Ophthalmic Artery Resistance Index After Peribulbar Block in the Presence of Epinephrine

Overview

Evaluate ophthalmic artery flow by echo-Doppler before and after peribulbar block with lidocaine in presence or absence of epinephrine.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Prevention
    • Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
  • Study Primary Completion Date: May 31, 2014

Detailed Description

There are controversies regarding the ophthalmic artery (OA) flow after peribulbar block with the addition of epinephrine. Therefore, we aimed to evaluate OA flow by echo-Doppler before and after peribulbar block with lidocaine in presence or absence of epinephrine. Fifty-six patients that were eligible for cataract phacoemulsification surgery were selected. Patients were divided into two groups: group 1 – Peribulbar block with lidocaine and 1/200.000 epinephrine; group 2 – Peribulbar block with lidocaine in the absence of epinephrine. The resistance index (RI) of OA was evaluated using echo-Doppler before and 10 min after the peribulbar block.

Interventions

  • Drug: Epinephrine

Arms, Groups and Cohorts

  • Experimental: Lidocaine with epinephrine
    • Peribulbar anesthesia with lidocaine and epinephrine
  • No Intervention: Lidocaine without epinephrine
    • Peribulbar anesthesia with lidocaine

Clinical Trial Outcome Measures

Primary Measures

  • Artery resistance index of ophthalmic artery
    • Time Frame: Change on resistance index 10 minutes after peribulbar anesthesia
    • The resistance index (RI) of OA was evaluated using echo-Doppler before and 10 minutes after the peribulbar block.

Participating in This Clinical Trial

Inclusion Criteria

  • American Society of Anesthesiologists (ASA) I, II or III physical status classification – Cataract surgery Exclusion Criteria:

  • glaucoma – diabetic retinopathy – previous eye surgery in the same eye – ocular trauma – allergic to any protocol medication – uncooperative patients or cognitive difficulties – axial eye diameter of less than 21.0 mm or greater than 25.5 mm.

Gender Eligibility: All

Minimum Age: 30 Years

Maximum Age: 85 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Federal University of Minas Gerais
  • Provider of Information About this Clinical Study
    • Principal Investigator: Renato Santiago Gomez, Professor – Federal University of Minas Gerais

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