Effects of Resistin on Neutrophil Function
Overview
To assess the effect of resistin on neutrophil migration and intracellular bacterial killing
Study Type
- Study Type: Observational
- Study Design
- Time Perspective: Prospective
- Study Primary Completion Date: September 1, 2019
Clinical Trial Outcome Measures
Primary Measures
- intracellular bacterial killing, assessed by number of colonies of bacterial growth following neutrophil exposure to bacteria and resistin
- Time Frame: 6 months
Participating in This Clinical Trial
Inclusion Criteria
- age ≥ 18 – gender: male or female Exclusion Criteria – Adults who are unable to provide informed consent themselves – History of chronic kidney disease as defined by estimated glomerular filtration rate (GFR) <60 ml/min prior to cardiogenic shock – Patients with hematologic malignancies – Pregnant women – Patient/surrogate is not fluent in English – Long-term immunosuppressive therapy – Prisoner – Patients on pre-existing continuous reno-renal therapy (CRRT) or intermittent hemodialysis (IHD
Gender Eligibility: All
Minimum Age: 18 Years
Maximum Age: 100 Years
Are Healthy Volunteers Accepted: Accepts Healthy Volunteers
Investigator Details
- Lead Sponsor
- Milton S. Hershey Medical Center
- Provider of Information About this Clinical Study
- Principal Investigator: Anthony Bonavia, Assistant Professor, Department of Anesthesiology – Milton S. Hershey Medical Center
- Overall Official(s)
- Anthony Bonavia, MD, Principal Investigator, Penn State Milton S Hershey Med Ctr
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