The Reflex Mechanism Underlying Neuromuscular Effects Of The Whole Body Vibration

Overview

This study was conducted to determine whether the spinal reflex mechanism underlying the neuromuscular effects of whole body vibration (WBV) is tonic vibration reflex. Local and whole body vibration reflex latencies were measured in young adult healthy volunteers.

Full Title of Study: “The Reflex Mechanism Underlying The Neuromuscular Effects Of The Whole Body Vibration”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: N/A
    • Intervention Model: Single Group Assignment
    • Primary Purpose: Basic Science
    • Masking: None (Open Label)
  • Study Primary Completion Date: October 7, 2020

Detailed Description

A total of eight volunteers were included according to the inclusion and exclusion criteria. The subjects were vibrated while standing upright with the WBV device (PowerPlate® Pro5). The 30, 35 and 40 Hz WBVs were applied for thirty seconds for each frequency with an amplitude of 2 mm. In the same session, 100, 135 and 150 Hz local vibrations were applied to the right Achilles tendon for thirty seconds for each frequency. 100, 135 and 150 Hz local vibrations were then applied to the right heel for thirty seconds for each frequency with an interval of five seconds. Vibration stimuli were recorded accelerometers. Reflex muscle responses were recorded from the right soleus muscle at a sampling rate of 40 KHz. Recording electrodes were placed on the belly of the right soleus muscle and the ground electrode was placed on the right medial malleolus. The data were recorded with the PowerLab device, the records were processed and analyzed offline from the LabChart program. After the EMG records are filtered and rectified, reflex latencies were measured by cumulative averaging method using the accelerometer records as triggers (Karacan I, Cakar HI, Sebik O, Yilmaz G, Cidem M, Kara S, Türker KS.A new method to determine reflex latency induced by high rate stimulation of the nervous system.Front Hum Neurosci.2014 Jul 18; 8: 536.doi: 10.3389 / fnhum.2014.00536). After determining the Achilles tendon vibration reflex latency and the reflex latency induced by WBV, it was compared with statistical methods.

Interventions

  • Other: vibration
    • local and whole-body vibration were applied

Arms, Groups and Cohorts

  • Experimental: Experiment
    • Local and whole body vibration were applied

Clinical Trial Outcome Measures

Primary Measures

  • reflex latency
    • Time Frame: during intervention, an average of 8 minutes
    • The time between the vibration stimulus and the reflex muscle response triggered by it was defined as the latency.

Participating in This Clinical Trial

Inclusion Criteria

  • Healthy – Young adult (20-40 years old) – Both gender – Volunteer Exclusion Criteria:

  • Cardiac disorder (Rhythm / conduction disorder, Cardiac pacemaker, Ischemic heart disease) – Finding or suspected active deep vein thrombosis, – History of deep vein thrombosis and pulmonary embolism, – Orthostatic hypotension – Hypertension – Presence of fracture in the lower limb – Achilles Contractures – Active inflammatory, rheumatological or infectious disease in the lower limb – Peripheral nerve lesions such as polyneuropathy, radiculopathy in the lower limb – Those with a history of Achilles tendinopathy / bursitis – Those with a history of kidney stones – Patients with dizziness and balance problems, – Cases with lesions on the skin surface where electrodes were attached – Those with communication-cooperation problems – Having a history of panic attacks

Gender Eligibility: All

Minimum Age: 20 Years

Maximum Age: 40 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Istanbul Physical Medicine Rehabilitation Training and Research Hospital
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Ilhan Karacan, Assoc Prof, Principal Investigator, Istanbul Physical Medicine Rehabilitation Training & Research Hospital

Citations Reporting on Results

Yildirim MA, Topkara B, Aydin T, Paker N, Soy D, Coskun E, Ones K, Bardak A, Kesiktas N, Ozyurt MG, Celik B, Onder B, Kilic A, Kucuk HC, Karacan I, Turker KS. Exploring the receptor origin of vibration-induced reflexes. Spinal Cord. 2020 Jun;58(6):716-723. doi: 10.1038/s41393-020-0419-5. Epub 2020 Jan 15.

Aydin T, Kesiktas FN, Baskent A, Karan A, Karacan I, Turker KS. Cross-training effect of chronic whole-body vibration exercise: a randomized controlled study. Somatosens Mot Res. 2020 Jun;37(2):51-58. doi: 10.1080/08990220.2020.1720635. Epub 2020 Feb 5.

Karacan I, Cakar HI, Sebik O, Yilmaz G, Cidem M, Kara S, Turker KS. A new method to determine reflex latency induced by high rate stimulation of the nervous system. Front Hum Neurosci. 2014 Jul 18;8:536. doi: 10.3389/fnhum.2014.00536. eCollection 2014.

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.