Mat Pilates and Vascular Function in Obese Females

Overview

Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as exercise training. We examined the effects of a Mat Pilates training (MPT) regimen on arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), wave reflection (AIx) and endothelial function in obese premenopausal women with elevated BP.

Full Title of Study: “The Effects of Mat Pilates Training on Vascular Function in Obese Premenopausal Women With Elevated Blood Pressure”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Treatment
    • Masking: Single (Outcomes Assessor)
  • Study Primary Completion Date: October 30, 2018

Detailed Description

Using a parallel experimental design, participants were randomly assigned to either MPT (n=14) or non-exercising control group (n=14) for 12 weeks. Participant in the MPT group trained 3 days/week . Participants' brachial to ankle PWV (baPWV), systolic and diastolic BP, AIx, plasma NO levels were measured at baseline and after 20 weeks of their assigned intervention.

Interventions

  • Behavioral: Mat Pilates training
    • This group completed 12-weeks of training

Arms, Groups and Cohorts

  • Experimental: Mat Pilates training
    • The MPT group participated in 3-one hour supervised training sessions per week for 12 weeks. All MP sessions were performed in nonconsecutive days. The MP sessions were divided into the following stages: initial warm up and stretching (10 min), general conditioning consisting of MP exercises (40 min) and stretching and cooling down (10 min). The participants performed 12 basic MP exercises (one set of 6-10 repetitions was performed per exercise). Breathing, a core principle of MP, was performed by forced but controlled inspirations and exhalations, while relaxing and contracting the abdomen, respectively. All sessions were supervised by a certified MP instructor.
  • No Intervention: Control
    • Participants in the non-exercising control group did not participate in a supervised exercise program and visited the laboratory at the same frequency as participants in the swim intervention and underwent recreational activities such as board games

Clinical Trial Outcome Measures

Primary Measures

  • Arterial Stiffness
    • Time Frame: 12 weeks
    • via Pulse Wave Velocity

Secondary Measures

  • Systolic and Diastolic Blood Pressure
    • Time Frame: 12 weeks
    • Automatic BP monitor
  • Pressure Wave Reflection
    • Time Frame: 12 weeks
    • via Augmentation Index
  • Endothelial Function
    • Time Frame: 12 weeks
    • via plasma nitric oxide

Participating in This Clinical Trial

Inclusion Criteria

  • body mass index 30-40 kg/m2 – <1 h of regular exercise per week in the previous year – systolic/diastolic BP: 120-129mm Hg systolic BP and ˂ 80 mm Hg for diastolic BP – Nonsmokers Exclusion Criteria:

  • body mass index ˂30 and ≥40 kg/m2 – chronic diseases – taking oral contraceptives – pregnancy

Gender Eligibility: Female

Minimum Age: 18 Years

Maximum Age: 35 Years

Are Healthy Volunteers Accepted: Accepts Healthy Volunteers

Investigator Details

  • Lead Sponsor
    • Marymount University
  • Collaborator
    • Busan University
  • Provider of Information About this Clinical Study
    • Principal Investigator: Alexei Wong, Assistant Professor – Marymount University

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