent intervention (active PBMT-sMF) in the non-dominant lower limb. A single application was performed at each phase of the trial, between the first and second set of the exercise protocol.
  • Placebo Comparator: Placebo
    • Volunteers underwent intervention (placebo PBMT-sMF) in the non-dominant lower limb. A single application was performed at each phase of the trial, between the first and second set of the exercise protocol.

Clinical Trial Outcome Measures

Primary Measures

  • Fatigue index
    • Time Frame: 1 minute after the end of exercise protocol.
    • Variable provided directly by the isokinetic dynamometer during the exercise protocol.

Secondary Measures

  • Total work
    • Time Frame: 1 minute after the end of exercise protocol.
    • Variable provided directly by the isokinetic dynamometer during the exercise protocol.
  • Peak torque
    • Time Frame: 1 minute after the end of exercise protocol.
    • Variable provided directly by the isokinetic dynamometer during the exercise protocol.
  • Blood lactate
    • Time Frame: 3 minutes after the first set of the exercise protocol, 3 minutes after the application of the intervention and 3 minutes after the second set of the exercise protocol.
    • Measured by blood samples.

Participating in This Clinical Trial

Inclusion Criteria

  • Male healthy volunteers; – Non-athletes or those who practiced physical activity up to once a week; – Aged 18-35 years. Exclusion criteria – History of musculoskeletal injuries in the hip and knee regions in the two months prior to the study; – Use of pharmacological agents and nutritional supplements; – Chronic joint disease in the non-dominant lower limb.

Gender Eligibility: Male

Minimum Age: 18 Years

Maximum Age: 35 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • University of Nove de Julho
  • Provider of Information About this Clinical Study
    • Principal Investigator: Ernesto Cesar Pinto Leal Junior, Full professor – University of Nove de Julho

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