Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow’s Milk in Children

Overview

The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female. They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk)

Full Title of Study: “Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow’s Milk in Children”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: N/A
    • Intervention Model: Single Group Assignment
    • Primary Purpose: Other
    • Masking: None (Open Label)
  • Study Primary Completion Date: January 17, 2020

Detailed Description

– The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female. – The group was given a brushing technique using a model and 2 videos were shown to reinforce the brushing technique and explanation of what was going to be done in the study. – Supervised tooth brushing was performed in a group of 5 people. – They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk). – Each child was given 7 plastic cups each day and asked to pour their saliva into the cup when instructed. – The samples were taken with pH indicator strips and the result was recorded in personalized tables.

Interventions

  • Dietary Supplement: Comparison of salivary pH after consuming milk of origin vegetable vs cow’s milk
    • They were given 5 types of milk, each one was measured on different days (Monday cow’s milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk).

Arms, Groups and Cohorts

  • Experimental: pH milk
    • Group of children who were given the different types of milk and only the pH was measured

Clinical Trial Outcome Measures

Primary Measures

  • Sociodemographic results
    • Time Frame: 1 hour the sociodemographic data of all the children were taken.
    • The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female.
  • pH results
    • Time Frame: The average time of pH evaluation for each milk per child was an hour and a half.
    • 30 minutes after tooth brushing, each child was asked for the first saliva sample (basal pH measurement). After taking the basal pH, each child was given a glass with 50 ml of the milk to be measured. Saliva samples were measured with pH indicator strips and the result was recorded on custom charts. The pH was taken at 5, 10, 20, 30, 40 and 50 minutes. The normality distribution test (Shapiro-Wilk) was applied to the quantitative variables, with p = 0.0001, so that the data present a non-parametric or free distribution. To assess whether there were differences between the pH of the groups, the Kuskal-Wallis test was applied. For basal pH, p = 0.0001, therefore the null hypothesis is rejected and we conclude that the basal pH level is different in the five milks. Average basal pH: Rice milk 7 Cow milk 6.9 Almond milk 6.6 Soy milk 6.4 Coconut milk 6

Participating in This Clinical Trial

Inclusion Criteria

  • Boys and girls from 3 to 6 years Exclusion Criteria – Boys and girls with allergies – Children with lactose intolerance Elimination criteria: – Boys and girls who do not want to participate at the time of the study

Gender Eligibility: All

Minimum Age: 3 Years

Maximum Age: 6 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Universidad Tecnologica de Mexico
  • Provider of Information About this Clinical Study
    • Principal Investigator: Annia Marisol Avalos Mejía, Principal Investigator – Universidad Tecnologica de Mexico
  • Overall Official(s)
    • Annia Avalos, Master, Principal Investigator, Universidad Tecnológica Centroamericana

References

Vanga SK, Raghavan V. How well do plant based alternatives fare nutritionally compared to cow's milk? J Food Sci Technol. 2018 Jan;55(1):10-20. doi: 10.1007/s13197-017-2915-y. Epub 2017 Nov 2. Review.

Hettinga K, van Valenberg H, de Vries S, Boeren S, van Hooijdonk T, van Arendonk J, Vervoort J. The host defense proteome of human and bovine milk. PLoS One. 2011 Apr 27;6(4):e19433. doi: 10.1371/journal.pone.0019433.

Cuppari C, Manti S, Salpietro A, Dugo G, Gitto E, Arrigo T, Sturiale M, Salpietro C. ALMOND MILK: A POTENTIAL THERAPEUTIC WEAPON AGAINST COW'S MILK PROTEIN ALLERGY. J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2 Suppl 1):8-12.

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