Rabies Treatment by Exposure of Patient to X-Ray

Overview

x-ray has been proven to kill Rabies virus in vitro, so the investigators can use it in treatment of rabies infected patients.

Full Title of Study: “Effect of X-ray on Rabies Virus in Vivo”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Non-Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: Double (Participant, Investigator)
  • Study Primary Completion Date: July 2020

Detailed Description

x-ray has been proven to kill Rabies virus in vitro, so the investigators can use it in treatment of rabies infected patients. this can be done by exposure of infected , manifested patient who didn't receive prophylaxis or delayed in receiving immunoglobulins . also can be applied to patients who have the injury in upper body near the CNS.. it's just an idea and the investigators need help to approve its effect and the investigators believe it will really work and give a new, rapid , cheap and very effective treatment to a 100% fatal disease.. the investigator also predict good results when x ray applied to some localized infections beside its current lines of treatment..

Interventions

  • Radiation: x ray exposure
    • exposure of whole body to x ray

Arms, Groups and Cohorts

  • Experimental: rabies patient 1
    • not received immunoglobulins and symptomatic
  • Experimental: rabies patient 2
    • received immunoglobulins and symptomatic
  • Experimental: rabies patient 3
    • not received immunoglobulins and not yet symptomatic
  • Experimental: rabies patient 4
    • received immunoglobulins and not symptomatic

Clinical Trial Outcome Measures

Primary Measures

  • the number of rabies infected, symptomatic patients who survived after x-ray exposure
    • Time Frame: 7 month
    • detecting effect of x-ray exposure on treating Rabies

Participating in This Clinical Trial

Inclusion Criteria

  • patient bitten by rabid animal with signs and symptoms Exclusion Criteria:

  • bitten by non rabid animal

Gender Eligibility: All

Minimum Age: N/A

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • National Institute For Research On Endemic Diseases And Liver, Egypt
  • Provider of Information About this Clinical Study
    • Principal Investigator: Ahmed Samir Mohammed El Behwashy, Principal Investigator – National Institute For Research On Endemic Diseases And Liver, Egypt
  • Overall Contact(s)
    • Ahmed Samir El-Behwashy, fellowship, 01001814806, ahmedelsamir@gmail.com

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