Predictive Factors of Inadequate Bowel Preparation in Inpatients

Overview

About 50-70% only of inpatients who undergo colonoscopy have an adequate bowel cleansing, which is far below the recommended threshold of 90%. Variables associated to inadequate colon preparation have not been assessed yet. Identifying such variables would allow to augment the diagnostic yield of colonoscopy, and also to reduce costs related to the need to repeat colonoscopy. Aim of the present study is to find variables independently associated to an inadequate bowel cleansing and to subsequently build and validate a predictive model, which could prove useful in clinical practice to identify hard-to-prepare inpatients. Secondary endpoints are (i) to assess the proportion of patients with inadequate colon cleansing, (ii) to run a cost-effectiveness analysis between patients with adequate cleansing and patients who need to repeat colonoscopy. Patients undergoing urgent colonoscopy, and patients who take the preparation at home will be excluded.

Full Title of Study: “Identification of Predictive Factors of Inadequate Bowel Preparation in Inpatients. The Quality-In-Patients Study (QIPS)”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Cross-Sectional
  • Study Primary Completion Date: August 31, 2019

Clinical Trial Outcome Measures

Primary Measures

  • Inadequate bowel cleansing rate
    • Time Frame: At the end of the study, 3 months after the beginning of the study.
    • The number of inpatients with inadequate bowel preparation over the total number of patients enrolled. Bowel prep will be assessed according to the Boston Bowel Preparation Scale (BBPS). A score less than 2 at one segment of the colon will be considered as inadequate bowel preparation.

Secondary Measures

  • Rate of patients scheduled for colonoscopy repetition due to inadequate bowel preparation
    • Time Frame: At the end of the study, 3 months after the beginning of the study.
    • Total number of patients scheduled for repeating colonoscopy over the total number of patients enrolled scheduled for repeating colonoscopy due to poor bowel pre.

Participating in This Clinical Trial

Inclusion Criteria

  • Inpatient ≥18 y.o. who are scheduled elective colonoscopy during hospitalization irrespective of the indication. Exclusion Criteria:

  • Urgent colonoscopy – Patients who are not hospitalized when taking bowel preparation or when undergoing colonoscopy

Gender Eligibility: All

Minimum Age: 18 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • IRCCS Azienda Ospedaliero-Universitaria di Bologna
  • Provider of Information About this Clinical Study
    • Principal Investigator: Lorenzo Fuccio, Professor of Gastroenterology – IRCCS Azienda Ospedaliero-Universitaria di Bologna

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