Outcome Evaluation for Burn Scar Therapy-laser and Surgery in Patients in Formosa Fun Coast Explosion

Overview

Protocol title: Outcome evaluation for burn scar therapy-laser and surgery in patients in Formosa Fun Coast Explosion Objectives: The goal of this study is to evaluate the effectiveness of both lasers and operations on patients with major burn scar(>20% TBSA).

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: N/A
    • Intervention Model: Single Group Assignment
    • Primary Purpose: Health Services Research
    • Masking: None (Open Label)
  • Study Primary Completion Date: January 27, 2019

Detailed Description

Background: There is no gold standard treatment for burn scar treatment, especially for those with major burn scar. In the Formosa Fun-Coast Dust Explosion in 2015, lots of patients with major burn scar suffer from severe pathologic burn scar syndromes. The gold of the study is to evaluate the efficacy of both lasers and operations on major burn scars treatment in the past two years. Study Design: To take the assessment of scar into account, the investigators use both objectives and subjective methods to evaluate the scar condition. In addition to the scale of scar, the investigators also use both sonography and HRV system to evaluate the expressions of scar. All evaluated tools used are the same as those used in 20160201R and 20160202R. The investigators also used previous records to check the patient's scar condition before these treatments. Hypothesis: After treatment, scar conditions should get better than before. However, the investigators need more scientific statistics to evaluate the improve rate. Key words: Burn scar, burn scar syndromes. Scar laser treatment

Interventions

  • Procedure: Laser and Surgery
    • Laser and Surgery in patients with major burn scars Evaluating after three years treatment

Arms, Groups and Cohorts

  • Other: Laser and Surgery in patients with major burn scars
    • Evaluating patients with major burn scar after laser and surgical treatments Multiple-directions evaluation, including senior plastic resident, young resident, professional burn surgeons, senior nurse with burn scar, one non-medical patients(usually patients’ family and friends)

Clinical Trial Outcome Measures

Primary Measures

  • Patients objective questionnaire
    • Time Frame: Week 0
    • Patients objective questionnaires is used to evaluate subjects’ sensation and life quality, in which pain, itchiness and sleep are evaluated by Visual Analogue Scale (VAS), Burn Itchiness Scale and Sleep Assessment Scale, respectively.
  • Burn assessment by researchers
    • Time Frame: Week 0
    • Burn scars are assessed using Vancouver scar scale by four plastic surgeons and a non-professional person.

Secondary Measures

  • Scar evaluation by sonography (selective)
    • Time Frame: Week 0
    • Burn scars in lower extremity are measured using 2-D problem sonography machine.
  • Autonomic nervous system analysis (selective)
    • Time Frame: Week 0
    • Autonomic nervous system analysis is performed by heart-rate variability machine (HRV MACHINE).

Participating in This Clinical Trial

Inclusion Criteria

1. >20% major burn scar, for 3 years 2. patients in Formosa FunCost Explosion 3. offering medical records, including laser and treatments 4. available for questionnaire evaluation and others' evaluation 5. those are willing to receive both sonography on scars and HRV evaluation Exclusion Criteria:

1. those aren't willing to offer medical records 2. those aren't willing to fill questionnaire 3. those aren't willing to receive sonography on scars

Gender Eligibility: All

Minimum Age: 20 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Shin Kong Wu Ho-Su Memorial Hospital
  • Provider of Information About this Clinical Study
    • Principal Investigator: CHACHUN, CHEN, Plastic Surgeon – Shin Kong Wu Ho-Su Memorial Hospital

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