Characterization of Cardiovascular Diseases and Risk Factors in Patients With Suspected SARS-CoV2/Covid-19 Infection


The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects host-cells via ACE2-receptors, which leads to pneumonia (COVID-19) but also can lead to myocarditis (acute myocardial injury) and chronic damage to the cardiovascular system. Therefore, cardiovascular protection may be necessary when treating patients with COVID-19 infection. This may especially be necessary in patients with cardiovascular diseases, risk factors, and co-medication.

Study Type

  • Study Type: Observational [Patient Registry]
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: March 25, 2026


  • Diagnostic Test: Assessment of cardiovascular diseases and cardiovascular risk factors
    • At inclusion, patients will be screened for pre-existing cardiovascular diseases and cardiovascular risk factors, as well as medication.

Clinical Trial Outcome Measures

Primary Measures

  • All-cause mortality
    • Time Frame: During 1 year follow-up
    • mortality of any cause

Secondary Measures

  • 30-day mortality
    • Time Frame: Within 30 days after inclusion
    • mortality of any cause
  • Major adverse cardiovascular events
    • Time Frame: During 1 year follow-up
    • Myocardial infarction, stroke, or CV death

Participating in This Clinical Trial

Inclusion Criteria

  • Patients with suspected SARS-CoV2/Covid-19 infection Exclusion Criteria:

  • Unwillingness to participate

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • University Hospital, Essen
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Tienush Rassaf, MD, Principal Investigator, University Hospital Essen, Deparment of Cardiology and Vascular Medicine
  • Overall Contact(s)
    • Matthias Totzeck, MD, +49201723,

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