Protocol of Management of Major Pediatric Burn in Intensive Care Unit

Overview

Decrease mortality and morbidity in major pediatric burns

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: N/A
    • Intervention Model: Single Group Assignment
    • Primary Purpose: Treatment
    • Masking: None (Open Label)
  • Study Primary Completion Date: June 2021

Detailed Description

The goals of initial patient management include preservation of overall homeostasis while appreciating the physiologic challenges that the burn injury poses to the body. Major burn injury not only results in local damage from the inciting injury, but in many cases results in multisystem injury. Initial efforts are focused on resuscitation, maintaining hemodynamic stability, and airway management. Intermediate efforts are focused on managing the multi-organ failure that results from systemic inflammatory mediators that result in diffuse capillary leak and surgical therapy. Finally, efforts shift to issues with chronic wound healing, pain management, restoration of functional capabilities, and rehabilitation.. Burn injury in children continues to be a major epidemiologic problem around the globe. Nearly a fourth of all burn injuries occur in children under the age of 16, of whom the majority are under the age of five This provides a team of pediatricians, surgeons, anesthesiologists, intensivists, nurses, respiratory therapists, and other healthcare providers with a unique opportunity to make a multidisciplinary collaborative effort.

Interventions

  • Other: protocol of management of major burn in intensive care unit
    • primary assessment first aid management laboratory investigation radiological investigation surgical intervention

Arms, Groups and Cohorts

  • Experimental: intensive care management
    • Administration of childern with major burn in intensive care to improve out comes

Clinical Trial Outcome Measures

Primary Measures

  • Changing mortality rate
    • Time Frame: baseline
    • Change mortality rate to lowest degree which due too severe burn less than 20% of childern with major burn

Secondary Measures

  • Changing hospital stay time
    • Time Frame: Baseline
    • Hospital stay less than 30 days

Participating in This Clinical Trial

Inclusion Criteria

  • age below 18 year – children with burn between 20% to 50% of total body surface area – recent burn within 48 hour Exclusion Criteria:

  • old burn over 48 hour after injury -burnt surface area less than 20% of total body surface area – - – burnt surface area more than 50% of total body surface area – old age over 18 year

Gender Eligibility: All

Minimum Age: 1 Year

Maximum Age: 18 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Assiut University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Mohamed elsayed tawfik, Official investigator – Assiut University
  • Overall Official(s)
    • Azza Eltayeb, Professor, Study Director, Professor
  • Overall Contact(s)
    • Mohamed elsayed, doctor, 01029980167, mohamed011349@med.au.edu.eg

References

Krishnamoorthy V, Ramaiah R, Bhananker SM. Pediatric burn injuries. Int J Crit Illn Inj Sci. 2012 Sep;2(3):128-34. doi: 10.4103/2229-5151.100889.

Williams FN, Herndon DN, Hawkins HK, Lee JO, Cox RA, Kulp GA, Finnerty CC, Chinkes DL, Jeschke MG. The leading causes of death after burn injury in a single pediatric burn center. Crit Care. 2009;13(6):R183. doi: 10.1186/cc8170. Epub 2009 Nov 17.

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