Compare the Quadriceps Function of Adductor Canal Block Versus Femoral Nerve Block With Electromyography Following Total Knee Arthroplasty


Adductor canal block and femoral nerve block are the most commonly used nerve blocks for pain control after total knee arthroplasty. The block area for adductor canal is a sensory branch near the knee area, which can potentially reduce the effect of motor blockage of quadriceps muscle. We try to proof adductor canal block can reduce the pain level after surgery effectively and preserve the muscle power of quadriceps muscle. Therefore, the rehabilitation course can be reduced and further lowering the risks of falling and complications.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: Double (Participant, Care Provider)
  • Study Primary Completion Date: March 31, 2022


  • Procedure: Nerve block
    • Two different nerve block types, Adductor canal block group and Femoral nerve block group

Arms, Groups and Cohorts

  • Experimental: Adductor canal block group
    • Adductor canal block group
  • Experimental: Femoral nerve block group
    • Femoral nerve block group

Clinical Trial Outcome Measures

Primary Measures

  • Quadriceps muscle Electromyography voltage level change before and after nerve block
    • Time Frame: compare difference of Quadriceps muscle Electromyography voltage level 12 weeks after surgery,data were measured post operation day 1, day 2, day 5, 2 weeks, 6 weeks and 12 weeks
    • surface electromyography level

Participating in This Clinical Trial

Inclusion Criteria

  • Age at least 50 years old, not exceed 100 years old – Diagnosed Primary Knee Osteoarthritis – Accepted Total Knee Arthroplasty Exclusion Criteria:

  • Diagnosed Osteonecrosis – Diagnosed inflammatory Arthritis、Rheumatoid Arthritis – Accepted Revision Total Knee Arthroplasty – Quadriceps muscle rupture, suture or repair history – Neurological or orthopedic disorders that could affect quadriceps muscle power – Allergy to amide anesthetics – Patients who cannot obey or follow directions

Gender Eligibility: All

Minimum Age: 50 Years

Maximum Age: 100 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Kaohsiung Medical University Chung-Ho Memorial Hospital
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Hsuan-Ti Huang, M.D, Study Director, Kaohsiung Medical University
  • Overall Contact(s)
    • Ying-Chun Wang, M.D, 886-07-3121101,

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