Mebendazole as Adjuvant Treatment for Colon Cancer

Overview

mebendazole treating colon cancer

Full Title of Study: “Clinical Study Evaluating Mebendazole as Adjuvant Therapy in Patients With Colorectal Cancer”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: None (Open Label)
  • Study Primary Completion Date: December 2028

Detailed Description

mebendazole as adjuvant treatment for colon cancer

Interventions

  • Drug: Folfox with avastin
    • Folfox with avastin only
  • Drug: Mebendazole
    • Folfox with avastin with mebendazole

Arms, Groups and Cohorts

  • Active Comparator: Folfox with avastin
    • Folfox with avastin only
  • Experimental: Mebendazole
    • Folfox with avastin with mebendazole

Clinical Trial Outcome Measures

Primary Measures

  • number of patients with tumour response
    • Time Frame: 6 months
    • number of patients with response

Participating in This Clinical Trial

Inclusion Criteria

  • Colorectal cancer stage 4. Exclusion Criteria:

  • Agranulocytosis – Pregnancy – Allergy to mebendazole.

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Sherief Abd-Elsalam
  • Provider of Information About this Clinical Study
    • Sponsor-Investigator: Sherief Abd-Elsalam, Ass. Prof. Tropical Medicine – Tanta University
  • Overall Official(s)
    • Reham El-ghoneimy, Msc, Principal Investigator, Tanta University – Faculty of Pharmacy
    • Sahar Hegazy, Prof, Principal Investigator, Tanta University – Faculty of Pharmacy
    • Gamal el-azab, Prof, Study Director, Tanta University – Faculty of Pharmacy
    • Fatma Zakaria, Prof, Study Chair, Clinical Oncology department. Tanta University.
  • Overall Contact(s)
    • Sherief Abd-Elsalam, ass. prof., 00201147773440, sheriefabdelsalam@yahoo.com

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