Surgical Treatment of Gingival Recessions

Overview

The purpose of this study was to compare the effectiveness of microsurgical and macrosurgical approaches on CPFs plus SCTGs for the treatment of localized gingival recession defects (Miller class I or II) over the course of 6 months based on clinical periodontal parameters, periodontal phenotypes, and the postoperative complaints and satisfaction levels of the patients. We hypothesized that root coverage achieved through microsurgery in Miller I or II gingival recessions would improve clinical periodontal outcomes and the periodontal phenotype, with greater postoperative comfort and aesthetic satisfaction in comparison with conventional macrosurgical techniques. Miller Class I and II gingival recession defects, at least 3.0 mm deep, were selected and randomly assigned to receive micro or macrosurgical techniques. Both techniques were performed using a coronally positioned flap with a subepithelial connective tissue graft. Plaque and gingival indices, gingival recession depth and width, probing pocket depth, bleeding on probing, clinical attachment level, width of keratinized gingiva, aesthetic score and percentage of root coverage, postoperative complaints, and satisfaction of the participants completing the study were evaluated at follow-up 1st, 3rd and 6th months.

Full Title of Study: “Micro and Macrosurgical Treatment of Gingival Recessions: a Randomized Clinical Trial”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: Double (Participant, Outcomes Assessor)
  • Study Primary Completion Date: May 2017

Interventions

  • Procedure: surgical techniques in the treatment of localized gingival recession defects.
    • Micro or macrosurgical echniques were performed using a coronally positioned flap with a subepithelial connective tissue graft.

Arms, Groups and Cohorts

  • Experimental: Microsurgery group
    • All defects were treated with a CPF plus an SCTG by the same investigator using microsurgery technique.
  • Active Comparator: Macrosurgery group
    • All defects were treated with a CPF plus an SCTG by the same investigator using macrosurgery technique.

Clinical Trial Outcome Measures

Primary Measures

  • Percentage of root coverage
    • Time Frame: 6 months
    • The primary endpoint for efficacy of the gingival recession was the percentage of root coverage at baseline and 6-months postsurgery, as measured by gingival recession depth.

Secondary Measures

  • Changes in Gingival recession depth
    • Time Frame: 6 months
  • Changes in Gingival recession width
    • Time Frame: 6 months
  • Changes in Keratinized gingival width
    • Time Frame: 6 months
  • visual analog scale
    • Time Frame: 6 months
    • A visual analog scale was used to evaluate postoperative complaints regarding the recipient and donor sites according to graft size and postoperative satisfaction values (level of the gingival margin, gingival tissue color, dentin hypersensitivity, and root coverage) during the follow-up period. A 10 cm VAS, with “none” / “unhappy” at the left end and “unbearable” / “happy” at the right end was prepared for each patient.

Participating in This Clinical Trial

Inclusion Criteria

- All participants were:

  • adults aged 18 years or over – systemically and periodontally healthy – met the eligibility criteria for localized gingival recession of the canine or premolar teeth according to the Miller classification scheme Exclusion Criteria:

- Exclusion criteria included the following:

  • medical disorders such as diabetes mellitus, immunologic disorders, and hepatitis; – a history of chemotherapy or radiotherapy; – a history of alcoholism or drug abuse; – a history of previous mucogingival surgery at the gingival recession site; – medications known to affect gingival tissues; – antibiotic treatment in the past 6 months; – smoking >10 cigarettes per day for >5 years, and; – current pregnancy or lactation.

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 65 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Istanbul Medipol University Hospital
  • Collaborator
    • Kocaeli University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Begum Alkan, Periodontology specialist – Istanbul Medipol University Hospital

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