Fall Prevention in Elderly: Mechanisms and Strategies

Overview

In communities with over 100,000 residents, to investigate the incidence and mechanisms of fall in elderly, and strategies of fall prevention.

Full Title of Study: “STrategies and mechAnisms of Community-Based falL Prevention in Elderly”

Study Type

• Study Type: Interventional
• Study Design
  • Allocation: Non-Randomized
  • Intervention Model: Factorial Assignment
  • Primary Purpose: Diagnostic
  • Masking: None (Open Label)
• Study Primary Completion Date: December 31, 2022

Interventions

• Behavioral: Exercise
  • Elderly people with or without fall history receive exercise to improve balance. Exercise interevention will be given 6 months in 2020. Outcomes (incidence of fall and biological tests) between two arms will be compared.

Arms, Groups and Cohorts

• Other: Elderly without fall history
  • Elderly people in the community who have no fall history
• Other: Elderly with fall history
  • Elderly people in the community who have fall history

Clinical Trial Outcome Measures

Primary Measures

• Incidence of fall
  • Time Frame: From date of recruitment until the end of the study, assessed up to 42 months (reported once per year)
  • Incidence of fall each year

Secondary Measures

• Kinematics test
  • Time Frame: From date of recruitment until the end of the study, assessed up to 42 months
  • During balance tests, assessing kinematics by using inertia sensors.
• Kinetics test
  • Time Frame: From date of recruitment until the end of the study, assessed up to 42 months
  • During balance tests, assessing kinetics by using sEMG (high-density surface EMG).
• EEG test
  • Time Frame: From date of recruitment until the end of the study, assessed up to 42 months
  • During balance tests, assessing brain mechanisms by using electroencephalogram (EEG).
• fNIRS test
  • Time Frame: From date of recruitment until the end of the study, assessed up to 42 months
  • During balance tests, assessing brain mechanisms by using functional near-infrared spectroscopy (fNIRS).
• MRI assessments
  • Time Frame: From date of recruitment until the end of the study, assessed up to 42 months
  • Using functional magnetic resonance imaging to assess brain mechanisms during foot movements.

Participating in This Clinical Trial

Inclusion Criteria

• community dwelling adults without medical conditions to impair walking ability Exclusion Criteria:

• cognitively or physically unable to cooperate with the examiner to finish the test

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: 85 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

• Lead Sponsor
  • National Research Center for Rehabilitation Technical Aids
• Collaborator
  • Ministry of Science and Technology of the People´s Republic of China
• Provider of Information About this Clinical Study
  • Principal Investigator: Pengxu Wei, Director – National Research Center for Rehabilitation Technical Aids
• Overall Contact(s)
  • HL Su, Dr, 86-10-58122882, suhonglun@nrcrta.cn