We conducted a retrospective study of critical ill patients who used ECMO during their ICU stay. ICU-AW was diagnosed at the time when patients discharged and had a Medical Research Council (MRC) sum score < 48 out of a maximal score of 60. We divided patients to ICU-acquired weakness group and no ICU-acquired weakness group and compared their clinical characteristics. Baseline characteristics and therapy details were collected from the case report forms and inspection reports. Univariable analysis and logistic regression analysis were used to analyze clinical characteristics of individuals and to find risk factors of ICU-AW.
Full Title of Study: “ICU-acquired Weakness in Extracorporeal Membrane Oxygenation Support: Frequency and Risk Factors”
- Study Type: Observational
- Study Design
- Time Perspective: Other
- Study Primary Completion Date: March 1, 2020
Arms, Groups and Cohorts
- ICU-acquired weakness group
- Patients receiving extracorporeal membrane oxygenation support who had a Medical Research Council (MRC) sum score < 48 out of a maximal score of 60 when discharged.
- no ICU-acquired weakness group
- Patients receiving extracorporeal membrane oxygenation support who had a Medical Research Council (MRC) sum score ≥ 48 out of a maximal score of 60 when discharged.
Clinical Trial Outcome Measures
- Differences between ICU-acquired weakness in patients receiving extracorporeal membrane oxygenation support
- Time Frame: 1 day
- We compared the clinical characteristics between ICU-acquired weakness group and no ICU-acquired weakness group by univariate analysis . Then we used logistic regression analysis and found out differences of ICU-acquired weakness.
- Frequency of ICU-acquired weakness in in patients receiving extracorporeal membrane oxygenation support
- Time Frame: 1 day
- We calculated the prevalence of ICU-acquired weakness on the patients included in our research.
Participating in This Clinical Trial
- Critical ill patients who used extracorporeal membrane oxygenation during their ICU stay. Patients were recruited from the general ICU of the second affiliated hospital of Zhejiang University, between March 2017 to March 2020. Exclusion Criteria:
- Patients who was less than 18 years old, had been proven or suspected neurological impairment, using extracorporeal membrane oxygenation less than 24 hours, severe head or spinal cord injury and pregnant woman.
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 80 Years
Are Healthy Volunteers Accepted: No
- Lead Sponsor
- Second Affiliated Hospital, School of Medicine, Zhejiang University
- Provider of Information About this Clinical Study
- Overall Contact(s)
- xinyi chen, master, 19858875700, email@example.com
Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.