The Influence of Suture Method in Conjunctival Autograft Transplantation on Postoperative Ocular Discomfort for Primary Pterygium


To evaluate the efficacy and effect on patient comfort of a hidden-knot continuous suture for pterygium excision with conjunctival autograft,compared with two-knot continuous sutures and multi-knot interrupted sutures.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: Double (Participant, Outcomes Assessor)
  • Study Primary Completion Date: November 21, 2020


  • Procedure: suture
    • suture methods of autograft conjunctival transplantation

Arms, Groups and Cohorts

  • Experimental: hidden-knot group
  • Active Comparator: two-knot group
  • Active Comparator: multi-knot group

Clinical Trial Outcome Measures

Primary Measures

  • Patient comfort
    • Time Frame: 6 months
    • discomfort grading on a visual analog scale

Participating in This Clinical Trial

Inclusion Criteria

  • patients with primary pterygium

Exclusion Criteria

  • eye surgery history
  • acute ocular surface imflamation
  • patients with coagulation or diabetes mellitus

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 80 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Aier School of Ophthalmology, Central South University
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Contact(s)
    • Yan Chen, doctor, +86-021-62956699,

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