Effect of Daily Doses of Rice or Whey Protein on Resistance Training Adaptations


The purpose of this study is to compare the ability of isocaloric and isonitrogenous (2 x 15-gram) doses of rice protein or whey protein to stimulate resistance training adaptations in young, healthy, resistance-trained men.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Other
    • Masking: Double (Participant, Investigator)
  • Study Primary Completion Date: February 12, 2020

Detailed Description

The study will be conducted using a randomized, double-blind approach with individuals being provided two doses of either 15 grams of rice or 15 grams of whey protein over an 8-week supplementation period while completing a heavy resistance training. One dose will be ingested within one hour of completing each workout and the other dose will be ingested within an hour of going to bed. On non-workout days, one dose of 30 grams will be ingested within 60 minutes of going to bed. The resistance training protocol will follow a linear periodization, split-body resistance training design consisting of two upper body and two lower body workouts each week resulting in each muscle group being trained twice each week. To minimize the influence of training experience and any learning effect, individuals with at least 12 months of resistance training history will be recruited. Participants will also be required to complete a two-week lead-in period (8 total workouts) before beginning the supplementation regimen to become accustomed to the training program and to account for any early neurological adaptations. Participants will then continue to follow the resistance training program for an additional 8 weeks. To assess the efficacy of the two different forms of protein supplementation on resistance training adaptations, changes in fat-free, lean, and fat mass will be determined using DEXA. Maximal strength and endurance of both upper and lower-body muscle groups will be determined while anaerobic capacity markers will be measured with the completion of a Wingate anaerobic capacity test. Participants will also be provided nutritional recommendations in order to ensure adequate energy and macronutrient consumption to facilitate positive training adaptations and eliminate any potential influence of differing dietary intakes.


  • Dietary Supplement: Whey Protein
    • Each condition (both rice and whey protein) match in color, flavor, and serving size.

Arms, Groups and Cohorts

  • Active Comparator: Rice Protein
    • Rice Protein – 24 grams, chocolate, powder
  • Active Comparator: Whey Protein
    • Whey Protein – 24 grams, chocolate, powder

Clinical Trial Outcome Measures

Primary Measures

  • Changes in upper- and lower-body strength via Dual-Energy X-ray Absorptiometry
    • Time Frame: Eight weeks
    • Examining how much strength each participant gains (or loses) from Day 1 to Final day
  • Changes in fat-free mass via Dual-Energy X-ray Absorptiometry
    • Time Frame: Eight weeks
    • Examining the differences in fat-free mass from Day 1 to Final day

Secondary Measures

  • Changes in muscular endurance by counting repetitions for each exercise test
    • Time Frame: Eight weeks
    • Examining the differences in muscular endurance from Day 1 to Final day
  • Changes in resistance training volume by tracking how many pounds were lifted during each exercise
    • Time Frame: Eight weeks
    • Examining the differences in resistance training volume from Day 1 to Final day

Participating in This Clinical Trial

Inclusion Criteria

  • Between the ages of 18-50 years, although it is anticipated that the majority of participants will be between 18 and 35 years of age. – Participants will be healthy and free of disease as determined by evaluation of a medical history – All participants will be required to abstain from taking any additional forms of nutritional supplementation (preworkouts, creatine, beta-alanine, etc.) for four weeks prior to beginning this study and for the entire duration of the study. Exclusion Criteria:

  • Those individuals with less than 12 months of structured resistance training experience will be excluded from the study. – Individuals whose maximal relative upper body strength is below 1.0 will be excluded. – Individuals whose maximal relative lower body strength is below 1.50 will be excluded. – As indicated on a medical history form they complete, any individual who is currently being treated for or diagnosed with a cardiac, respiratory, circulatory, musculoskeletal, metabolic, obesity (defined as body mass index > 30 kg/m2 and body fat greater than 30%), immune, autoimmune, psychiatric, hematological, neurological or endocrinological disorder or disease will be excluded. – Those individuals who present with any previous injury or illness that would prevent them from appropriately completing all exercise lifts will be excluded from the study. – Participants who are not able to fit onto the DEXA table will not be able to participate in the research due to size restrictions of the equipment. This typically includes individuals exceeding 300 pounds or those greater than 6 feet 6 inches. – Those individuals less than 18 and greater than 50 years of age will be excluded. Participants younger than 18 are excluded due to necessity of parental consent. Participants greater than 50 years old lie outside of the target demographic for the current study. – Participants who are determined to not be weight stable defined as week 0 and week 2 body mass levels deviating by 2% or more.

Gender Eligibility: Male

Minimum Age: 18 Years

Maximum Age: 50 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Lindenwood University
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Chad Kerksice, PhD, Study Director, Laboratory Director

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