Adult-onset Generalized Morphea


This study aimed to describe the demographical and clinical characteristics of a retrospective cohort of adult-onset GM and to investigate whether these findings differ between patients with an isomorphic and a symmetric pattern of lesion distribution.

Full Title of Study: “Adult-onset Generalized Morphea : A Retrospective Multicenter Study”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: April 2020

Clinical Trial Outcome Measures

Primary Measures

  • Retrospective study of generalized morphea in adult patients consulted in dermatology departments
    • Time Frame: Files analyzed retrospectily from January 1st, 2019 to September 30, 2019 will be examined

Participating in This Clinical Trial

Inclusion Criteria

  • Age of onset ≥ 18 years – Patients with generalized morphea as defined by criteria established by Laxer and Zulian (4 or more morpheaform plaques larger than 3 centimeters that show tendency to confluence and involve at least 2 different anatomic sites) – Availability of good-quality clinical photographs – Patient who, after being informed, has not expressed his or her opposition to the re-use of his or her data for the purposes of this research Exclusion Criteria:

  • Patients with linear morphea who met criteria for generalized morphea – Patient's opposition to participate

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Investigator Details

  • Lead Sponsor
    • University Hospital, Strasbourg, France
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Cédric LENORMAND, MD, Study Director, University Hospital, Strasbourg, France
  • Overall Contact(s)
    • Cédric LENORMAND, MD, 33 3 88 11 66 27,

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