Effects of Motor Imagery in Pain Modulation and Median Nerve Mechanosensitive in Healthy Patients


The aim of this study are 1) to determinate the effectiveness of motor imagery or strength training in differens aspects of pain modulation. 2) evaluate the functional improvement of the hand by a motor imagery protocol.

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: Single (Investigator)
  • Study Primary Completion Date: January 31, 2020


  • Other: Action observation
    • look at a clip of a hand doing neurodynamic exercises.
  • Other: Mirror therapy
    • With a mirror glasses on, do the neurodynamic exercises with the non-dominant hand while the patient is looking at the dominant hand
  • Other: Neurodynamic exercises
    • active movement of the dominant hand. Do neurodynamic exercises.
  • Other: Strength
    • Execute a short strength training for the dominant hand

Arms, Groups and Cohorts

  • Experimental: Action observation
    • The patients will observe a 25 minutes clip of neurodynamic exercises of the hand.
  • Experimental: Mirror Therapy
    • With a mirror glasses, the patients will execute neurodynamic movements of their non-dominant hand during 25 minutes.
  • Active Comparator: Strength Training
    • Strength protocol for the dominant hand.
  • Experimental: Neurodynamic exercise
    • Active neurodynamic exercises for the dominant hand.

Clinical Trial Outcome Measures

Primary Measures

  • Conditioned pain modulation
    • Time Frame: Change from baseline at 2 weeks
    • Diffused noxious inhibitory control system will be measure with tourniquet test
  • Pressure pain threshold
    • Time Frame: Change from baseline at 2 weeks
    • Three consecutive trials of pressure pain threshold on the active trigger point at a rate of 1 kg/sec at intervals of 30 seconds were conducted.
  • Cold hyperalgesia
    • Time Frame: Change from baseline at 2 weeks
    • 10 seconds of a cold pack and after that, rating the pain from 0 to 10
  • Neural mechanosensitive
    • Time Frame: Change from baseline at 2 weeks
    • Upper Limb Neurodynamic test 1 (ULNT1)

Secondary Measures

  • Strength_grip
    • Time Frame: Change from baseline at 2 weeks
    • grip strength without pain
  • Imagine movement capacity
    • Time Frame: Change from baseline at 2 weeks
    • testing the capacity of imagine that their own body is movement. Movement Imagery Questionnaire-Revised (MIQ-R questionaire). top score 56 and bottom score 8. The higher values indicates a better outcome.
  • Psychological factors_Anxiety
    • Time Frame: Change from baseline at 2 weeks
    • State Trait Anxiety Inventory (STAI-T). Top score 60 and bottom score 0. The higher values indicate worst outcomes.
  • Psychological factors_Depression
    • Time Frame: Change from baseline at 2 weeks
    • Beck Depression Inventory (BDI-II). the scores goes from 0 to 63. The higher values indicate worst outcomes. Beck Depression Inventory (BDI-II) Beck Depression Inventory (BDI-II)
  • Psychological factors_Kinesiophobia
    • Time Frame: Change from baseline at 2 weeks
    • Tampa Scale for Kinesiophobia. Total scores goes from 11 to 44.The higher values indicate worst outcomes.

Participating in This Clinical Trial

Inclusion Criteria

  • Healthy

Exclusion Criteria

  • be under 18
  • any pathology which provoke pain.

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 65 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Universidad Rey Juan Carlos
  • Provider of Information About this Clinical Study
    • Principal Investigator: Josue Fernandez Carnero, Principal Investigator – Universidad Rey Juan Carlos
  • Overall Contact(s)
    • Josue Fernandez, PhD, 34914888949, josue.fernandez@urjc.es

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