Ileus After Lumbar Spine Surgery

Overview

Postoperative ileus (POI) after lumbar spine surgery is not uncommon. However, the incidence, severity and risk factors of ileus after spine surgery remain uncertain because there is not yet a prospective investigation using a subjective grading evaluation tool.

Full Title of Study: “Investigation of Postoperative Ileus After Lumbar Spine Surgery: a Prospective Observational Study”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: July 2022

Detailed Description

This study aims to prospectively investigate the incidence of POI after spine surgery by using two subjective grading systems, namely AGI grade as well as IFEED scoring system. The severity of POI after spine surgery thus could be stratified and then an investigation of possible risk factors could be identified. In addition, we will also investigate potential serum relevant biomarkers such as fatty acid-binding protein (i-FABP) , D-lactate (D-la), and lipopolysaccharide.

Clinical Trial Outcome Measures

Primary Measures

  • Severity of POI
    • Time Frame: 2-7 days
    • POI severity gauged by AGI grading system and IFEED scoring system.

Secondary Measures

  • Serum gastrointestinal biomarkers
    • Time Frame: 1-6 hours
    • Intraoperative changes in serum fatty acid-binding protein (i-FABP) , D-lactate (D-la), and lipopolysaccharide levels

Participating in This Clinical Trial

Adult patients who undergoing elective lumbar spine surgery

Gender Eligibility: All

Minimum Age: 20 Years

Maximum Age: 90 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • National Taiwan University Hospital
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Fon-Yih Tsuang, MD, Principal Investigator, National Taiwan University Hospital
  • Overall Contact(s)
    • Fon-Yih Tsuang, 886972651142, tsuangfy@gmail.com

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.