Corneal Densitometry Changes With Adenoviral SEI

Overview

Adenoviral Sub epithelial infiltrates (SEI) affect ocular function.They lead to reduced vision, photophobia, glare, halos, and foreign body sensation.

Full Title of Study: “Corneal Densitometry Changes With Adenoviral Keratoconjunctivitis Sub Epithelial Infiltrates”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: April 1, 2020

Detailed Description

first group of patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.S econd group underwent transepithelial PTK for subepithelial infiltrates. Baseline and post-treatment full ophthalmic examination was done.

Interventions

  • Drug: Tacrolimus ointment
    • Patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.
  • Procedure: phototherapeutic keratectomy
    • Patients underwent transepithelial PTK for subepithelial infiltrates.

Arms, Groups and Cohorts

  • Tacrolimus
    • Patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.
  • Phototherapeutic Keratectomy
    • Patients underwent transepithelial PTK for subepithelial infiltrates.
  • Control
    • patients received only artificial tears eyedrop

Clinical Trial Outcome Measures

Primary Measures

  • changes of corneal densitometry
    • Time Frame: 6 months
    • Sub epithelial infiltrates was examined with the densitometry programme of the Pentacam (Fa. Oculus,Weimar, Germany)

Participating in This Clinical Trial

Inclusion Criteria

  • adenoviral SEI Exclusion Criteria:

  • Other corneal diseases

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 75 Years

Investigator Details

  • Lead Sponsor
    • Benha University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Tarek Roshdy mohamed Mahgoub ELhamaky, Lecturer – Benha University
  • Overall Official(s)
    • TAREK R ELHAMAKY, Principal Investigator, Benha university faculty of medicine

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