Prolactin Hormone in Rheumatoid Arthritis Patients With Periodontitis

Overview

In this study we will assess the presence of prolactin hormone in the gingival crevicular fluid , and synovial fluid of patient with rheumatoid arthritis and periodontitis

Full Title of Study: “Synovial and Gingival Crevicular Fluid Levels of Prolactin Hormone in Rheumatoid Arthritis Patients With Periodontitis”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: April 2020

Arms, Groups and Cohorts

  • periodontitis and rheumatoid arthritis
    • group 1: patiernts with periodontitis and rheumatoid arthritis. only
  • periodontitis
    • group 2: patiernts with periodontitis

Clinical Trial Outcome Measures

Primary Measures

  • prolactin hormone levels in the tested media
    • Time Frame: 24 hours
    • changes in prolactin hormone expression in the tested media

Participating in This Clinical Trial

Inclusion Criteria

  • for first group patients with active rheumatoid arthritis with periodontitis. – second group , patients with periodontitis and otherwise systemically healthy – third group, systemically and periodontallly healthy subjects Exclusion Criteria:

  • smokers, – pregnant or lactating females – patients taking medications the affects levels of prolactin hormone. – no periodontal treatment in the past six months

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 60 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • October University for Modern Sciences and Arts
  • Provider of Information About this Clinical Study
    • Principal Investigator: Naglaa Elwakeel, professor – October University for Modern Sciences and Arts
  • Overall Contact(s)
    • Naglaa El-Wakeel, 01001757761, naglaelwakeel@gmail.com

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