Irisin Expression and Gene Polymorphism With Peripartum Cardiomyopathy.

Overview

this is an observertional study aimed at Study the association between the level of irisin expression and (Fibronectin Type III Domain Containing 5 (FDNC5) gene polymorphism in female patients with peripartum cardiomyopathy.

Full Title of Study: “FDNC5 Genetic Polymorphism in Patients With Peripartum Cardiomyopathy”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: January 30, 2022

Arms, Groups and Cohorts

  • Diseased
    • Females with peripartum cardiomyopathy
  • Control
    • Healthy females

Clinical Trial Outcome Measures

Primary Measures

  • Irisin level
    • Time Frame: 4 months
    • detect the serum level of irisin hormone by ELIZA in nanogram/decilitre(ng/dl)
  • FNDC5 Genotyping
    • Time Frame: 4 months
    • whether homogenetic or heterogenetic

Participating in This Clinical Trial

Inclusion Criteria

  • This study will include females aged between 18 and 45 years old who have been diagnosed and treated clinically for peripartum cardiomyopathy Exclusion Criteria:

  • Age less than 18 or more than 45 year old – females with dilated cardiomyopathy due to other etiology or outside the time frame of occurrence of peripartum cardiomyopathy

Gender Eligibility: Female

the studied disease peripartum cardiomyopathy is female specific

Minimum Age: 18 Years

Maximum Age: 45 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Sohag University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Ali Mohamed Ahmed Altaher, clinical professor – Sohag University
  • Overall Contact(s)
    • Ali mo Altaher, lecturer, 01003376529, dr.ali.altaher30@gmail.com

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