Infrapyloric and Greater Curvature Lymph Node Metastasis in Colon Cancer

Overview

The infrapyloric (No.206) and greater curvature (No.204) lymph node metastasis in adenocarcinoma located at hepatic flexure and right half of transverse colon has not been well discribed and analysed. The aim of this study is to assess the rate of this lymph node metastasis and to reveal its prognostic value for colon cancer located at hepatic flexure and right half of transverse colon. Meanwhile, we can evaluate the safety and feasibility of this extented lymphadenectomy in right hemi-colectomy.

Full Title of Study: “Infrapyloric (No.206) and Greater Curvature (No.204) Lymph Node Metastasis in Adenocarcinoma Located at Hepatic Flexure and Right Half of Transverse Colon”

Study Type

  • Study Type: Observational [Patient Registry]
  • Study Design
    • Time Perspective: Prospective
  • Study Primary Completion Date: August 2020

Clinical Trial Outcome Measures

Primary Measures

  • metastasis rate
    • Time Frame: an average of 1 year
    • metastasis rate of infrapyloric (No.206) and greater curvature (No.204) lymph node

Secondary Measures

  • lymphadenectomy time
    • Time Frame: an average of 1 year
    • time of lymphadenectomy of infrapyloric (No.206) and greater curvature (No.204) lymph node
  • intraoperative complication
    • Time Frame: an average of 1 year
    • intraoperative complication
  • postoperative complication
    • Time Frame: an average of 1 year
    • postoperative complication
  • 3-year DFS
    • Time Frame: an average of 3 years
    • 3-year disease free survival

Participating in This Clinical Trial

Inclusion Criteria

  • Age between 18 and 75 years – American Society of Anesthesiologists (ASA) score I to III – A biopsy proven histological diagnosis of colorectal carcinoma – tumor located at hepatic flexure and right half of transverse colon – Undergoing right hemi-colectomy with extented lymphadenectomy of infrapyloric (No.206) and greater curvature (No.204) lymph node – Preoperative staging cT2-4aN0M0 or cTanyN+M0 – Willing to participate and informed consent signed Exclusion Criteria:
  • Pregnant or lactating women – Synchronous colorectal carcinoma – History of colorectal cancer or other malignant tumors – Clinical evidence of metastasis – Preoperative staging cT1N0 or cT4bNany – Emergency procedure
  • Gender Eligibility: All

    Minimum Age: 18 Years

    Maximum Age: 75 Years

    Are Healthy Volunteers Accepted: No

    Investigator Details

    • Lead Sponsor
      • Shanghai Minimally Invasive Surgery Center
    • Provider of Information About this Clinical Study
      • Sponsor
    • Overall Contact(s)
      • Zhenghao CAI, MD, +862164458887, c3z2h1@alumni.sjtu.edu.cn

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