Therapeutic Literacy Evaluation in Liver Transplanted Patients


Health literacy is a new concept in therapeutic patient education. Health Literacy has been defined as the cognitive and social skills which determine the motivation and ability of individuals to gain access to, understand and use information in ways which promote and maintain good health. Health literacy seems predictive of adherence 's patients to treatment or positive health behavior.

Liver transplanted patients need to modify their lifestyle and to perform new behaviors in order to improve their survival and their quality of life. Health literacy evaluation in these patients is necessary to know what they understand and to improve their intake.

The Aim of the study is to evaluate health literacy among liver transplanted patient and to perform liver transplanted patient profiles related to their own health literacy.

The second aim is to study the impact of health literacy on medication adherence and iatrogenic hospitalizations It is a monocentric non-randomized study. During the hepatologist consultation, the HLQ Health Literacy Questionnaire is performed to explore patient health understanding and perception. Then the pharmacist interviews the patient to explore motivations and brakes for their own healthcare; Furthermore, a cognitive and precarity evaluation is performed in order to analyze psychological or social factors which can influence health literacy.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: N/A
    • Intervention Model: Single Group Assignment
    • Primary Purpose: Supportive Care
    • Masking: None (Open Label)
  • Study Primary Completion Date: December 2019

Detailed Description

Tests performed:

- Health Literacy Questionnaire: HLQ

- Montreal Cognitive Evaluation Assessment: MoCA

- EPICES: precarity test validated in French

- A qualitative interview


  • Other: HLQ (Health literacy questionnaire)
    • each patient complete survey and self-assessment questionnaire before or after his medical consultation
  • Other: MoCA (Montreal Cognitive Assessment)
    • each patient complete survey and self-assessment questionnaire before or after his medical consultation

Arms, Groups and Cohorts

  • Experimental: Cohort 1
    • liver transplanted patient

Clinical Trial Outcome Measures

Primary Measures

  • health literacy questionnaire
    • Time Frame: day 1
    • a survey in 2 parts. Each part contains about twenty questions with Likert scale

Secondary Measures

  • MoCA questionnaire
    • Time Frame: day 1
    • evaluation of cognitive assessment and detection mild cognitive dysfunction at the consultation
  • EPICES questionnaire
    • Time Frame: day 1
    • auto-evaluation of social and economic status

Participating in This Clinical Trial

Inclusion Criteria

  • Adult patient > 18 years
  • Liver transplanted patient > 1 year at the start of the study
  • patient who are followed-up by an hepatologist in the center
  • patient who understands and speaks French

Exclusion Criteria

  • patient not yet liver transplanted (on the waiting-list)
  • patient who has not come back home yet
  • patient who does not speak or understand French
  • patient refusal to participate
  • patient under supervision or guardianship

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • University Hospital, Clermont-Ferrand
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Sarah Talavera, Principal Investigator, University Hospital, Clermont-Ferrand
  • Overall Contact(s)
    • Lise Laclautre, 334.73.754.963,

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