Oxytocin Infusion and Abdominal Myomectomy

Overview

Objective:To compare oxytocin infusion with control, in patients undergoing abdominal myomectomy in terms of mean blood loss.

Design: Single blinded randomized control trial Setting: Obstetrics and Gynecology Department, Military Hospital, Rawalpindi Population: 60 women of ASA class I-II, with intramural fibroids, candidate for elective abdominal myomectomy.

Methods: Women were divided into two groups randomly. In the study group 30 Units of oxytocin in 1000 ml normal saline were given during surgery, at the rate of 15units/hour. In control group, pure normal saline was given.

Main outcome measure: Intra-operative blood loss

Full Title of Study: “Effect of Oxytocin Infusion on Reducing the Blood Loss During Abdominal Myomectomy: A Randomized Controlled Trial”

Study Type

  • Study Type: Interventional
  • Study Design
    • Allocation: Randomized
    • Intervention Model: Parallel Assignment
    • Primary Purpose: Prevention
    • Masking: Single (Participant)
  • Study Primary Completion Date: January 15, 2018

Interventions

  • Other: oxytocin in abdominal myomectomy
    • Women were divided into two groups randomly. In the study group 30 Units of oxytocin in 1000 ml normal saline were given during surgery, at the rate of 15units/hour. In control group, pure normal saline was given

Arms, Groups and Cohorts

  • Experimental: study group
  • No Intervention: control group

Clinical Trial Outcome Measures

Primary Measures

  • Intra-operative blood loss
    • Time Frame: during the surgical procedure
    • average intra operative blood loss was measured

Participating in This Clinical Trial

Inclusion Criteria

1. women of ASA class I-II with intramural fibroids,

2. women planned to undergo elective abdominal myomectomy

Exclusion Criteria

1. Women with hemoglobin (Hb) < 10g/dl

2. Women with any respiratory or cardiovascular disease.

Gender Eligibility: Female

Minimum Age: 25 Years

Maximum Age: 40 Years

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • Armed Forces Hospital, Pakistan
  • Provider of Information About this Clinical Study
    • Principal Investigator: arshad khushdil, Assistant professor – Armed Forces Hospital, Pakistan

Clinical trials entries are delivered from the US National Institutes of Health and are not reviewed separately by this site. Please see the identifier information above for retrieving further details from the government database.

At TrialBulletin.com, we keep tabs on over 200,000 clinical trials in the US and abroad, using medical data supplied directly by the US National Institutes of Health. Please see the About and Contact page for details.