Clinical Impact of the FilmArray Blood Culture Identification Panel Performed on Positive Blood Cultures From Intensive Care Patients With Septicemia

Overview

Molecular testing is a largely validated approach allowing rapid identification of positive blood cultures. However, due to its high cost and its limited information on susceptibility, it is considered as an add-on technique reserved for specific patient populations. In our study, we specifically evaluated molecular testing in a critical care setting and measured its impact on the therapeutic management of critically ill with positive blood cultures. Through the analysis of 110 positive blood culture episodes included in both pre- and post intervention period, we measured a drastic 14h-reduction of the time to administration of the optimal antimicrobial treatment with the use of the molecular approach.

Full Title of Study: “The Impact of a Rapid Molecular Identification Test on Positive Blood Cultures From Critically Ill With Bacteremia: a Pre-post Intervention Study”

Study Type

  • Study Type: Observational [Patient Registry]
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: December 31, 2017

Interventions

  • Diagnostic Test: FilmArray blood culture identification panel
    • FilmArray blood culture identification panel is performed 24 hours on 24hours and 7 days a week on positive blood cultures to accelerate pathogens detection

Clinical Trial Outcome Measures

Primary Measures

  • Turn Around Time to optimal treatment of septicemia
    • Time Frame: From positivity detection of positive blood culture to administration of optimal treatment (up to 48 hours)
    • Time in minutes

Participating in This Clinical Trial

Inclusion Criteria

  • adult intensive care unit patients with positive blood cultures Exclusion Criteria:

  • palliative care patients

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Investigator Details

  • Lead Sponsor
    • Cliniques universitaires Saint-Luc- Université Catholique de Louvain
  • Collaborator
    • BioMérieux
  • Provider of Information About this Clinical Study
    • Sponsor
  • Overall Official(s)
    • Alexia VERROKEN, Principal Investigator, Cliniques universitaires St-Luc

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.