Egg Consumption and Muscular Adaptations

Overview

Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.

The investigators hypothesis is that whole eggs would create a greater improvement in skeletal regulatory markers, hormonal responses and body composition than egg white ingestion in resistance-trained men.

Full Title of Study: “Comparison of Whole Eggs vs. Egg Whites Consumption on Regulatory Myokines, Muscular Strength, Hypertrophy, Power and Body Composition.”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Basic Science
    • Masking: Single (Investigator)
  • Study Primary Completion Date: October 2, 2019

Detailed Description

The aim of this investigation was to compare the effects of whole egg versus egg white ingestion (daily and after training sessions) during 12 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to:

To investigate the extent to which both whole egg and egg white ingestion will improve anabolic factors, fat free mass, fat mass and decrease catabolic markers after 12 weeks of resistance training in resistance-trained men.

Interventions

  • Dietary Supplement: Whole egg and resistance training
    • This intervention consisted of whole egg consumption concomitant with 12 weeks of resistance training. Subject ingested three whole eggs per day immediately after resistance training.
  • Dietary Supplement: Egg whites and resistance training
    • This intervention consisted of egg white consumption concomitant with 12 weeks of resistance training. Subject ingested an isonitrogenous quantity of six egg whites per day immediately after resistance training.

Arms, Groups and Cohorts

  • Experimental: Whole egg consumption
    • This arm involved whole egg consumption concomitant with 12 weeks of resistance training. Subject ingested three whole eggs per day immediately after resistance training.
  • Experimental: Egg whites consumption
    • This arm involved egg white consumption concomitant with 12 weeks of resistance training. Subject ingested an isonitrogenous quantity of six egg whites per day immediately after resistance training.

Clinical Trial Outcome Measures

Primary Measures

  • Circulatory Myokines levels
    • Time Frame: 12 weeks
    • Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentration of myostatin, follistatin, FGF-2, TGF-β1 and ACVA.
  • Circulatory hormone levels
    • Time Frame: 12 weeks
    • Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentrations of testosterone, IGF-1, insulin and cortisol
  • Muscle mass
    • Time Frame: 12 weeks
    • Skeletal muscle mass will be evaluated using computed tomography
  • Body fatness
    • Time Frame: 12 weeks
    • Body fat will be evaluated using bioelectrical impedance

Secondary Measures

  • Muscular Strength
    • Time Frame: 12 weeks
    • Using 1 repetition maximum

Participating in This Clinical Trial

Inclusion Criteria

  • performing resistance training at least three times a week for 1 year prior to the start of the study
  • not taking any dietary supplements or medications for at least 1 year prior to the start of the study
  • no known medical issues
  • no alcohol consumption or smoking for at least 1 year prior to the start of the study
  • no egg allergy/sensitivity.

Exclusion Criteria

  • non-willingness to continue nutritional or exercise protocols
  • participation in exercise other than the prescribed resistance training program
  • consumption of dietary supplement (other than egg) during the study period
  • Missing more than one resistance training session or post-exercise egg consumption throughout the study period

Gender Eligibility: Male

Minimum Age: 18 Years

Maximum Age: 30 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Alexei Wong
  • Collaborator
    • Tehran University
  • Provider of Information About this Clinical Study
    • Sponsor-Investigator: Alexei Wong, Assistant Professor – Marymount University
  • Overall Official(s)
    • Alexei Wong, Principal Investigator, Marymount University

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