Evident, Occult and no Demonstrated USI and UDS Findings in Women With ≥Stage II Cystocele

Overview

Prevalence rates of urodynamic urinary incontinence (USI) subtypes and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation, especially for occult USI. Misdiagnosis of occult USI before cystocele repair might lead to occurrence of de novo stress urinary incontinence after cystocele repair. Thus, the aim of this study was to elucidate the above findings and between-group associations.

Full Title of Study: “Prevalence Rates of Evident, Occult and no Demonstrated Urodynamic Stress Incontinence and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele”

Study Type

  • Study Type: Observational
  • Study Design
    • Time Perspective: Retrospective
  • Study Primary Completion Date: January 31, 2017

Detailed Description

Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. ANOVA test and post-hoc testing with bonferroni's correction were used for statistical analysis. USI is noted during filling cystometry and is defined as the involuntary leakage of urine during increased abdominal pressure, in the absence of a detrusor contraction. The recruited patients with cystocele were classified into three groups (i.e.,evident USI, occult USI and no demonstrated USI) according to pad weight results before and after prolapse reduction.

Interventions

  • Diagnostic Test: Urodynamic study
    • Urodynamic study: including uroflowmetry, filling cystometry, voiding cystometry, and urethral pressure profile

Arms, Groups and Cohorts

  • Evident urodynamic stress incontinence(USI)
    • Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. USI is noted during filling cystometry and is defined as the involuntary leakage of urine during increased abdominal pressure, in the absence of a detrusor contraction.
  • Occult USI
    • Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. USI is noted during filling cystometry and is defined as the involuntary leakage of urine during increased abdominal pressure, in the absence of a detrusor contraction after prolapse reduction by vaginal gauze.
  • ND USI
    • Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent urodynamic studies in a medical center were reviewed. No USI was noted in this group.

Clinical Trial Outcome Measures

Primary Measures

  • Evident USI
    • Time Frame: Between November 2011 and January 2017
    • USI note before reduction of prolapse
  • Occult USI
    • Time Frame: Between November 2011 and January 2017
    • USI note after reduction of prolapse

Participating in This Clinical Trial

Inclusion Criteria

1. Age >20y/o 2. Cystocele > stage II 3. Complete urodynamic study Exclusion Criteria:

1. Pregnancy 2. Urinary tract infection 3. Previous pelvic reconstruction surgery

Gender Eligibility: Female

Minimum Age: 20 Years

Maximum Age: N/A

Are Healthy Volunteers Accepted: No

Investigator Details

  • Lead Sponsor
    • National Taiwan University Hospital
  • Provider of Information About this Clinical Study
    • Sponsor

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