Analysis of Biomarkers in Lymph Node Tissue


Researchers are doing an exploratory analysis of biomarkers to correlate with treatment outcome of transplant surgery.

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: January 6, 2022

Detailed Description

Researchers will study previously collected tissue, which was sent for pathological examination, of 200 patients who underwent transplant surgery. Concentration of biomarkers in lymph node tissue will be measured.

Clinical Trial Outcome Measures

Primary Measures

  • List of biomarkers
    • Time Frame: Baseline
    • Immunohistochemistry (IHC) for the LYVE1, VEGFR3 expression, VEGF-A/C/D, Ki-67, MMP-9 and TIMP-1

Participating in This Clinical Trial

Inclusion Criteria

  • Adults (18+years of age)
  • Undergo any organ transplant

Exclusion Criteria

  • Under the age of 18 years old

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Mayo Clinic
  • Provider of Information About this Clinical Study
    • Principal Investigator: Antonio J. Forte, Principal Investigator – Mayo Clinic
  • Overall Official(s)
    • Antonio Forte, MD, PhD, Principal Investigator, Mayo Clinic

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