Early Lactate Clearance Rate in Sepsis


To assess the Influence of early lactate clearance rate monitoring in patients with sepsis.

Full Title of Study: “Monitoring and Guidance of Early Lactate Clearance Rate in Patients With Sepsis”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: January 31, 2020


  • Diagnostic Test: lactate clearance
    • Lactate clearance rate was monitored within 6 hours after admission

Arms, Groups and Cohorts

  • lactate group
    • Lactate early guide resuscitation
  • control group
    • early guide resuscitation without lactate

Clinical Trial Outcome Measures

Primary Measures

  • In-hospital 60days mortality
    • Time Frame: In-hospital 60 days
    • In-hospital up to 60 days mortality of sepsis
  • ICU mortality
    • Time Frame: up to 30 days
    • ICU up to 30 days mortality of sepsis

Participating in This Clinical Trial

Inclusion Criteria

  • All patients whose blood lactate level reached or exceeded 2.0 mEq / L Exclusion Criteria:

  • Incomplete clinical data

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • The Second Hospital of Hebei Medical University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Fei Tong, Director – The Second Hospital of Hebei Medical University
  • Overall Contact(s)
    • Fei Tong, Dr., +8615803210603, tongfei168@163.com

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